Filgrastim jekeseni

Zamkati

• Musanagwiritse ntchito jekeseni wa filgrastim,
• Filgrastim zopangira jekeseni zingayambitse zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

Jekeseni wa Filgrastim, jakisoni wa filgrastim-aafi, jakisoni wa filgrastim-sndz, ndi jakisoni wa tbo-filgrastim ndi mankhwala a biologic (mankhwala opangidwa kuchokera kuzinthu zamoyo). Biosimilar filgrastim-aafi jekeseni, jekeseni wa filgrastim-sndz, ndi jakisoni wa tbo-filgrastim ndi ofanana kwambiri ndi jekeseni wa filgrastim ndipo amagwira ntchito chimodzimodzi ndi jekeseni wa filgrastim mthupi. Chifukwa chake, mawu akuti mankhwala a jekeseni a filgrastim adzagwiritsidwa ntchito kuyimira mankhwalawa pazokambirana izi.

Mankhwala opangidwa ndi jekeseni wa Filgrastim (Granix, Neupogen, Nivestym, Zarxio) amagwiritsidwa ntchito pochepetsa mwayi wopezeka ndi anthu omwe ali ndi khansa ya myeloid (khansa yomwe siyikuphatikizira m'mafupa) ndipo akumalandira mankhwala a chemotherapy omwe amachepetsa ma neutrophils ( mtundu wa selo yamagazi yofunikira kulimbana ndi matenda). Mankhwala opangira jekeseni wa Filgrastim (Neupogen, Nivestym, Zarxio) amagwiritsidwanso ntchito kuthandizira kuonjezera kuchuluka kwa maselo oyera amwazi, ndikuchepetsa kutalika kwa nthawi ndi malungo mwa anthu omwe ali ndi khansa ya myeloid (AML; mtundu wa khansa yamagazi oyera) omwe akulandira chithandizo ndi mankhwala a chemotherapy.Mankhwala opangira jekeseni wa Filgrastim (Neupogen, Nivestym, Zarxio) amagwiritsidwanso ntchito kwa anthu omwe akuwonekeratu m'mafupa, mwa anthu omwe ali ndi neutropenia yayikulu (momwe mulinso ma neutrophil ochepa m'magazi), ndikukonzekera magazi Leukapheresis (mankhwala omwe maselo ena amachotsedwa mthupi. Jekeseni ya Filgrastim (Neupogen) imagwiritsidwanso ntchito kuonjezera mwayi wopulumuka mwa anthu omwe ali ndi poizoni wowopsa wa radiation, zomwe zitha kupangitsa kuti zikhale zowopsa komanso zowopsa pamoyo Filgrastim ali mgulu la mankhwala omwe amatchedwa kuti zinthu zoyambitsa colony.Amagwira ntchito pothandiza thupi kupanga ma neutrophil ambiri.

Filgrastim jekeseni mankhwala amabwera ngati yankho (madzi) m'mitsuko ndi ma syringe oyikiratu obayira pansi pa khungu kapena mumtsempha. Nthawi zambiri amaperekedwa kamodzi patsiku, koma zopangira mafiligastim (Neupogen, Nivestym, Zarxio) amatha kupatsidwa kawiri patsiku akagwiritsa ntchito kuchiza matenda osachiritsika a neutropenia. Kutalika kwa chithandizo chanu kumadalira momwe muliri komanso momwe thupi lanu limayankhira ndi mankhwalawo.

Ngati mukugwiritsa ntchito mankhwala opangira mankhwala a filgrastim kuti muchepetse chiopsezo chotenga matenda, kuchepetsa nthawi ndi malungo, kapena kuwonjezera kuchuluka kwa maselo oyera am'magazi pa chemotherapy, mudzalandira mankhwala anu oyamba pasanathe maola 24 mutalandira mankhwala chemotherapy, ndipo apitiliza kulandira mankhwalawa tsiku lililonse kwa milungu iwiri kapena mpaka kuchuluka kwama cell anu abwerere mwakale. Ngati mukugwiritsa ntchito mankhwala a jekeseni wa filgrastim kuti muchepetse chiopsezo chotenga kachiromboka mukamayika mafuta m'mafupa, mudzalandira mankhwalawa pasanathe maola 24 mutalandira chemotherapy komanso patadutsa maola 24 mafupa aloledwa. Ngati mukugwiritsa ntchito mankhwala a jekeseni wa filgrastim kukonzekera magazi anu mu leukapheresis, mudzalandira mankhwala anu osachepera masiku 4 isanafike leukapheresis yoyamba ndipo mupitiliza kulandira mankhwalawa mpaka leukapheresis yomaliza. Ngati mukugwiritsa ntchito jekeseni wa filgrastim kuchiza matenda osachiritsika a neutropenia, mungafunikire kugwiritsa ntchito mankhwalawa kwakanthawi. Ngati mukugwiritsa ntchito jekeseni wa filgrastim chifukwa mwakhala mukuwonongeka ndi radiation, dokotala wanu amakakuyang'anirani mosamala ndipo kutalika kwa mankhwala anu kumadalira momwe thupi lanu limayankhira ndi mankhwalawo. Osasiya kugwiritsa ntchito jekeseni wa filgrastim osalankhula ndi dokotala.

