Polatuzumab vedotin-piiq jekeseni

Zamkati

• Asanalandire jekeseni wa polatuzumab vedotin-piiq,
• Polatuzumab vedotin-piiq ingayambitse zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa m'gawo la HOW, itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:

Polatuzumab vedotin-piiq jekeseni imagwiritsidwa ntchito limodzi ndi bendamustine (Belrapzo, Treanda) ndi rituximab (Rituxan) mwa akulu kuti athetse mtundu wina wa non-Hodgkin's lymphoma (NHL; mtundu wa khansa womwe umayambira mumtundu wama cell oyera omwe nthawi zambiri fights infection) zomwe sizinasinthe kapena kusintha koma zimabweranso atalandira chithandizo ndi mankhwala ena awiri a chemotherapy. Polatuzumab vedotin-piiq ali mgulu la mankhwala otchedwa anti-drug conjugates. Zimagwira ntchito popha ma cell a khansa.

Polatuzumab vedotin-piiq imabwera ngati ufa wosakanikirana ndi madzi ndikubayidwa kudzera m'mitsempha (mumtsempha) ndi dokotala kapena namwino kuchipatala. Nthawi zambiri imaperekedwa mphindi 30 mpaka 90 patsiku 1 la masiku 21. Kuzungulira kumatha kubwerezedwa kasanu ndi kamodzi kapena kupitilira momwe dokotala akuwalimbikitsira. Kutalika kwa chithandizo chanu kumadalira momwe thupi lanu limayankhira ndi mankhwala komanso zovuta zomwe mumakumana nazo.

Mutha kukumana ndi zoopsa kapena zoopsa pamoyo wanu mukalandira jakisoni wa polatuzumab vedotin-piiq kapena mkati mwa maola 24 mulandila mlingo. Dokotala wanu angakuuzeni kuti mumwe mankhwala ena musanalandire mlingo wanu kuti muteteze izi. Dokotala kapena namwino adzakuyang'anirani kuti muwone momwe thupi lanu limayankhira polatuzumab vedotin-piiq. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira chithandizo cha jakisoni wa polatuzumab vedotin-piiq. Dokotala wanu akhoza kukupatsani mankhwala ena othandizira kupewa kapena kuthetsa izi. Ngati mukumane ndi izi pazomwe mungachite mukamudyetsedwa, uzani dokotala nthawi yomweyo: kuzizira, kuyabwa, ming'oma, malungo, kuthamanga, kuthamanga, kupuma movutikira, kupuma movutikira, kapena kupuma.

Dokotala wanu angafunikire kuchedwetsa chithandizo chanu, kusintha mlingo wanu, kapena kuyimitsa chithandizo chanu mukakumana ndi zovuta zina. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira mankhwala a polatuzumab vedotin-piiq.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jekeseni wa polatuzumab vedotin-piiq,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la polatuzumab vedotin-piiq, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu jekeseni wa polatuzumab vedotin-piiq. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: carbamazepine (Equetro, Tegretol, Teril); clarithromycin (Biaxin, mu PrevPac); Mankhwala ochizira HIV kuphatikiza efavirenz (Sustiva, ku Atripla), indinavir (Crixivan), nevirapine (Viramune), ritonavir (Norvir, ku Kaletra), ndi saquinavir (Invirase); itraconazole (Onmel, Sporanox), ketoconazole; nefazodone; phenobarbital, phenytoin (Dilantin, Phenytek); pioglitazone (Actos); rifabutin (Mycobutin); ndi rifampin (Rifadin, Rimactane, ku Rifamate). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi polatuzumab vedotin-piiq, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka St. John's Wort.
• Uzani dokotala wanu ngati muli ndi kachilombo kapena muli ndi matenda a chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Simuyenera kuyamba kulandira jakisoni wa polatuzumab vedotin-piiq mpaka kuyezetsa magazi kukuwonetsa kuti mulibe pakati. Ngati ndinu mayi amene amatha kutenga pakati, muyenera kugwiritsa ntchito njira yolerera yoyenerera mukamalandira chithandizo komanso kwa miyezi itatu mutalandira mankhwala. Ngati ndinu wamwamuna wokhala ndi mkazi yemwe angatenge mimba, muyenera kugwiritsa ntchito njira yolerera yoyenerera mukamalandira chithandizo komanso kwa miyezi isanu mutatha kumwa. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Ngati inu kapena mnzanu mutakhala ndi pakati mukalandira polatuzumab vedotin-piiq jekeseni, itanani dokotala wanu. Jekeseni ya Polatuzumab vedotin-piiq itha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Musamwe mkaka mukamamwa mankhwala komanso kwa miyezi iwiri mutatha kumwa.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukulandira jakisoni wa polatuzumab vedotin-piiq.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mwaphonya nthawi yoti mulandire polatuzumab vedotin-piiq, itanani dokotala wanu nthawi yomweyo.

Polatuzumab vedotin-piiq ingayambitse zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• kusanza
• chizungulire
• kusowa chilakolako
• kuonda
• kupweteka pamodzi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa m'gawo la HOW, itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:

• chisokonezo; chizungulire kapena kutayika bwino; kuvuta kulankhula kapena kuyenda; kapena kusintha kwa masomphenya
• dzanzi kapena kumva kulira kwa manja kapena mapazi; kapena kufooka kwa minofu, kupweteka, kapena kutentha
• kuvulaza kosavuta kapena kutuluka magazi; kutuluka magazi m'kamwa kapena m'mphuno; kapena magazi mkodzo kapena chopondapo
• nseru, kusanza, kutsegula m'mimba, ndi kutopa
• khungu lotuwa kapena kutopa kwachilendo kapena kufooka
• malungo, zilonda zapakhosi, kuzizira, kupweteka pokodza, ndi zizindikiro zina za matenda
• kutopa kwambiri; chikasu cha khungu kapena maso; kusowa chilakolako; mkodzo wamdima; kapena kupweteka kumtunda chakumanja kwam'mimba

Jekeseni wa Polatuzumab vedotin-piiq angayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti aone momwe thupi lanu likuyankhira jakisoni wa polatuzumab vedotin-piiq.

Funsani wamankhwala wanu mafunso aliwonse omwe mungakhale nawo okhudza jekeseni wa polatuzumab vedotin-piiq.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Polivy^®