Mlembi: Clyde Lopez
Tsiku La Chilengedwe: 22 Kulayi 2021
Sinthani Tsiku: 18 Novembala 2024
Anonim
Cariprazine Aims to Further Antipsychotic Market for Mental Health
Kanema: Cariprazine Aims to Further Antipsychotic Market for Mental Health

Zamkati

Chenjezo lofunika kwa okalamba omwe ali ndi matenda amisala:

Kafukufuku wasonyeza kuti achikulire omwe ali ndi dementia (vuto laubongo lomwe limakhudza kukumbukira, kuganiza bwino, kulumikizana, ndikuchita zochitika zatsiku ndi tsiku zomwe zitha kusintha kusintha kwa malingaliro ndi umunthu) omwe amatenga ma antipsychotic (mankhwala amisala) monga cariprazine khalani ndi mwayi wambiri wakufa panthawi yachithandizo. Achikulire achikulire omwe ali ndi matenda a dementia amathanso kukhala ndi mwayi wambiri wopwetekedwa mtima kapena kupwetekedwa pang'ono panthawi yachipatala.

Cariprazine sivomerezedwa ndi Food and Drug Administration (FDA) pochiza zovuta zamakhalidwe kwa achikulire omwe ali ndi vuto la misala. Lankhulani ndi dokotala yemwe adakupatsani mankhwalawa ngati inu, wachibale wanu, kapena wina aliyense amene mumamusamalira ali ndi matenda amisala ndipo akuchiritsidwa ndi cariprazine. Kuti mumve zambiri pitani patsamba la FDA: http://www.fda.gov/Drugs.

Chenjezo lofunikira kwa anthu omwe ali ndi zovuta zakumapeto:

Chiwerengero chochepa cha ana, achinyamata, komanso achikulire (mpaka zaka 24) omwe amamwa mankhwala opatsirana pogonana ('ma elevator') monga cariprazine panthawi yamaphunziro azachipatala adayamba kudzipha (kuganiza zodzivulaza kapena kudzipha kapena kukonzekera kapena kuyesa kutero ). Ana, achinyamata, komanso achikulire omwe amamwa mankhwala opanikizika kuti athetse kuvutika maganizo kapena matenda ena amisala atha kukhala ofuna kudzipha kuposa ana, achinyamata, komanso achikulire omwe samamwa mankhwala opatsirana kuti athetse vutoli. Komabe, palinso zoopsa ngati vuto la kukhumudwa silichiritsidwa kwa ana ndi achinyamata. Lankhulani ndi dokotala wa mwana wanu za zoopsazi komanso ngati mwana wanu ayenera kumwa mankhwala opatsirana. Cariprazine sanaphunzirepopo kwa ana ochepera zaka 18.


Muyenera kudziwa kuti thanzi lanu lamisala lingasinthe m'njira zosayembekezereka mukamamwa cariprazine kapena mankhwala ena opatsirana ngakhale mutakhala wamkulu kuposa zaka 24. Mutha kudzipha, makamaka kumayambiriro kwa chithandizo chanu komanso nthawi iliyonse yomwe mlingo wanu ukuwonjezeka kapena kutsika. Inu, banja lanu, kapena amene amakusamalirani muyenera kuyimbira dokotala nthawi yomweyo mukakumana ndi izi: kukhumudwa kwatsopano kapena kukulira; kuganiza zodzipweteka kapena kudzipha, kapena kukonzekera kapena kuyesa kutero; kuda nkhawa kwambiri; kusakhazikika; mantha; zovuta kugona kapena kugona; nkhanza; kukwiya; kuchita mosaganizira; kusakhazikika kwakukulu; ndi chisangalalo chachilendo. Onetsetsani kuti banja lanu kapena amene akukusamalirani akudziwa zomwe zingakhale zovuta kuti athe kuyimbira dokotala ngati mukulephera kupeza chithandizo chanokha.

Wothandizira zaumoyo wanu adzafuna kukuwonani nthawi zambiri mukamamwa cariprazine, makamaka kumayambiriro kwa chithandizo chanu. Onetsetsani kuti mwasunga nthawi yonse yoyendera ofesi yanu ndi dokotala.


Dokotala kapena wamankhwala amakupatsirani pepala lazidziwitso zaopanga (Medication Guide) mukayamba mankhwala ndi cariprazine. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kupeza Buku la Mankhwala kuchokera patsamba la FDA: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.