Mankhwala opatsirana pogonana angakupatseni namwino kapena wothandizira ena, kapena mungauzidwe kuti mubayire mankhwalawo pansi pa khungu kunyumba. Ngati inu kapena wosamalira mudzakhala mukubaya mankhwala a filgrastim kunyumba, wothandizira zaumoyo adzakuwonetsani inu kapena amene amakusamalirani momwe mungabayire mankhwalawo. Onetsetsani kuti mukumvetsetsa izi. Funsani wothandizira zaumoyo wanu ngati muli ndi mafunso. Gwiritsani ntchito mankhwala a jekeseni wa filgrastim monga momwe adauzira. Osamagwiritsa ntchito zocheperako kapena kuzigwiritsa ntchito pafupipafupi kuposa momwe adanenera dokotala.

Musagwedeze mbale kapena majekeseni okhala ndi mankhwala a filgrastim. Nthawi zonse yang'anani zopangira jekeseni wa filgrastim musanafike jakisoni. Musagwiritse ntchito ngati tsiku lomaliza latha, kapena ngati njira ya filgrastim ili ndi tinthu tating'onoting'ono kapena ikuwoneka ngati ya thovu, mitambo, kapena yopindika.

Gwiritsani ntchito sirinji kapena botolo lililonse kamodzi. Ngakhale pangakhale yankho lomwe latsala mu syringe kapena botolo, musagwiritsenso ntchito. Kutaya singano zogwiritsidwa ntchito, ma syringe, ndi Mbale mu chidebe chosagundika. Lankhulani ndi dokotala wanu kapena wamankhwala za momwe mungatayire chidebe chosagwira mankhwala.

Dokotala wanu akhoza kukuyambitsani pamlingo wochepa wa mankhwala a jekeseni wa filgrastim ndikuwonjezera mlingo wanu pang'onopang'ono. Dokotala wanu amathanso kuchepetsa mlingo wanu, kutengera momwe thupi lanu limachitikira ndi mankhwalawo.

Ngati mukugwiritsa ntchito jekeseni wa filgrastim kuchiza matenda osachiritsika a neutropenia, muyenera kudziwa kuti mankhwalawa azitha kuwongolera matenda anu koma sangakuchiritseni. Pitirizani kugwiritsa ntchito mankhwala a jekeseni ya filgrastim ngakhale mukumva bwino. Osasiya kugwiritsa ntchito jekeseni wa filgrastim osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwala opangidwa ndi jekeseni wa Filgrastim nthawi zina amagwiritsidwa ntchito pochiza mitundu ina ya matenda a myelodysplastic (gulu la mafupa omwe mafupa am'magazi amatulutsa maselo am'magazi omwe samangika bwino ndipo samatulutsa maselo amwazi wathanzi) ndi kuperewera kwa magazi m'thupi (aplastic anemia) samapanga maselo amwazi okwanira). Mankhwala opangidwa ndi jekeseni wa Filgrastim nthawi zina amagwiritsidwanso ntchito kuchepetsa mwayi wotenga kachilombo kwa anthu omwe ali ndi kachilombo ka HIV kapena anthu omwe akumwa mankhwala ena omwe amachepetsa ma neutrophils. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanagwiritse ntchito jekeseni wa filgrastim,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi filgrastim, pegfilgrastim (Neulasta), mankhwala ena aliwonse kapena zinthu zilizonse zopangira mankhwala a filgrastim. Komanso muuzeni adotolo ngati inu kapena munthu amene mukubaya jekeseni wa mankhwala a filgrastim (Neupogen, Zarxio) sagwirizana ndi latex.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati mukukumana ndi mankhwala a radiation komanso ngati mwakhalapo kapena mwakhalapo ndi matenda a khansa ya m'magazi (matenda opitilira pang'onopang'ono momwe maselo oyera oyera amapangidwira m'mafupa), kapena myelodysplasia (mavuto am'mafupa am'magazi) omwe atha kukhala khansa ya m'magazi).
• auzeni adotolo ngati muli ndi matenda a sickle cell (matenda amwazi omwe angayambitse mavuto owawa, kuchuluka kwama cell ofiira ofiira, matenda, komanso kuwonongeka kwa ziwalo zamkati). Ngati muli ndi matenda a sickle cell, mutha kukhala ndi vuto lalikulu mukamalandira mankhwala opangira mankhwala a filgrastim. Imwani madzi ambiri mukamamwa mankhwala a filgrastim ndipo muimbireni foni nthawi yomweyo ngati muli ndi vuto la khungu lanu mukamamwa mankhwala.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukamagwiritsa ntchito jekeseni wa filgrastim itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukugwiritsa ntchito mankhwala a filgrastim.
• Muyenera kudziwa kuti mankhwala a jekeseni a filgrastim amachepetsa chiopsezo chotenga matenda, koma samateteza matenda onse omwe amayamba pakachitika chemotherapy kapena pambuyo pake. Itanani dokotala wanu ngati mukudwala matenda otentha thupi; kuzizira; zidzolo; chikhure; kutsegula m'mimba; kapena kufiira, kutupa, kapena kupweteka kozungulira pamalonda kapena pachilonda.
• mukapeza mankhwala a filgrastim pakhungu lanu, sambani malowo ndi sopo. Ngati mankhwala a filgrastim alowa m'diso lako, tsukutsani diso lanu ndi madzi.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mukubaya jekeseni wa mankhwala a filgrastim kunyumba, lankhulani ndi dokotala wanu zomwe muyenera kuchita mukaiwala kubaya mankhwalawo panthawi yake.

