Eluxadoline

Zamkati

• Musanatenge eluxadoline,
• Eluxadoline imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi chimodzi mwazizindikirozi, siyani kumwa eluxadoline ndikuyimbira dokotala nthawi yomweyo kapena kupeza chithandizo chamankhwala mwadzidzidzi:

Eluxadoline imagwiritsidwa ntchito pochiza matenda am'mimba opatsirana ndi kutsekula m'mimba (IBS-D; zomwe zimayambitsa kupweteka m'mimba, kuponderezana, kapena zotchinga kapena zotchinga) mwa akulu. Eluxadoline ali mgulu la mankhwala otchedwa mu-opioid receptor agonists.Zimagwira ntchito pochepetsa kuchepa kwa matumbo.

Eluxadoline imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa ndi chakudya kawiri patsiku. Tengani eluxadoline mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani eluxadoline ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Eluxadoline ikhoza kukhala chizolowezi. Musatenge mlingo wokulirapo, tengani nthawi zambiri, kapena tengani nthawi yayitali kuposa momwe adalangizire dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge eluxadoline,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi eluxadoline, mankhwala ena aliwonse, kapena chilichonse mwapiritsi a eluxadoline. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: alfentanil (Alfenta); alosetron (Lotronex); maantibayotiki monga ciprofloxacin (Cipro) ndi clarithromycin (Biaxin, ku Prevpac); mankhwala a anticholinergic monga benztropine (Cogentin), dicyclomine (Bentyl), diphenhydramine (Benadryl); bupropion (Forfivo XL, Wellbutrin, Zyban, ena); eltrombopag (Promacta); mankhwala amtundu wa ergot monga dihydroergotamine (DHE 45, Migranal) ndi ergotamine tartrate (Ergomar, ku Cafergot, ku Migergot); fentanyl (Abstral, Actiq, Duragesic, Sublimaze, ena); fluconazole (Diflucan); gemfibrozil (Lopid); mankhwala a HIV monga atazanavir (Reyataz, ku Evotaz), lopinavir (Kaletra), ritonavir (Norvir, ku Kaletra, ku Viekira Pak), saquinavir (Invirase), ndi tipranavir (Aptivus); mankhwala omwe amaletsa chitetezo cha mthupi monga cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), ndi tacrolimus (Astagraf, Envarsus XR, Prograf); opiate (mankhwala osokoneza bongo) mankhwala opweteka; paroxetine (Brisdelle, Paxil, Pexeva); pimozide (Orap); quinidine (mu Nuedexta); rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); ndi rosuvastatin (Crestor). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• muyenera kudziwa kuti mutha kumwa loperamide (Imodium AD) nthawi zina kuti muchiritse kutsegula m'mimba kwambiri mukamamwa eluxadoline. Lekani kumwa loperamide nthawi yomweyo mukadzimbidwa.
• uzani dokotala wanu ngati mukudwala tsopano kapena ngati nthawi zambiri mumadzimbidwa, ngati mumamwa kapena mumamwa mowa wambiri (zoposa 3 zakumwa zoledzeretsa patsiku), kapena ngati mulibe ndulu. Uzaninso dokotala wanu ngati mwakhalapo ndi zotchinga za bile (kutsekeka m'machubu zomwe zimanyamula bile kuchokera pachiwindi kupita ku ndulu ndi m'matumbo ang'ono), sphincter wa Oddi kukanika (kutsekeka kwa ndulu kapena timadziti ta m'mimba tomwe timayenderera m'matumbo omwe amayambitsa kupweteka kapena jaundice), kutsekeka m'matumbo mwanu, kapamba (kutupa kwa kapamba komwe sikupita), kapena matenda a chiwindi. Dokotala wanu angakuuzeni kuti musatenge eluxadoline.
• uzani dokotala wanu ngati mwakhalapo ndi matenda a impso.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga eluxadoline, itanani dokotala wanu.
• Muyenera kudziwa kuti eluxadoline imatha kukupangitsani kugona, makamaka ngati muli ndi matenda a chiwindi. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
• uzani dokotala ngati mumamwa mowa nthawi zonse kapena nthawi zina mumamwa mowa wambiri nthawi yochepa. Funsani dokotala wanu za zakumwa zoledzeretsa pamene mukumwa eluxadoline. Kumwa mowa kungapangitse kuti mukhale ndi vuto lodana ndi kapamba.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo wosowa mukangokumbukira ndi chakudya. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Eluxadoline imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi chimodzi mwazizindikirozi, siyani kumwa eluxadoline ndikuyimbira dokotala nthawi yomweyo kapena kupeza chithandizo chamankhwala mwadzidzidzi:

• ululu womwe umayambira kumtunda koma utha kufalikira kumbuyo kapena phewa ndi nseru komanso kusanza
• kudzimbidwa kwakukulu
• zidzolo; ming'oma; kutupa nkhope kapena pakhosi; kupuma movutikira; kukhazikika pakhosi; kupweteka pachifuwa kapena kulimba; kapena kuvutika kumeza kapena kupuma

Eluxadoline ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu.

Musalole kuti aliyense azimwa mankhwala anu. Eluxadoline ndichinthu cholamulidwa. Malangizo amatha kudzazidwanso kangapo; funsani wamankhwala wanu ngati muli ndi mafunso.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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