Jekeseni wa Phenytoin
Zamkati
- Asanalandire jakisoni wa phenytoin,
- Phenytoin ingayambitse kuchuluka kwa shuga m'magazi anu. Lankhulani ndi dokotala wanu za zizindikiro za shuga wambiri wamagazi komanso zomwe muyenera kuchita mukakumana ndi izi.
- Jekeseni wa Phenytoin imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa mgulu la ZOYENERA, itanani dokotala wanu mwachangu:
- Zizindikiro za bongo zingaphatikizepo izi:
Mutha kukhala ndi kuthamanga kwa magazi koopsa kapena koopsa pamoyo kapena mtima wosakhazikika pomwe mukulandira jekeseni wa phenytoin kapena pambuyo pake. Uzani dokotala wanu ngati mwakhalapo ndi zingwe zosasinthasintha pamtima kapena zotchinga mtima (momwe magetsi samadutsidwira mwachizolowezi kuchokera kuzipinda zakumwamba zamkati mpaka kuzipinda zapansi). Dokotala wanu sangakonde kuti mulandire jakisoni wa phenytoin. Komanso, uzani dokotala ngati mwakhalapo ndi vuto la mtima kapena kuthamanga magazi. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: chizungulire, kutopa, kugunda kwamtima mosasinthasintha, kapena kupweteka pachifuwa.
Mukalandira mulingo uliwonse wa jakisoni wa phenytoin kuchipatala, ndipo adotolo kapena namwino adzakuyang'anirani mosamala mukalandira mankhwalawa komanso pambuyo pake.
Jakisoni wa Phenytoin amagwiritsidwa ntchito pochiza matenda amtundu wa tonic-clonic (omwe kale amadziwika kuti kugwidwa kwakukulu; kugwidwa komwe kumakhudza thupi lonse) ndikuchiza ndikupewa kugwidwa komwe kumatha kuyamba mkati kapena pambuyo pa opaleshoni ku ubongo kapena dongosolo lamanjenje. Jekeseni wa Phenytoin itha kugwiritsidwanso ntchito kuthana ndi mitundu ina ya khunyu mwa anthu omwe sangamwe phenytoin wamlomo. Phenytoin ali mgulu la mankhwala otchedwa anticonvulsants. Zimagwira ntchito pochepetsa magwiridwe antchito amagetsi muubongo.
Jakisoni wa Phenytoin amabwera ngati yankho (madzi) kuti alowemo jakisoni pang'onopang'ono (mumtsempha) ndi dokotala kapena namwino kuchipatala. Nthawi zambiri amabayidwa kamodzi pa maola 6 kapena 8 aliwonse.
Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.
Jekeseni wa Phenytoin imagwiritsidwanso ntchito kuwongolera kugunda kwamtima kosafunikira. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.
Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.
Asanalandire jakisoni wa phenytoin,
- uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la phenytoin, mankhwala ena a hydantoin monga ethotoin (Peganone) kapena fosphenytoin (Cerebyx), mankhwala ena aliwonse, kapena chilichonse chothandizira mu jakisoni wa phenytoin. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
- Uzani dokotala wanu ngati mukumwa delavirdine (Rescriptor). Dokotala wanu mwina sakufuna kuti mulandire jakisoni wa phenytoin ngati mukumwa mankhwalawa.
- Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: albendazole (Albenza); amiodarone (Nexterone, Pacerone); maanticoagulants ('oonda magazi') monga warfarin (Coumadin, Jantoven); mankhwala oletsa antifungal monga fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Onmel, Sporanox, Tolsura), miconazole (Oravig), posaconazole (Noxafil), ndi voriconazole (Vfend); ma antivirals ena monga efavirenz (Sustiva, ku Atripla), indinavir (Crixivan), lopinavir (ku Kaletra), nelfinavir (Viracept), ritonavir (Norvir, ku Kaletra), ndi saquinavir (Invirase); magazi; capecitabine (Xeloda); carboplatin; mankhwala enaake; chlordiazepoxide (Librium, ku Librax); mankhwala a cholesterol monga atorvastatin (Lipitor, mu Caduet), fluvastatin (Lescol), ndi simvastatin (Zocor, ku Vytorin); cisplatin; clozapine (Fazaclo, Versacloz); cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); diazoxide (Proglycem); digoxin (Lanoxin); disopyramide (Norpace); disulfiram (Antabuse); doxorubicin (Doxil); doxycycline (Acticlate, Doryx, Monodox, Oracea, Vibramycin); fluorouril; fluoxetine (Prozac, Sarafem, mu Symbyax, ena); fluvoxamine (Luvox); kupatsidwa folic acid; fosamprenavir (Lexiva); furosemide (Lasix); H2 otsutsa monga cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), ndi ranitidine (Zantac); njira zolerera za mahomoni (mapiritsi olera, zigamba, mphete, kapena jakisoni); mankhwala othandizira mahomoni (HRT); irinotecan (Camptosar); isoniazid (Laniazid, ku Rifamate, ku Rifater); mankhwala a matenda amisala ndi nseru; Mankhwala ena ogwidwa monga carbamazepine (Carbatrol, Equetro, Tegretol, ena), ethosuximide (Zarontin), felbamate (Felbatol), lamotrigine (Lamictal), methsuximide (Celontin), oxcarbazepine (Trilepta, Oxtellar XR), phenobar XR), phenobar ), ndi valproic acid (Depakene); methadone (Dolophine, Methadose); methotrexate (Otrexup, Rasuvo, Trexall, Xatmep); methylphenidate (Daytrana, Concerta, Metadate, Ritalin); mexiletine; nifedipine (Adalat, Procardia), nimodipine (Nymalize), nisoldipine (Sular); omeprazole (Prilosec); oral steroids monga dexamethasone, methylprednisolone (Medrol), prednisolone, ndi prednisone (Rayos); paclitaxel (Abraxane, Taxol); paroxetine (Paxil, Pexeva); praziquantel (Biltricide); quetiapine (Seroquel); quinidine (mu Nuedexta); kuperekanso; rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); kupweteka kwa salicylate kumachepetsa monga aspirin, choline magnesium trisalicylate, choline salicylate, diflunisal, magnesium salicylate (Doan's, ena), ndi salsalate; mankhwala opatsirana (Zoloft); mankhwala a sulfa; teniposide; theophylline (Elixophyllin, Theo-24, Theochron); ticlopidine; tolbutamide; trazodone; verapamil (Calan, Verelan, ku Tarka); kachilombo (Sabril); ndi vitamini D. Dokotala wanu angafunike kusintha mlingo wa mankhwala anu kapena kukuyang'anirani mosamala za zotsatirapo zake.
- uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
- uzani dokotala wanu ngati mwakhalapo ndi vuto la chiwindi mukamamwa phenytoin. Dokotala wanu mwina sakufuna kuti mulandire jakisoni wa phenytoin.
- Uzani dokotala wanu ngati mumamwa kapena mwakhala mukumwapo mowa wambiri. Uzani dokotala wanu ngati mwayezetsa labotale komwe akuti muli ndi chiopsezo chobadwa nacho chomwe chimakupangitsani kuti mutha kukhala ndi vuto lalikulu pakhungu ndi phenytoin. Komanso, uzani dokotala ngati mwakhalapo ndi matenda a shuga, porphyria (momwe zinthu zina zachilengedwe zimakhalira mthupi ndipo zimatha kupweteketsa m'mimba, kusintha kwamaganizidwe kapena machitidwe, kapena zizindikilo zina), milingo yotsika ya albin magazi, kapena matenda a impso kapena chiwindi.
- Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Simuyenera kutenga pakati mukalandira phenytoin. Lankhulani ndi dokotala wanu za njira zothandiza zolerera zomwe mungagwiritse ntchito mukamachiza. Mukakhala ndi pakati mukalandira phenytoin, itanani dokotala wanu. Phenytoin itha kuvulaza mwana wosabadwayo.
- ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukulandira phenytoin.
- Muyenera kudziwa kuti mankhwalawa amatha kuyambitsa chizungulire, kugona, komanso mavuto chifukwa chothandizana. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
- lankhulani ndi dokotala wanu zakumwa koyenera kwa mowa mukamamwa mankhwalawa.
- lankhulani ndi dokotala wanu za njira yabwino yosamalirira mano, m'kamwa, ndi pakamwa mukamachiza phenytoin. Ndikofunikira kuti musamalire pakamwa panu moyenera kuti muchepetse chiwopsezo cha kuwonongeka kwa chingamu chifukwa cha phenytoin.
Phenytoin ingayambitse kuchuluka kwa shuga m'magazi anu. Lankhulani ndi dokotala wanu za zizindikiro za shuga wambiri wamagazi komanso zomwe muyenera kuchita mukakumana ndi izi.
Jekeseni wa Phenytoin imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- kuvuta kugona kapena kugona
- mayendedwe osalamulirika amaso
- kusuntha kwa thupi
- kutayika kwa mgwirizano
- chisokonezo
- mawu osalankhula
- mutu
- amasintha momwe mumamvera kukoma
- kudzimbidwa
- kukula kosafunika kwa tsitsi
- Kukula kwa nkhope
- kukulitsa kwa milomo
- kuchuluka kwa m'kamwa
- kupweteka kapena kupindika kwa mbolo
Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa mgulu la ZOYENERA, itanani dokotala wanu mwachangu:
- kutupa, kusintha, kapena kupweteka pamalo obayira
- zidzolo
- ming'oma
- kuyabwa
- kutupa kwa maso, nkhope, mmero, lilime, mikono, manja, akakolo, kapena miyendo yakumunsi
- kuvuta kupuma kapena kumeza
- ukali
- zotupa zotupa
- nseru
- kusanza
- chikasu cha khungu kapena maso
- kupweteka kumtunda chakumanja kwam'mimba
- kutopa kwambiri
- kuvulaza kapena kutuluka mwachilendo
- mawanga ofiira kapena ofiirira pakhungu
- kusowa chilakolako
- zizindikiro ngati chimfine
- malungo, zilonda zapakhosi, zotupa, zilonda mkamwa, kapena mabala osavuta, kapena kutupa kwa nkhope
Jekeseni wa Phenytoin imatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.
Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).
Kutenga phenytoin kumachulukitsa chiopsezo choti mutha kukhala ndi vuto ndi ma lymph node anu kuphatikiza matenda a Hodgkin's (khansa yomwe imayamba m'mitsempha). Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa pochiza matenda anu.
Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.
Zizindikiro za bongo zingaphatikizepo izi:
- mayendedwe osalamulirika amaso
- kutayika kwa mgwirizano
- mawu odekha kapena osalankhula
- kutopa
- kusawona bwino
- kugwedezeka kosalamulirika kwa gawo lina la thupi
- nseru
- kusanza
Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone kuyankha kwanu ku jakisoni wa phenytoin.
Musanayesedwe mu labotale, uzani adotolo ndi omwe akuwalembera kuti mukulandira jekeseni wa phenytoin.
Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.
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Idasinthidwa Komaliza - 12/15/2019