Ziribe kanthu msinkhu wanu, musanamwe mankhwala opondereza, inu kapena amene amakusamalirani muyenera kukambirana ndi dokotala za kuopsa ndi zabwino zakuchiza matenda anu ndi mankhwala opondereza kapena mankhwala ena. Muyeneranso kukambirana za kuopsa ndi maubwino osachiza matenda anu. Muyenera kudziwa kuti kukhumudwa kapena matenda amisala kumawonjezera chiopsezo chodzipha. Vutoli limakhala lalikulu ngati inu kapena aliyense m'banja mwanu mwakhalapo kapena mwakhalapo ndi vuto losinthasintha zochitika (kusinthasintha komwe kumachokera pakukhumudwa ndikukhala osangalala kwambiri) kapena mania (kukwiya, kusangalala modabwitsa) kapena kuganizira kapena kuyesa kudzipha. Lankhulani ndi dokotala wanu za matenda anu, zizindikiro zanu, komanso mbiri yazachipatala yanokha komanso yabanja. Inu ndi dokotala wanu mudzasankha mtundu wa chithandizo choyenera kwa inu.


Lankhulani ndi dokotala wanu za kuopsa kotenga cariprazine.

Cariprazine amagwiritsidwa ntchito pochiza schizophrenia (matenda amisala omwe amachititsa kusokonezeka kapena kuganiza kwachilendo, kutaya chidwi m'moyo, komanso kukhudzidwa mwamphamvu kapena kosayenera). Cariprazine imagwiritsidwanso ntchito kuthana ndi matenda okhumudwa mwa anthu omwe ali ndi bipolar I disorder (manic depression disorder; matenda omwe amayambitsa magawo amanjenje, magawo andewu ndi zina zosakhala bwino). Amagwiritsidwanso ntchito ngati chithandizo chanthawi yayitali yamagawo amisala kapena magawo osakanikirana (zizindikilo za mania ndi kukhumudwa zomwe zimachitika limodzi) mwa anthu omwe ali ndi vuto la kusinthasintha zochitika. Cariprazine ali mgulu la mankhwala otchedwa atypical antipsychotic. Zimagwira ntchito posintha zochitika za zinthu zina zachilengedwe muubongo.

Cariprazine amabwera ngati kapisozi woti amwe pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku kapena wopanda chakudya. Tengani cariprazine mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani cariprazine ndendende monga momwe akuuzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu mwina angakuyambitseni ndi cariprazine yochepa ndipo pang'onopang'ono muwonjezere mlingo wanu kutengera momwe mankhwalawo amakuthandizirani, komanso zovuta zomwe mumakumana nazo.

Cariprazine itha kuthandizira kuwongolera zizindikilo zanu koma sichitha matenda anu. Zitha kutenga milungu ingapo kapena kupitilira apo kuti mumve bwino cariprazine. Pitirizani kumwa cariprazine ngakhale mukumva bwino. Osasiya kumwa cariprazine osalankhula ndi dokotala. Lankhulani ndi dokotala wanu ngati simukumva kuti mukuchira panthawi yomwe mukuchiritsidwa ndi cariprazine.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanamwe cariprazine,

