Talimogene Laherparepvec jekeseni

Zamkati

• Asanalandire jakisoni wa talimogene laherparepvec,
• Talimogene laherparepvec jakisoni amatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mu gawo la MAWONEKEDWE OTHANDIZA, pitani kuchipatala nthawi yomweyo:

Talimogene laherparepvec jakisoni amagwiritsidwa ntchito pochiza khansa ina ya khansa yapakhungu yotchedwa melanoma (mtundu wa khansa yapakhungu) zotupa zomwe sizingachotsedwe maopareshoni kapena zomwe zimabweranso atachitidwa opaleshoni. Talimogene laherparepvec ali mgulu la mankhwala otchedwa ma oncolytic virus. Ndi mtundu wofooka komanso wosintha wa Herpes Simplex Virus Type I (HSV-1 'virus yozizira) yomwe imagwira ntchito pothandiza kupha ma cell a khansa.

Talimogene laherparepvec jakisoni amabwera ngati kuyimitsa (madzi) kuti alandire jakisoni ndi dokotala kapena namwino kuofesi yazachipatala. Dokotala wanu amalowetsa mankhwalawo mwachindunji m'matenda omwe ali pakhungu lanu, pansi pa khungu lanu, kapena m'matumbo anu. Mudzalandira chithandizo chachiwiri pakatha masabata atatu mutalandira chithandizo choyamba, kenako milungu iwiri iliyonse pambuyo pake. Kutalika kwa chithandizo kumadalira momwe zotupa zanu zimayankhira kuchipatala. Dokotala wanu sangabayire zotupa zonse paulendo uliwonse.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi talimogene laherparepvec ndipo nthawi iliyonse yomwe mumalandira jakisoni. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jakisoni wa talimogene laherparepvec,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi talimogene laherparepvec, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu jakisoni wa talimogene laherparepvec. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• uzani dokotala ngati mukumwa mankhwala aliwonse omwe amachepetsa chitetezo chamthupi chanu monga antithymocyte globulin (Atgam, Thymoglobulin), azathioprine (Azasan, Imuran), basiliximab (Simulect), belatacept (Nulojix), belimumab (Benlysta), cortisone, cyclosporine ( Gengraf, Neoral, Sandimmune), dexamethasone, fludrocortisone, methotrexate (Otrexup, Rasuvo, Trexall), methylprednisolone (Depo-medrol, Medrol, Solu-medrol), mycophenolate mofetil (Cellcept), prednisolone (Flopred, Orapred, Pediapred, Pediapred. Rayos), sirolimus (Rapamune), ndi tacrolimus (Astagraf XL, Prograf, Envarsus XR). Mankhwala ena ambiri amathanso kufooketsa chitetezo cha mthupi lanu, onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angakuuzeni kuti musalandire talimogene laherparepvec ngati mukumwa mankhwala amodzi kapena angapo.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: mankhwala aliwonse achilengedwe monga acyclovir (Sitavig, Zovirax), cidofovir, docosanol (Abreva), famciclovir (Famvir), foscarnet (Foscavir), ganciclovir (Cytovene), penciclovir (Denavir), trifluridine Viroptic), valacyclovir (Valtrex), ndi valganciclovir (Valcyte). Mankhwalawa angakhudze momwe talimogene laherparepvec imagwirira ntchito kwa inu.
• auzeni adotolo ngati mwakhalapo ndi khansa ya m'magazi (khansa yamagazi oyera), lymphoma (khansa ya gawo limodzi lama chitetezo cha mthupi), kachilombo ka HIV (kachilombo ka HIV), muli ndi matenda a immunodeficiency (AIDS), kapena matenda ena aliwonse zomwe zimayambitsa chitetezo chamthupi chofooka. Dokotala wanu mwina sakufuna kuti musalandire jakisoni wa talimogene laherparepvec.
