Elagolix, Estradiol, ndi Norethindrone

Zamkati

• Musanatenge kuphatikiza kwa elagolix, estradiol, ndi norethindrone,
• Elagolix, estradiol, ndi norethindrone zitha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo:

Mankhwala okhala ndi estradiol ndi norethindrone amatha kuwonjezera chiopsezo cha matenda a mtima, sitiroko, ndi magazi m'mapapu ndi miyendo. Uzani dokotala wanu ngati mumasuta komanso ngati mwadwalapo kapena munagwapo mtima; sitiroko; magazi aundana m'miyendo mwanu, m'mapapu kapena m'maso; matenda a valavu ya mtima; kuthamanga kapena kusakhazikika kwamtima; thrombophilia (momwe magazi amaundana mosavuta); mutu waching'alang'ala; kuthamanga kwa magazi; kuchuluka kwama cholesterol kapena mafuta; kapena matenda ashuga omwe akhudza kuyenda kwanu. Dokotala wanu angakuuzeni kuti simuyenera kumwa mankhwalawa ngati mwakhalapo kapena mwakhalapo ndi izi. Ngati mukuchitidwa opaleshoni kapena mugona pabedi, dokotala wanu angafune kuti musiye kumwa mankhwala osachepera 4 mpaka 6 milungu isanachitike opaleshoniyo kapena bedi.

Ngati mukumane ndi zotsatirazi, itanani dokotala nthawi yomweyo: mwadzidzidzi, mutu wopweteka kwambiri; kutaya mwadzidzidzi pang'ono kapena kwathunthu; masomphenya awiri; mavuto a kulankhula; chizungulire kapena kukomoka; kufooka kapena kufooka kwa mkono kapena mwendo; kuphwanya kupweteka pachifuwa kapena kulemera pachifuwa; kutsokomola magazi; kupuma mwadzidzidzi; kapena kupweteka, kukoma, kapena kufiira mwendo umodzi.

Dokotala wanu kapena wamankhwala amakupatsirani pepala lazidziwitso zaopanga (Medication Guide) mukayamba chithandizo ndi elagolix, estradiol, ndi norethindrone ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Lankhulani ndi dokotala wanu za chiwopsezo chotenga elagolix, estradiol, ndi norethindrone.

Kuphatikiza kwa elagolix, estradiol, ndi norethindrone amagwiritsidwa ntchito pochiza kutuluka magazi msambo komwe kumayambitsidwa ndi uterine fibroids (zopitilira m'chiberekero chomwe si khansa). Elagolix ali mgulu la mankhwala otchedwa gonadotropin-release hormone (GnRH) antagonist receptor. Estradiol ali mgulu la mankhwala otchedwa estrogen hormone. Norethindrone ali mgulu la mankhwala otchedwa progestins. Elagolix imagwira ntchito pochepetsa kuchuluka kwa mahomoni ena m'thupi. Estradiol imagwira ntchito m'malo mwa estrogen yomwe nthawi zambiri imapangidwa ndi thupi. Norethindrone imagwira ntchito poletsa chiberekero kukula kwa chiberekero ndikupangitsa chiberekero kutulutsa mahomoni ena.

Kuphatikiza kwa elagolix, estradiol, ndi norethindrone kumabwera ngati makapisozi oti atenge pakamwa. Nthawi zambiri amatengedwa wopanda chakudya kawiri tsiku lililonse kwa miyezi 24. Mankhwalawa amabwera phukusi lomwe limakhala ndi masiku 28 akumwa. Phukusi lililonse la mlungu uliwonse limakhala ndi mitundu iwiri ya makapisozi, 7 okhala ndi elagolix, estradiol, ndi norethindrone (makapisozi achikaso ndi oyera) ndi 7 okhala ndi elagolix (makapisozi abuluu ndi oyera). Tengani elagolix, estradiol, ndi norethindrone (kapisozi 1) m'mawa uliwonse kenako mutenge elagolix (kapisozi 1) usiku uliwonse. Tengani elagolix, estradiol, ndi norethindrone mozungulira nthawi yomweyo tsiku lililonse.Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani elagolix, estradiol, ndi norethindrone ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu akhoza kukupatsani mankhwala othandizira calcium ndi vitamini D kuti mutenge mukamalandira chithandizo. Muyenera kumwa zowonjezerazi monga mwadokotala wanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge kuphatikiza kwa elagolix, estradiol, ndi norethindrone,

• Uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la elagolix, estradiol, norethindrone, aspirin, tartrazine (utoto wachikasu wopezeka m'mankhwala ena), mankhwala ena aliwonse, kapena zosakaniza zilizonse mu elagolix, estradiol, ndi makapisozi a norethindrone. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu ngati mukumwa cyclosporine (Gengraf, Neoral, Sandimmune) kapena gemfibrozil (Lopid). Dokotala wanu mwina angakuuzeni kuti musatenge kuphatikiza kwa elagolix, estradiol, ndi norethindrone ngati mukumwa mankhwala amodzi kapena angapo.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: digoxin (Lanoxin); ketoconazole; levothyroxine (Levoxyl, Synthroid, Tirosint, ena); midazolam (Nayzilam); phenytoin (Dilantin, Phenytek); proton pump inhibitors monga dexlansoprazole (Dexilant), esomeprazole (Nexium, ku Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec, ku Talicia, ku Yosprala, ku Zegred), pantoprazole (Protonix), ndi rabeprazole (Aciphex) rifampin (Rifadin, mu Rifamate, ku Rifater); rosuvastatin (Crestor); ndi steroids monga dexamethasone (Hemady), methylprednisolone (Medrol), prednisone, ndi prednisolone (Orapred ODT, Pediapred, Prelone). Komanso, uzani dokotala wanu kapena wamankhwala ngati mukumwa mavitamini kapena mchere wokhala ndi chitsulo. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi elagolix, estradiol, ndi norethindrone, onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi khansa ya m'mawere; khansara ya chiberekero, nyini, kapena zotengera za chiberekero; kufooka kwa mafupa (komwe mafupa amakhala ochepa thupi ndipo amatha kuthyoka); magazi osadziwika osadziwika amaliseche; zotumphukira mitsempha matenda (osauka kufalikira kwa mitsempha); Matenda a mtima kapena chiwindi kapena vuto lina lililonse la chiwindi. Dokotala wanu mwina angakuuzeni kuti musatenge kuphatikiza kwa elagolix, estradiol, ndi norethindrone.
• uzani dokotala wanu ngati mwakhalapo ndi mafupa osweka; kukhumudwa, kuda nkhawa, kusintha kosazolowereka pamakhalidwe kapena malingaliro, kapena malingaliro okhudza kudzipha; matenda a ndulu; jaundice (chikasu chachikopa kapena maso); mavuto a chithokomiro; kapena kusakwanira kwa adrenal (momwe matumbo a adrenal samatulutsa mahomoni okwanira ofunikira pakuchita zofunikira mthupi).
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Musatenge elagolix, estradiol, ndi norethindrone ngati muli ndi pakati kapena mukuganiza kuti muli ndi pakati. Dokotala wanu adzayesa kutenga mimba asanayambe kumwa mankhwala kapena angakuuzeni kuti muyambe kumwa mankhwala pasanathe masiku asanu ndi awiri mutangoyamba kusamba kuti mutsimikizire kuti mulibe pakati mukatenga elagolix, estradiol, ndi norethindrone. Elagolix, estradiol, ndi norethindrone zitha kusokoneza zochita za njira zina zakulera zamahomoni, chifukwa chake simuyenera kugwiritsa ntchito njirayi yokhayo yolerera mukamalandira chithandizo. Muyenera kugwiritsa ntchito njira yodalirika yopanda mahomoni yoletsa kupewa kubereka mukamalandira chithandizo komanso kwa sabata limodzi mutapatsidwa mankhwala omaliza. Funsani dokotala wanu kuti akuthandizeni kusankha njira yolerera yomwe ingakuthandizeni. Mukakhala ndi pakati mukatenga elagolix, estradiol, ndi norethindrone, itanani dokotala wanu mwachangu. Elagolix, estradiol, ndi norethindrone zitha kuvulaza mwana wosabadwayo.
• muyenera kudziwa kuti thanzi lanu lamisala lingasinthe m'njira zosayembekezereka ndipo mutha kudzipha (kuganiza zodzipweteka kapena kudzipha nokha kapena kukonzekera kapena kuyesa kutero) mukamamwa elagolix, estradiol, ndi norethindrone. Inu, banja lanu, kapena amene amakusamalirani muyenera kuyimbira dokotala nthawi yomweyo mukakumana ndi izi: kukwiya kwatsopano kapena kukulira, nkhawa, kapena kukhumudwa; kuyankhula kapena kuganiza zofuna kudzipweteka kapena kudzipha; kudzipatula kwa abwenzi ndi abale; kutanganidwa ndi imfa ndi kufa; kapena kusintha kwina kulikonse pamakhalidwe kapena malingaliro. Onetsetsani kuti banja lanu kapena amene akukusamalirani akudziwa zomwe zingakhale zovuta kuti athe kuyimbira dokotala ngati mukulephera kupeza chithandizo chanokha.

Musadye zipatso zamphesa kapena kumwa madzi amphesa mukamamwa mankhwalawa.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati papitilira maola 4 kuchokera pa mlingo wanu womaliza, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Elagolix, estradiol, ndi norethindrone zitha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutayika tsitsi kapena kupatulira tsitsi
• kutentha (kutentha kwadzidzidzi kwa kutentha pang'ono kapena kutentha kwambiri kwa thupi)
• kusintha kwa msambo (kutuluka magazi mosalekeza kapena kuwona, kutuluka pang'ono kapena kusataya magazi, kutsika kwakanthawi)
• mutu
• kunenepa
• kupweteka pamodzi
• kusintha kwa chikhumbo chakugonana
• Kusinza kapena kutopa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• chikasu cha khungu kapena maso
• kuvulaza kapena kutuluka mwachilendo
• kusowa chilakolako
• kutopa kwambiri, kufooka, kapena kusowa mphamvu
• mkodzo wamtundu wakuda
• chopondapo chowala
• kupweteka kumtunda chakumanja kwam'mimba
• nseru
• kusanza
• kutupa kwa manja, mapazi, kapena miyendo yakumunsi

Kuphatikiza kwa elagolix, estradiol, ndi norethindrone kumatha kuyambitsa kapena kukulitsa kufooka kwa mafupa. Ikhoza kuchepetsa kuchuluka kwa mafupa anu ndikuwonjezera mwayi wamafupa osweka ndi zophulika. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa.

Elagolix, estradiol, ndi norethindrone zitha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• nseru
• kusanza
• chikondi cha m'mawere
• kupweteka m'mimba
• Kusinza kapena kutopa
• magazi ukazi

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira elagolix, estradiol, ndi norethindrone.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Oriahnn^®

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