Jekeseni wa Dupilumab

Zamkati

• Musanagwiritse ntchito jakisoni wa dupilumab,
• Jekeseni wa Dupilumab itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
• Ngati mukumane ndi izi, siyani kugwiritsa ntchito jakisoni wa dupilumab ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

Jekeseni wa Dupilumab amagwiritsidwa ntchito pochiza zizindikiro za chikanga (atopic dermatitis; matenda apakhungu omwe amachititsa kuti khungu liume ndi kuyabwa ndipo nthawi zina limakhala ndi zotupa), mwa akulu ndi ana azaka 6 kapena kupitilira apo omwe sangathe kugwiritsa ntchito mankhwala ena chikhalidwe kapena yemwe chikanga sichinayankhe mankhwala ena. Amagwiritsidwanso ntchito limodzi ndi mankhwala ena oletsa kupuma, kupuma movutikira, kutsokomola, ndi chifuwa chifukwa cha mitundu ina ya mphumu mwa akulu ndi ana azaka 12 kapena kupitilira pomwe omwe sanazindikire ndi mankhwala ena. Jekeseni wa Dupilumab imagwiritsidwanso ntchito limodzi ndi mankhwala ena kuchiza matenda a rhinosinusitis ndi nasal polyposis (mphuno yothamanga, kutupa kwa sinus ndi / kapena mphuno yamphongo, yopanda kapena kununkhiza kapena kupweteka komanso kupsinjika pamaso) mwa akulu omwe zizindikiro zawo osalamulidwa ndi mankhwala ena. Jekeseni wa Dupilumab uli mgulu la mankhwala otchedwa monoclonal antibodies. Zimagwira ntchito poletsa zinthu zina m'thupi zomwe zimayambitsa zizindikiro za chikanga.

Jekeseni wa Dupilumab umabwera ngati jakisoni woyambira komanso cholembera chomwe chimakonda kubaya mozungulira (pansi pa khungu). Pofuna kuchiza chikanga mwa akulu, nthawi zambiri amapatsidwa ngati jakisoni awiri pamlingo woyamba, kenako jekeseni m'modzi milungu iwiri iliyonse. Pofuna kuchiza chikanga mwa ana azaka 6 mpaka 17, nthawi zambiri amaperekedwa ngati jakisoni awiri pa mlingo woyamba, kenako jekeseni m'modzi milungu iwiri kapena inayi kutengera kulemera kwa mwanayo. Pofuna kuchiza mphumu mwa akulu ndi ana azaka 12 kapena kupitilira apo, nthawi zambiri amapatsidwa ngati jakisoni awiri pamlingo woyamba, kenako jekeseni m'modzi milungu iwiri iliyonse. Pofuna kuchiza rhinosinusitis wamatenda amphongo mwa akulu, nthawi zambiri amaperekedwa ngati jakisoni m'masabata awiri aliwonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Gwiritsani ntchito jakisoni wa dupilumab ndendende momwe mwalangizira. Osabaya jakisoni wochulukirapo kapena kumubaya nthawi zambiri kuposa momwe adanenera.

Ngati mukugwiritsa ntchito dupilumab ndipo muli ndi mphumu, pitirizani kumwa kapena kugwiritsa ntchito mankhwala ena onse omwe dokotala wakupatsani kuti muchiritse mphumu yanu. Osasiya kumwa mankhwala anu aliwonse kapena kusintha mlingo wa mankhwala anu pokhapokha dokotala atakuuzani kuti muyenera. Jekeseni wa Dupilumab imathandiza kupewa matenda a mphumu koma siyimitsa kuukira kwa mphumu komwe kwayamba kale. Musagwiritse ntchito jakisoni wa dupilumab mukamakumana ndi mphumu. Dokotala wanu adzakupatsani inhaler yoti mugwiritse ntchito mukamakumana ndi mphumu.

Mutha kulandira mulingo wanu woyamba wa jekeseni wa dupilumab muofesi ya dokotala wanu. Pambuyo pake, dokotala wanu akhoza kukulolani inu kapena wothandizira kuti mumubayire jakisoni kunyumba. Musanagwiritse ntchito jekeseni wa dupilumab nokha nthawi yoyamba, werengani zambiri za wopanga kwa wodwala yemwe amabwera ndi mankhwala. Funsani dokotala wanu kapena wamankhwala kuti akuwonetseni kapena munthu amene akupatsani mankhwalawa kuti abayire.

Gwiritsani ntchito sirinji ndi cholembera kamodzi. Tayani masirinji ndi zolembera zomwe mwazigwiritsa ntchito m'mbale zosagwira. Lankhulani ndi dokotala wanu kapena wamankhwala za momwe mungatayire chidebe chosagwira mankhwala.