• Uzani dokotala wanu ngati mwakhalapo ndi mankhwala a radiation m'dera la zotupa za khansa ya pakhungu, myeloma yambiri (khansa ya maselo am'magazi am'mafupa), mtundu uliwonse wamatenda amthupi (momwe chitetezo cha mthupi chimagwirira mbali zabwino za thupi ndikupangitsa kupweteka, kutupa, ndi kuwonongeka), kapena ngati mumalumikizana kwambiri ndi munthu yemwe ali ndi pakati kapena amene ali ndi chitetezo chamthupi chofooka.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Simuyenera kutenga pakati mukamamwa mankhwala a talimogene laherparepvec. Lankhulani ndi dokotala wanu za njira zolerera zomwe mungagwiritse ntchito mukamachiza. Mukakhala ndi pakati mukalandira jakisoni wa talimogene laherparepvec, pitani kuchipatala nthawi yomweyo. Talimogene laherparepvec jakisoni akhoza kuvulaza mwana wosabadwayo.
• Muyenera kudziwa kuti jakisoni wa talimogene laherparepvec uli ndi kachilombo kamene kangafalikire ndikupatsira anthu ena. Muyenera kusamala kuti muziphimba malo onse opangira jakisoni ndi mabandeji otchinga komanso opanda madzi kwa sabata limodzi mutalandira chithandizo chilichonse, kapena kupitilira apo ngati jekeseni ikuwomba. Mabandeji akatuluka kapena kugwa, onetsetsani kuti mukuwasintha nthawi yomweyo. Muyenera kugwiritsa ntchito golovu kapena magolovesi a latex mukamamanga bandira malo obayira. Muyenera kuwonetsetsa kuti mwaika zonse zotsukira, magolovesi, ndi mabandeji omwe amagwiritsidwa ntchito popangira jekeseni mu thumba la pulasitiki losindikizidwa ndikuzitaya kudzala.
• simuyenera kukhudza kapena kukanda malo opangira jekeseni kapena mabandeji. Izi zitha kufalitsa kachilomboka mumankhwala a talimogene laherparepvec mbali zina za thupi lanu. Anthu omwe akuzungulirani ayenera kusamala kuti asakhudzane ndi malo obayira, ma bandeji, kapena madzi amthupi. Itanani dokotala wanu nthawi yomweyo ngati inu, kapena aliyense wokuzungulirani, akupanga zizindikiro za matenda a herpes;: kupweteka, kuwotcha, kapena kumenyera chotupa pakamwa panu, kumaliseche, zala, kapena makutu; kupweteka kwa diso, kufiira, kapena kung'amba; kusawona bwino; kutengeka ndi kuwala; kufooka m'manja kapena miyendo; kugona kwambiri; kapena kusokonezeka m'maganizo.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Talimogene laherparepvec jakisoni amatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutopa kwachilendo
• nseru
• kusanza
• kutsegula m'mimba
• kudzimbidwa
• kupweteka m'mimba
• mutu
• chizungulire
• kuonda
• khungu lowuma, losweka, loyabwa, lotentha
• kupweteka kwa minofu kapena molumikizana
• kupweteka kwa mikono kapena miyendo
• Kuchepetsa machiritso a malo obayira
• kupweteka kumalo opangira jekeseni

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mu gawo la MAWONEKEDWE OTHANDIZA, pitani kuchipatala nthawi yomweyo:

• kupuma movutikira kapena mavuto ena opuma
• chifuwa
• pinki, kola wachikuda, kapena mkodzo wa thovu
• kutupa kwa nkhope, manja, mapazi, kapena mmimba
• kutaya mtundu pakhungu lako, tsitsi, kapena maso
• ofunda, ofiira, otupa, kapena khungu lopweteka mozungulira jekeseni
• malungo, zilonda zapakhosi, kuzizira, kapena zizindikiro zina za matenda
• minofu yakufa kapena zilonda zotseguka pamatenda obayidwa

Talimogene laherparepvec jakisoni amatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu.

Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudza jekeseni wa talimogene laherparepvec.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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