Idelalisib

Zamkati

• Musanadye idelalisib,
• Idelalisib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

Idelalisib ikhoza kuwononga chiwindi chachikulu kapena choopsa. Uzani dokotala wanu ngati mwakhalapo ndi matenda a chiwindi. Chiwopsezo cha kuwonongeka kwa chiwindi chitha kuwonjezeka mwa anthu omwe amamwa mankhwala ena omwe amadziwika kuti amawononga chiwindi, komanso mwa anthu omwe ali ndi matenda a chiwindi. Uzani dokotala wanu komanso wamankhwala zamankhwala omwe mukumwa kuti athe kuwona ngati mankhwala anu angawonjezere chiwopsezo kuti chiwindi chitha kuwonongeka mukamalandira chithandizo cha idelalisib. Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo: kutopa kwambiri, kusowa kwa njala, kuchepa thupi, nseru, kusanza, kutuluka mwazi kosazolowereka kapena kufinya, khungu lachikaso kapena maso, mkodzo wakuda wachikaso kapena bulauni, mipando yotumbululuka , kapena kupweteka kumtunda chakumanja kwam'mimba.

Idelalisib ikhoza kuyambitsa kutsekula m'mimba, colitis (kutupa kwa m'matumbo akulu), kapena mabowo m'mimba kapena m'matumbo. Uzani dokotala wanu ngati muli ndi matenda otsekula m'mimba kapena ngati mudakhalapo ndi matenda am'mimba kapena zina zomwe zimakhudza m'mimba kapena m'matumbo. Chiwopsezo chotsekula m'mimba chingawonjezeke mwa anthu omwe amamwa mankhwala ena omwe amadziwika kuti amayambitsa kutsekula m'mimba. Uzani dokotala wanu komanso wamankhwala zamankhwala omwe mukumwa kuti athe kuwona ngati mankhwala anu angawonjezere chiwopsezo chotenga matenda m'mimba mukamalandira mankhwala ndi idelalisib. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: ngati kuchuluka kwa matumbo anu patsiku kumawonjezeka ndi 6 kapena kupitilira apo, kukokana m'mimba kapena kupweteka, kuzizira, malungo, nseru, kapena kusanza.

Idelalisib ingayambitse pneumonitis yowopsa kapena yoopsa (kutupa kwa mapapo). Uzani dokotala wanu ngati muli ndi matenda am'mapapo kapena kupuma. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: chifuwa chatsopano kapena chowonjezeka, kupuma movutikira, kupumira, kapena kupuma pang'ono.

Idelalisib ikhoza kuyambitsa matenda oopsa kapena owopsa. Uzani dokotala wanu ngati muli ndi matenda, kapena ngati mwakhalapo ndi cytomegalovirus (CMV; matenda opatsirana omwe angayambitse zizindikiro kwa odwala omwe ali ndi chitetezo chamthupi chofooka). Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo: malungo, zilonda zapakhosi, kuzizira, kupweteka, pafupipafupi, kapena kukodza kovuta, kapena zizindikilo zina za matenda.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena kuti muwone momwe thupi lanu likuyankhira idelalisib.

Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito idelalisib.

Idelalisib imagwiritsidwa ntchito limodzi ndi mankhwala ena a rituximab (Rituxan) kuti athetse matenda a khansa ya m'magazi (CLL; mtundu wa khansa womwe umayambira m'maselo oyera am'magazi) mwa anthu omwe khansa idabweranso atalandira chithandizo china cha khansa. Amagwiritsidwanso ntchito kuthana ndi mitundu ina ya follicular lymphoma (FL; mtundu wa khansa womwe umayambira m'maselo oyera amwazi) ndi ma lymphocytic lymphoma (SLL: mtundu wa khansa womwe umayambira m'maselo oyera amwazi) mwa anthu omwe khansa yawo idabwera kubwerera atalandira chithandizo chamankhwala osachepera awiri a khansa. Idelalisib ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa mapuloteni achilendo omwe amawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuletsa kufalikira kwa maselo a khansa.

Idelalisib amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa kapena wopanda chakudya kawiri patsiku. Tengani idelalisib mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani idelalisib ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Dokotala wanu akhoza kuchepetsa mlingo wanu wa idelalisib kapena kukuuzani kuti musiye kumwa mankhwalawo kwakanthawi kapena kwanthawi zonse ngati mungakhale ndi zovuta zina mukamalandira chithandizo. Izi zimadalira momwe mankhwalawa amakuthandizirani komanso zovuta zomwe mumakumana nazo. Lankhulani ndi dokotala wanu za momwe mukumvera mukamalandira chithandizo. Pitilizani kumwa idelalisib ngakhale mukumva bwino. Osasiya kumwa idelalisib osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanadye idelalisib,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi idelalisib, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a idelalisib. Ngati munakhalapo ndi vuto linalake m'mbuyomu, monga kutupa kwa nkhope yanu, milomo kapena mmero; zovuta kumeza kapena kupuma; kapena khungu losalala, khungu lanu lingakuwuzeni kuti musatenge idelalisib.Funsani wamankhwala kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazopangira.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: carbamazepine (Carbatrol, Epitol, Equetro, ena); clarithromycin (Biaxin, mu PrevPac); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); Mankhwala omwe amachiza kachilombo ka HIV monga efavirenz (Sustiva, ku Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, ku Kaletra, ku Technivie); masewera; nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos, mu Actoplus Met, ku Duetact, ku Oseni); rifabutin (Mycobutin); ndi rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi idelalisib, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu komanso wazamankhwala zomwe mumamwa mankhwala azitsamba, makamaka wort ya St. Simuyenera kutenga wort ya St. John mukamamwa mankhwala ndi idelalisib.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena konzekerani kukhala ndi mwana. Simuyenera kutenga pakati mukamamwa ndi idelalisib.Muyenera kugwiritsa ntchito njira zakulera kuti muchepetse mimba mukamalandira chithandizo cha idelalisib komanso osachepera mwezi umodzi mutatha kumwa. Ngati ndinu wamwamuna ndipo mnzanu atha kukhala ndi pakati, muyenera kugwiritsa ntchito njira yolerera yoyenerera mukamalandira chithandizo komanso kwa miyezi itatu mutalandira mankhwala. Ngati inu kapena mnzanu mutakhala ndi pakati mukatenga idelalisib, itanani dokotala wanu mwachangu. Idelalisib atha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa idelalisib komanso kwa mwezi umodzi mutatha kumwa.

Lankhulani ndi dokotala wanu za kudya mphesa ndi kumwa madzi amphesa mukamamwa mankhwalawa.

Ngati mwaphonya mlingo wa idelalisib pasanathe maola 6, tengani mlingo womwe mwaphonya mukangokumbukira kenako mutenge mlingo wotsatira panthawiyo. Komabe, ngati mwaphonya mlingo wa maola opitilira 6, tulukani mulingo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Idelalisib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mutu
• kuvuta kugona kapena kugona
• kuchepa kudya
• ludzu lowonjezeka
• kutentha pa chifuwa
• kupweteka pamodzi
• thukuta usiku
• kusowa mphamvu
• kutupa kwa manja, mapazi, akakolo, kapena miyendo yakumunsi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• khungu lofiira, kuyabwa, khungu, kapena khungu
• zilonda zopweteka kapena zilonda pakhungu lanu, milomo, kapena mkamwa mwanu
• zovuta kumeza kapena kupuma; kutupa kwa nkhope, milomo, kapena mmero; ming'oma; kuyabwa

Idelalisib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha komanso kutali ndi kuwala, kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zydelig^®