  • uzani dokotala wanu komanso wamankhwala kuti ngati muli ndi vuto la cariprazine, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi a cariprazine. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: anticholinergics monga atropine (Atropen, Duodote, Enlon-Plus), benztropine (Cogentin), dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine, propantheline (Pro-Banthine), ndi scopolamine ( Zowonjezera za Transderm); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); itraconazole (Onmel, Sporanox); ketoconazole; mankhwala a kuthamanga kwa magazi; ndi rifampin (Rifadin, Rimactane, ku Rifamate, Rifater). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi cariprazine, chifukwa chake onetsetsani kuti mumauza dokotala za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
  • uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
  • uzani dokotala wanu ngati muli ndi maselo oyera oyera ochepa, kapena ngati mwapezapo maselo oyera oyera ochepa ngati mankhwala omwe mudamwa. Uzani dokotala wanu ngati mwakhalapo kapena munagwapo; sitiroko; utumiki; matenda a mtima; mtima kulephera; kugunda kwamtima; kuvuta kusunga malire; Kuvuta kumeza; kapena matenda a mtima, chiwindi, kapena impso. Muuzeni dokotala wanu ngati mukusanza kwambiri, kutsekula m'mimba kapena zizindikiro zakusowa madzi m'thupi tsopano, kapena ngati mukukhala ndi zizindikiritsozi nthawi iliyonse mukamalandira chithandizo.
  • uzani dokotala wanu ngati muli ndi pakati, makamaka ngati muli m'miyezi ingapo yapitayo ya mimba yanu, kapena ngati mukufuna kutenga pakati kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga cariprazine, itanani dokotala wanu. Cariprazine imatha kubweretsa mavuto kwa ana obadwa kumene atabereka ngati atamwa m'miyezi yapitayi yamimba.
  • muyenera kudziwa kuti cariprazine imatha kukupangitsani kugona, ndipo ingakhudze luso lanu loganiza bwino, kupanga zisankho, komanso kuchitapo kanthu mwachangu. Musayendetse galimoto kapena kugwiritsa ntchito makina panthawi yamankhwala anu ndi cariprazine mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
  • muyenera kudziwa kuti mutha kukhala ndi hyperglycemia (kuchuluka kwa shuga m'magazi anu) mukalandira mankhwalawa, ngakhale mulibe matenda ashuga. Ngati muli ndi schizophrenia, mumakhala ndi matenda ashuga kuposa anthu omwe alibe schizophrenia ndikulandila cariprazine kapena mankhwala omwewo akhoza kuwonjezera ngozi imeneyi. Uzani dokotala wanu nthawi yomweyo ngati muli ndi zizindikiro zotsatirazi mukamalandira chithandizo: ludzu lokwanira, kukodza pafupipafupi, njala yayikulu, kusawona bwino, kapena kufooka. Ndikofunika kuyimbira dokotala wanu mukangokhala ndi izi, chifukwa shuga wambiri m'magazi amatha kuyambitsa vuto lalikulu lotchedwa ketoacidosis. Ketoacidosis imatha kukhala pangozi ngati singachiritsidwe koyambirira. Zizindikiro za ketoacidosis zimaphatikizapo: pakamwa pouma, nseru ndi kusanza, kupuma movutikira, mpweya womwe umanunkhira zipatso, ndikuchepetsa chidziwitso.
  • muyenera kudziwa kuti cariprazine imatha kuyambitsa chizungulire, mutu wopepuka, komanso kukomoka mukadzuka mwachangu pamalo abodza. Izi ndizofala kwambiri mukayamba kumwa cariprazine. Pofuna kupewa vutoli, tulukani pabedi pang'onopang'ono, ndikupumitsa mapazi anu pansi kwa mphindi zingapo musanayimirire.
  • muyenera kudziwa kuti cariprazine itha kupangitsa kuti thupi lanu lizizizira kuzizira mukatentha kwambiri. Uzani dokotala wanu ngati mukufuna kuchita masewera olimbitsa thupi mwamphamvu kapena kutentha kwambiri.Onetsetsani kuti mumamwa madzi ambiri ndikuyimbira dokotala ngati mukukumana ndi izi: Kumva kutentha kwambiri, kutuluka thukuta kwambiri, osatuluka thukuta ngakhale kuli kotentha, mkamwa mouma, ludzu kwambiri, kapena kuchepa pokodza.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Cariprazine angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kutopa kwambiri
  • kusakhazikika
  • nkhawa
  • kubvutika
  • kuvuta kugona kapena kugona
  • chizungulire, kumva kusakhazikika, kapena kukhala ndi vuto loti musamachite zinthu mopitirira malire
  • kuchuluka kudya
  • kunenepa
  • kudzimbidwa
  • kudzimbidwa
  • nseru
  • kuchuluka malovu kapena malovu
  • kusawona bwino

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mgulu la CHENJEZO CHENJEZO kapena ZOCHITIKA ZAPADERA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

  • kugwidwa
  • kusuntha kwachilendo kwa thupi lanu kapena nkhope yomwe simungathe kuyendetsa
  • kuyenda pang'onopang'ono kapena kuyenda pang'ono
  • kutaya kusuntha
  • kugwa
  • malungo, thukuta, chisokonezo, kupuma mofulumira, kugunda kwamtima kapena kosasinthasintha, komanso kuuma kwambiri kwa minofu
  • kufooka kwa minofu kapena kupweteka
  • mawonekedwe opanda nkhope
  • zovuta kumeza kapena kupuma
  • zolimba pakhosi
  • lilime lomwe limatuluka pakamwa
  • zidzolo
  • kuyabwa
  • ming'oma
  • kutupa kwa nkhope, mmero, lilime, milomo, kapena maso
  • mkodzo wakuda kapena kola
  • kutupa miyendo ndi mapazi
  • kuchepa pokodza

Cariprazine imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

  • kukhalitsa
  • kumverera opanda mutu, chizungulire kapena kukomoka mukaimirira pomwe mwakhala kapena kugona pansi

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone momwe thupi lanu limayankhira pa cariprazine.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Kutulutsa®
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