Ngati mukugwiritsa ntchito jakisoni woyambirira kapena cholembera chomwe chakhala mufiriji, ikani syringe pamalo osalala osachotsa kapu ya singano ndikulola kuti kutenthedwe kutentha (mphindi 30 za syringe yodzaza ndi 200 mg ndi mphindi 45 za 300 mg syringe kapena cholembera chodzaza) musanakonzekere kulandira mankhwala. Osayesa kutenthetsa mankhwalawo powotenthetsa mu microwave, ndikuwayika m'madzi otentha, kapena njira ina iliyonse.

Osamagwedeza sirinji kapena cholembera chomwe chili ndi dupilumab.

Nthawi zonse yang'anani yankho la dupilumab musanaibayize. Onetsetsani kuti tsiku lomaliza ladutsa komanso kuti madziwo ndiwowoneka bwino komanso opanda mtundu kapena wachikasu pang'ono. Madziwo sayenera kukhala ndi tinthu tomwe timawonekera. Musagwiritse ntchito sirinji kapena cholembera ngati chasweka kapena chophwanyika, ngati chatha kapena chazizira, kapena ngati madzi ali mitambo kapena ali ndi tinthu tating'onoting'ono.

Mutha kubaya jekeseni wa dupilumab kulikonse kutsogolo kwa ntchafu zanu (mwendo wapamwamba) kapena pamimba (m'mimba) kupatula mchombo wanu ndi dera la mainchesi 5 masentimita ozungulira. Wosamalira akabaya mankhwala, kumbuyo kwa mkono kungagwiritsidwenso ntchito. Kuti muchepetse mwayi wowawa kapena kufiira, gwiritsani ntchito tsamba lina la jakisoni aliyense. Osalowetsa malo omwe khungu ndi lofewa, lophwanyika, lofiira, kapena lolimba kapena komwe muli ndi zipsera kapena zotambasula.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanagwiritse ntchito jakisoni wa dupilumab,

• Uzani dokotala ndi wazamankhwala ngati muli ndi vuto la dupilumab, mankhwala ena aliwonse, kapena zosakaniza zilizonse za jekeseni wa dupilumab. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: mankhwala am'kamwa kapena opumira mu corticosteroid monga dexamethasone, methylprednisolone (Medrol), ndi prednisone (Rayos). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu ngati mwakhalapo ndi vuto la maso, kapena ngati muli ndi hookworm, roundworm, whipworm, kapena threadworm matenda (matenda omwe ali ndi mphutsi zomwe zimakhala mkati mwa thupi).Ngati mukulandira dupilumab yothandizira atropic dermatitis, uzani adotolo ngati muli ndi mphumu.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukamagwiritsa ntchito jakisoni wa dupilumab, itanani dokotala wanu.
• funsani dokotala wanu kuti muwone ngati mukufuna kulandira katemera uliwonse. Musakhale ndi katemera uliwonse mukamalandira chithandizo popanda kulankhula ndi dokotala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mwaphonya mlingo wa jekeseni wa dupilumab, jekeseni mlingo womwe mwaphonya mukangokumbukira ndikuyambiranso dongosolo lanu loyambirira. Komabe, ngati papita masiku opitilira 7 mutaphonya mlingo wanu, tulukani mlingo womwe mwaphonyawo ndikupitiliza dongosolo lanu lokhazikika. Musagwiritse ntchito mlingo wawiri kuti mupange omwe mwaphonya. Itanani dokotala wanu ngati mwaphonya mlingo ndikukhala ndi mafunso pazomwe mungachite.

Jekeseni wa Dupilumab itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kufiira kapena kupweteka pamalo obayira
• kupweteka kwa mmero
• zilonda mkamwa kapena pakamwa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• mavuto atsopano kapena owonjezeka a diso, kuphatikiza kupweteka kwa diso, kusawona bwino, maso (ofiira) kapena ofiira, zikope zofiira kapena zotupa, kapena kusintha kwa masomphenya
• zidzolo, kupuma movutikira, kutentha thupi, kupweteka pachifuwa, kumva zikhomo ndi singano, kapena kufooka mikono kapena miyendo

Ngati mukumane ndi izi, siyani kugwiritsa ntchito jakisoni wa dupilumab ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

• kutupa kwa nkhope, zikope, lilime, kapena mmero
• zotupa zam'mimba zotupa
• zovuta kumeza kapena kupuma
• zolimba pachifuwa kapena pakhosi
• kuyabwa
• zidzolo
• ming'oma
• kukomoka, chizungulire, kapena kumverera mopepuka
• kupweteka pamodzi
• osalala, olimba, otentha, ofiira komanso opweteka pakhungu
• malungo

Jekeseni wa Dupilumab itha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamagwiritsa ntchito mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe choyambirira chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosatheka kwa ana. Sungani jekeseni wa dupilumab mufiriji kapena kutentha kwa masiku 14. Osazizira. Sungani ma syringe ndi zolembera m'matoni awo oyambirira kuti muwateteze ku kuwala.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu.

Musalole kuti wina aliyense agwiritse ntchito mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zobwereza^®