Tazemetostat

Zamkati

• Musanatenge tazemetostat,
• Tazemetostat angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

Tazemetostat imagwiritsidwa ntchito pochizira epithelioid sarcoma (khansa yofewa, yofooka pang'onopang'ono) mwa akulu ndi ana azaka 16 kapena kupitilira yomwe yafalikira kumatenda oyandikira kapena mbali zina za thupi ndipo sangathe kuchiritsidwa bwino ndi opareshoni. Amagwiritsidwanso ntchito kuthana ndi mitundu ina ya follicular lymphoma (FL; mtundu wa khansa womwe umayambira m'maselo oyera amwazi) mwa akulu omwe khansa yomwe yabwerera kapena sinayankhe pafupifupi mankhwala ena awiri. Tazemetostat imagwiritsidwanso ntchito pochiza follicular lymphoma mwa achikulire omwe abwerera kapena sanayankhe mankhwala ngati kulibe njira zina zamankhwala zomwe zingapezeke. Tazemetostat ali mgulu la mankhwala otchedwa EZH2 inhibitors. Zimathandiza kuletsa kufalikira kwa maselo a khansa.

Tazemetostat imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kawiri patsiku kapena wopanda chakudya. Tengani tazemetostat mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani tazemetostat ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Ngati musanza mutangotenga tazemetostat, musamwe mlingo wina. Pitirizani dongosolo lanu lokhazikika.

Dokotala wanu akhoza kuyimitsa chithandizo chanu kwakanthawi kapena kosatha kapena amachepetsa tazemetostat mlingo wanu kutengera zovuta zomwe mumakumana nazo. Onetsetsani kuti mwalankhula ndi dokotala za momwe mukumvera mukamalandira chithandizo. Osasiya kumwa tazemetostat osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge tazemetostat,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi tazemetostat, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a tazemetostat. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ena omwe simukupatsidwa, mavitamini, ndi zowonjezera zakudya zomwe mukumwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: aprepitant (Emend), carbamazepine (Carbatrol, Teril, ena), clarithromycin (Biaxin, ku Prevpac), diltiazem (Cardizem, Cartia, Diltzac, ena), efavirenz (Sustiva, ku Atripla), erythromycin (EES, PCE, ena), njira zolerera za mahomoni (mapiritsi oletsa kubala, zigamba, mphete, kapena jakisoni), indinavir (Crixivan), itraconazole (Onmel, Sporanox), ketoconazole, modafinil (Provigil), nefazodone, nelfinavir (Viracept), nevirapine (Viramune), phenobarbital, phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, ku Rifamate), ritonavir (Norvir, ku Kaletra), saquinavir (Fortovase, Invirase), , Verelan). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi tazemetostat, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi matenda a chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena konzekerani kukhala ndi mwana. Tazemetostat itha kusokoneza zochita za njira zolerera za mahomoni (mapiritsi oletsa kubala, zigamba, mphete, zopangira, kapena jakisoni), chifukwa chake simuyenera kugwiritsa ntchito njirayi yokhayo yolerera mukamalandira chithandizo. Ngati ndinu wamkazi, muyenera kuyezetsa asanayambe kulandira chithandizo ndikugwiritsa ntchito njira yolera yopanda mahomoni (chida chomwe chimalepheretsa umuna kulowa muchiberekero monga kondomu) kuti muteteze mimba mukamalandira chithandizo komanso kwa miyezi 6 mlingo womaliza. Ngati ndinu wamwamuna, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira yolerera yoyenerera mukamalandira chithandizo komanso kwa miyezi itatu mutalandira mankhwala. Funsani dokotala wanu kuti akuthandizeni kusankha njira yolerera yomwe ingagwire ntchito kwa inu kapena mnzanu. Ngati inu kapena mnzanu muli ndi pakati mukatenga tazemetostat, itanani dokotala wanu mwachangu. Tazemetostat ikhoza kuvulaza mwanayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa mankhwala komanso kwa sabata limodzi mutapatsidwa mankhwala omaliza.

Musadye zipatso zamphesa kapena kumwa madzi amphesa mukamamwa mankhwalawa.

Pitani muyezo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Tazemetostat angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kusowa chilakolako
• nseru
• kusanza
• kudzimbidwa
• kutsegula m'mimba
• kupweteka m'mimba
• kuonda
• chifuwa
• mutu
• kutopa
• kupweteka kwa minofu, fupa, kapena molumikizana

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• kutopa, kuphwanya mosavuta, malungo, kupweteka kwa mafupa, kapena khungu lotumbululuka
• magazi osazolowereka
• matenda akhungu
• kupuma movutikira

Tazemetostat imatha kubweretsa chiopsezo chowonjezeka chokhala ndi khansa. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa.

Tazemetostat ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Nthawi zina, dokotala wanu amalamula kuyesedwa kwa labu musanayambe mankhwala anu kuti muwone ngati khansa yanu ingathe kuthandizidwa ndi tazemetostat. Dokotala wanu amathanso kuyitanitsa mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira tazemetostat.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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