Mlembi: William Ramirez
Tsiku La Chilengedwe: 21 Sepitembala 2021
Sinthani Tsiku: 13 Novembala 2024
Anonim
Afatinib treatment in squamous cell lung cancer – Video abstract [ID 104177]
Kanema: Afatinib treatment in squamous cell lung cancer – Video abstract [ID 104177]

Zamkati

Afatinib amagwiritsidwa ntchito pochiza mitundu ina ya khansa ya m'mapapo yaing'ono yomwe yafalikira kumatenda oyandikira kapena mbali zina za thupi. Afatinib ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa kuchitapo kanthu mwachilengedwe komwe kumafunikira kuti maselo a khansa achulukane.

Afatinib imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa m'mimba yopanda kanthu kamodzi patsiku, osachepera ola limodzi isanakwane kapena maola awiri mutadya chakudya kapena chotupitsa. Tengani afatinib mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani afatinib ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu akhoza kuyimitsa chithandizo chanu kwakanthawi kapena kosatha kapena kuchepa kwa mulingo ngati mukukumana ndi zovuta za afatinib. Lankhulani ndi dokotala wanu za momwe mukumvera mukamalandira chithandizo.


Pitirizani kutenga afatinib ngakhale mutakhala bwino. Osasiya kumwa afatinib osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanatenge afatinib,

  • uzani dokotala wanu komanso wamankhwala kuti ngati muli ndi vuto la afatinib, mankhwala ena aliwonse, kapena chilichonse mwazipangizo za afatinib. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: amiodarone (Cordarone, Pacerone); mankhwala ena oletsa mafungal monga itraconazole (Sporanox) ndi ketoconazole (Nizoral); cyclosporine (Gengraf, Neoral, Sandimmune); erythromycin (EES, Erythrocin, ena); mankhwala ena amtundu wa kachilombo ka HIV monga nelfinavir (Viracept), ritonavir (Norvir, ku Kaletra), ndi saquinavir (Invirase); mankhwala ena ogwidwa monga carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, ndi phenytoin (Dilantin); quinidine (mu Nuedexta); rifampin (Rimactane, Rifadin, mu Rifater); tacrolimus (Prograf); ndi verapamil (Calan, Covera, Isoptin, Verelan). Mankhwala ena ambiri amathanso kulumikizana ndi afatinib, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
  • auzeni adotolo ngati muli ochokera ku Asia kapena mudakhalapo ndi vuto lamapapu kapena kupuma (kupatula khansa yamapapu); mavuto amaso, kuphatikiza maso owuma; mavuto amtima; chiwindi kapena matenda a impso; kapena matenda aliwonse. Komanso, uzani dokotala ngati muvala magalasi olumikizirana.
  • Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Simuyenera kutenga pakati mukamamwa afatinib komanso kwa milungu iwiri musanalandire chithandizo. Lankhulani ndi dokotala wanu za njira zolerera zomwe mungagwiritse ntchito mukamachiza. Mukakhala ndi pakati mukatenga afatinib, itanani dokotala wanu mwachangu. Afatinib itha kuvulaza mwana wosabadwayo.
  • uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwitsa mukamamwa afatinib.
  • konzekerani kupeŵa kuwunika kwa dzuwa kosafunikira kapena kwanthawi yayitali komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zoteteza ku dzuwa. Afatinib imatha kupangitsa khungu lanu kuzindikira kuwala kwa dzuwa. Kuwonetseredwa ndi kuwala kwa dzuwa kumawonjezera chiopsezo kuti mutha kukhala ndi zotupa kapena ziphuphu pamankhwala anu ndi afatinib.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati pasanathe maola 12 musanakonzekere kumwa mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Afatinib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kung'amba kapena kutupa kwa milomo kapena zilonda m'makona am'kamwa
  • khungu louma kapena kuyabwa
  • kusowa chilakolako
  • matenda a msomali
  • ziphuphu
  • mphuno kutuluka magazi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, siyani kumwa afatinib ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

  • kutsegula m'mimba
  • pakamwa pouma, mkodzo wakuda, kuchepa thukuta, khungu louma, ndi zizindikiro zina zakumwa madzi m'thupi
  • kuchepa pokodza
  • kutupa kwa mikono, manja, mapazi, akakolo, kapena miyendo yakumunsi
  • zidzolo
  • ululu, kufiira, khungu, kapena kuphulika kwa khungu
  • kuvuta kupuma
  • kupuma movutikira
  • kugunda kwamtima msanga, kosasinthasintha, kapena kwamphamvu
  • kunenepa mwadzidzidzi
  • chifuwa
  • malungo
  • kutopa kwambiri
  • kupweteka kumtunda chakumanja kwam'mimba
  • kuvulaza kapena kutuluka mwachilendo
  • nseru
  • kusanza
  • chikasu cha khungu kapena maso
  • mkodzo wakuda
  • ofiira, otupa, opweteka, kapena misozi
  • kusintha kwamwadzidzidzi m'masomphenya, kuphatikiza kusawona bwino
  • kutengeka ndi kuwala

Afatinib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.


Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha komanso kutali ndi kuwala, kutentha kwambiri, ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

  • nseru
  • kusanza
  • kufooka
  • chizungulire
  • mutu
  • kupweteka m'mimba

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone kuyankha kwa thupi lanu ku afatinib.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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