Filgrastim zopangira jekeseni zingayambitse zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kufiira, kutupa, kufinya, kuyabwa kapena chotupa pamalo pomwe munabayira mankhwala
• fupa, olowa, kumbuyo, mkono, mwendo, mkamwa, mmero, kapena kupweteka kwa minofu
• mutu
• zidzolo
• kudzimbidwa
• kutsegula m'mimba
• nseru
• kusanza
• kusowa chilakolako
• kuvuta kugona kapena kugona
• kuchepa kwa kukhudza
• kutayika tsitsi
• mwazi wa m'mphuno
• kutopa, kusowa mphamvu
• osamva bwino
• chizungulire

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

• kupweteka kumtunda chakumanzere kwa m'mimba kapena kunsonga kwa phewa lamanzere
• malungo, kupuma movutikira, kupuma movutikira, kupuma mwachangu
• kuvuta kupuma, kutsokomola magazi
• malungo, kupweteka m'mimba, kupweteka msana, kumva kusakhala bwino
• kutupa kwa m'mimba kapena kutupa kwina, kuchepa pokodza, kupuma movutikira, chizungulire, kutopa
• zidzolo, ming'oma, kuyabwa, kutupa kwa nkhope, maso, kapena pakamwa, kupuma, kupuma movutikira
• magazi osazolowereka kapena mabala, zipsera pansi pa khungu, khungu lofiira
• Kuchepetsa kukodza, mkodzo wamdima kapena wamagazi, kutupa kwa nkhope kapena akakolo
• kupweteka kofulumira, mwachangu, kapena pafupipafupi

Anthu ena omwe amagwiritsa ntchito jakisoni wa filgrastim kuchiza matenda osachiritsika a neutropenia adayamba khansa ya m'magazi (khansa yomwe imayamba m'mafupa) kapena kusintha kwama cell am'mafupa omwe amawonetsa kuti leukemia itha kudzuka mtsogolo. Anthu omwe ali ndi matenda osachiritsika a neutropenia amatha kudwala khansa ya m'magazi ngakhale atakhala kuti sagwiritsa ntchito filgrastim. Palibe chidziwitso chokwanira chodziwitsa ngati mankhwala a jekeseni wa filgrastim angapangitse mwayi woti anthu omwe ali ndi neutropenia yoopsa azidwala khansa ya m'magazi. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa.

Filgrastim zopangira jekeseni zingayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamagwiritsa ntchito mankhwalawa.

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani mankhwala a filgrastim mu firiji. Ngati mwangozi amaunditsa filgrastim (Neupogen, Nivestym, Zarxio), mutha kuyilola kuti isungunuke mufiriji. Komabe, ngati muumitsa syringe kapena botolo la filgrastim kachiwiri, muyenera kutaya syringe kapena botolo. Filgrastim (Neupogen, Nivestym, Zarxio) imatha kusungidwa kutentha mpaka maola 24 koma iyenera kusungidwa ndi dzuwa. Filgrastim (Granix) ikhoza kusungidwa mufiriji kwa maola 24, kapena itha kusungidwa kutentha mpaka masiku 5 koma iyenera kutetezedwa ku kuwala.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti aone momwe thupi lanu lingayankhire pazinthu zopangira jekeseni wa filgrastim.

Musanaphunzire za kulingalira za fupa, uzani dokotala ndi waluso kuti mukugwiritsa ntchito jekeseni wa filgrastim. Zida zopangira jekeseni ya Filgrastim zimatha kukhudza zotsatira za kafukufukuyu.

Musalole kuti wina aliyense agwiritse ntchito mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Granix^® (zolemba-filgrastim)
• Neupogen^® (zoyenda)
• Nivestym^® (zoyenda-aafi)
• Zarxio^® (zoyipa-sndz)

• Cholimbikitsa cha Granulocyte Colony
• G-CSF
• Wowonjezeranso Methionyl Wamunthu G-CSF