Mapangidwe a Dimethyl

Zamkati

• Musanatenge dimethyl fumarate,
• Dimethyl fumarate ingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, siyani kumwa dimethyl fumarate ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

Dimethyl fumarate imagwiritsidwa ntchito pochiza achikulire omwe ali ndi mitundu yosiyanasiyana ya multiple sclerosis (MS; matenda omwe misempha sagwira ntchito moyenera ndipo anthu amatha kufooka, kufooka, kutayika kwa kulumikizana kwa minofu, komanso mavuto a masomphenya, kulankhula, ndi chikhodzodzo) kuphatikizapo:

• matenda opatsirana (CIS; zizindikiro za mitsempha zomwe zimakhala pafupifupi maola 24),
• mitundu yobwezeretsanso (matenda omwe matenda amawonekera nthawi ndi nthawi), kapena
• mitundu yachiwiri yopita patsogolo (matenda omwe amabwereranso amapezeka pafupipafupi).

Dimethyl fumarate ili m'gulu la mankhwala otchedwa Nrf2 activators. Zimagwira ntchito pochepetsa kutupa komanso kupewa kuwonongeka kwa mitsempha komwe kumatha kuyambitsa matenda a sclerosis.

Dimethyl fumarate imabwera ngati kuchedwa kutulutsidwa (kumatulutsa mankhwala m'matumbo kuti athane ndi kuwonongeka kwa mankhwala ndi zidulo zam'mimba) kapisozi woti amwe pakamwa. Nthawi zambiri amatengedwa kawiri patsiku. Tengani dimethyl fumarate mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani dimethyl fumarate ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dimethyl fumarate ikhoza kutengedwa kapena wopanda chakudya. Komabe, ngati mutenga dimethyl fumarate ndi chakudya kapena ndi aspirin yosakanikirana (325 mg kapena yocheperako) mphindi 30 musanatenge dimethyl fumarate, mumakhala ndi mwayi wochepa woti mudzamvekere mukamalandira chithandizo.

Kumeza makapisozi lonse; musatafune, kapena kuwaphwanya. Osatsegula makapisozi kapena kuwaza zomwe zili mu chakudya.

Dokotala wanu angayambe ndi mlingo wochepa wa dimethyl fumarate ndikuwonjezera mlingo wanu pakatha masiku 7.

Dimethyl fumarate itha kuthandizira kuchepetsa matenda ofoola ziwalo, koma sangawachiritse. Pitirizani kumwa dimethyl fumarate ngakhale mukumva bwino. Osasiya kumwa dimethyl fumarate osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Dimethyl fumarate nthawi zina amagwiritsidwanso ntchito pochiza psoriasis (matenda akhungu momwe mawonekedwe ofiira, amiyala amawumba m'malo ena amthupi). Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge dimethyl fumarate,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi dimethyl fumarate, mankhwala ena aliwonse, kapena chilichonse chopezeka mu makapisozi a dimethyl fumarate. Funsani wamankhwala wanu kapena onani zomwe wodwala akupanga kuti muwone mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati muli ndi matenda amtundu uliwonse, kuphatikiza matenda omwe amabwera ndikudwala matenda osatha, kapena ngati mwakhalapo ndi nkhuku kapena herpes zoster (ming'alu; zotupa zomwe zingachitike mwa anthu omwe ali ndi ndinali ndi nthomba m'mbuyomu); kapena kuchuluka kwama cell oyera.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga dimethyl fumarate, itanani dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Dimethyl fumarate ingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutentha, kufiira, kuyabwa, kapena kutentha kwa khungu
• kutsegula m'mimba
• nseru
• kusanza
• kutentha pa chifuwa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, siyani kumwa dimethyl fumarate ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

• zovuta kumeza kapena kupuma
• kutupa kwa nkhope, mmero, lilime, milomo, maso, manja, mapazi, akakolo, kapena miyendo yakumunsi
• ming'oma
• zidzolo
• kuyabwa
• ukali
• mavuto owonera
• kufooka mbali imodzi ya thupi kapena kusakhazikika kwa mikono kapena miyendo yomwe imakulira pakapita nthawi
• kusintha kwa masomphenya
• kusintha kwa malingaliro anu, kukumbukira, kapena kuzindikira komwe kumabweretsa chisokonezo ndikusintha umunthu
• kutopa kwambiri, kusowa kwa njala, kupweteka kumtunda chakumanja kwa m'mimba mwako, mkodzo wamdima, kapena khungu lachikaso kapena maso
• kufooka mbali imodzi ya thupi kuti worsens pa nthawi; kuphwanya kwa manja kapena miyendo; Kusintha kalingaliridwe kanu, kukumbukira, kuyenda, kulinganiza, kulankhula, maso, kapena nyonga zomwe zimakhala masiku angapo; mutu; kugwidwa; chisokonezo; kapena kusintha kwa umunthu
• kuwotcha, kuyabwa, kuyabwa, kapena kumva khungu mbali imodzi ya thupi kapena nkhope ndi zotupa zopweteka kapena zotupa zomwe zimawonekera masiku angapo pambuyo pake

Dimethyl fumarate ingayambitse mavuto ena. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha komanso kutali ndi kuwala, kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa kuyezetsa magazi musanayambe chithandizo chanu ndipo atha kuyitanitsa mayeso ena a labu panthawi ya chithandizo kuti muwone momwe thupi lanu likuyankhira ku dimethyl fumarate.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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