Angiokeratoma

Zamkati

• Kodi mitundu yosiyanasiyana ndi iti?
• Zizindikiro zake ndi ziti?
• Kodi chimayambitsa angiokeratoma ndi chiyani?
• Kodi angiokeratoma imapezeka bwanji?
• Amachizidwa bwanji?
• Kodi malingaliro a anthu omwe ali ndi angiokeratoma ndi otani?

Kodi angiokeratoma ndi chiyani?

Angiokeratoma ndi mkhalidwe womwe mawanga ang'onoang'ono amdima amawoneka pakhungu. Amatha kuwonekera kulikonse m'thupi lanu. Zilondazi zimachitika pamene timitsempha tating'onoting'ono ta magazi totchedwa capillaries timatanuka, kapena kufutukuka, pafupi ndi khungu lanu.

Ma Angiokeratomas amatha kumva kukwiya mpaka kukhudza. Nthawi zambiri amawoneka pagulu pakhungu mozungulira:

• mbolo
• scrotum
• maliseche
• labia majora

Amatha kulakwitsa chifukwa cha totupa, khansa yapakhungu, kapena matenda ngati maliseche kapena herpes. Nthawi zambiri, ma angiokeratomas alibe vuto lililonse ndipo safunika kuthandizidwa.

Angiokeratomas nthawi zina amatha kukhala chizindikiro cha vuto, monga matenda osowa amtundu wotchedwa Fabry matenda (FD). Muyenera kukaonana ndi dokotala kuti akuthandizeni kupewa zovuta.

Kodi mitundu yosiyanasiyana ndi iti?

Mitundu ya angiokeratoma ndi monga:

• Angiokeratoma yokhayokha. Izi nthawi zambiri zimawoneka zokha. Nthawi zambiri amapezeka m'manja ndi m'miyendo yanu. Sizowononga.
• Angiokeratoma wa Fordyce. Izi zimawoneka pakhungu la chikopa kapena kumaliseche. Amapezeka kwambiri pachikwama m'magulu akuluakulu. Mtundu uwu umatha kukhala pathupi pa amayi apakati. Sali ovulaza, koma amakonda kutuluka magazi ngati akanda.
• Angiokeratoma wa Mibelli. Izi zimachokera ku mitsempha yambiri yamagazi yomwe ili pafupi kwambiri ndi khungu, kapena khungu lanu. Sizowononga. Mtundu uwu umawumitsa ndikulimba pakapita nthawi mu njira yotchedwa hyperkeratosis.
• Angiokeratoma circumscriptum. Uwu ndi mawonekedwe osowa kwambiri omwe amapezeka m'magulu amiyendo yanu kapena torso. Mutha kubadwa ndi mtundu uwu. Zimakhala zosawoneka bwino pakapita nthawi, zimakhala zakuda kapena mawonekedwe osiyanasiyana.
• Angiokeratoma corporis diffusum. Mtundu uwu ndi chizindikiro cha FD. Zitha kuchitika ndimatenda ena am'maso, omwe amakhudza momwe maselo amagwirira ntchito. Izi ndizosowa ndipo zimakhala ndi zizindikilo zina, monga kutentha kwa manja ndi mapazi kapena mavuto amaso. Ma angiokeratomas awa amapezeka kwambiri kuzungulira thupi. Amatha kuwonekera paliponse kuyambira pansi pamimba mpaka ntchafu zanu.

Zizindikiro zake ndi ziti?

Mawonekedwe enieni, kukula kwake, ndi utoto wake zimasiyana. Muthanso kukhala ndi zisonyezo zina ngati muli ndi vuto logwirizana, monga FD.

Mwambiri, ma angiokeratomas amawonetsa izi:

• imawoneka ngati mabampu ang'onoang'ono mpaka apakatikati kuyambira 1 millimeter (mm) mpaka 5 mm kapena munthawi zosanjikizana, zofananira
• ali ndi mawonekedwe ofanana ndi dome
• kumva wandiweyani kapena wolimba kumtunda
• onetsani nokha kapena m'magulu ochepa chabe mpaka pafupifupi zana
• ndi akuda, kuphatikiza ofiira, amtambo, ofiyira kapena akuda

Ma Angiokeratomas omwe awoneka kumene amakhala ofiira. Mawanga omwe akhala pakhungu lanu kwakanthawi nthawi zambiri amakhala akuda.

Ma Angiokeratomas pamatendawa amathanso kuwonekera limodzi ndi kufiira kudera lalikulu la scrotum. Angiokeratomas pamatumbo kapena kumaliseche amathanso kutuluka magazi mosavuta akamakandidwa kuposa ziwalo zina za thupi lanu.

Ngati muli ndi vuto ngati FD lomwe limapangitsa kuti angiokeratomas awonekere, zizindikilo zina zomwe mungakumane nazo ndi monga:

• acroparesthesias, kapena kupweteka m'manja ndi m'mapazi
• tinnitus, kapena phokoso lolira m'makutu anu
• kuwoneka bwino, kapena mitambo m'masomphenya anu
• hypohidrosis, kapena kusakhoza thukuta moyenera
• kupweteka m'mimba mwako ndi matumbo
• kumva chofuna kukachita chimbudzi mukatha kudya

Kodi chimayambitsa angiokeratoma ndi chiyani?

Angiokeratomas amayamba chifukwa cha kuchepa kwa mitsempha yamagazi pafupi ndi khungu. Angiokeratomas payekha mwina amayamba chifukwa chovulala komwe kudachitika m'deralo momwe amawonekera.

FD imafalikira m'mabanja, ndipo imatha kuyambitsa angiokeratomas. Pafupifupi 1 mwa amuna 40,000 mpaka 60,000 aliwonse ali ndi FD, malinga ndi dipatimenti ya U.S. National Library of Medicine ya genetics.

Zina kupatula kuyanjana kwawo ndi FD komanso zina zam'magazi, sizimadziwika nthawi zonse chomwe chimayambitsa angiokeratomas. Zomwe zingayambitse ndi izi:

• matenda oopsa, kapena kuthamanga kwa magazi m'mitsempha pafupi ndi khungu
• kukhala ndi vuto lomwe limakhudza mitsempha yamagazi yakomweko, monga inguinal hernia, zotupa m'mimba, kapena varicocele (pamene mitsempha mu scrotum ikukulira)

Kodi angiokeratoma imapezeka bwanji?

Angiokeratomas nthawi zambiri amakhala opanda vuto. Sikuti nthawi zonse mumayenera kukaonana ndi dokotala kuti akuthandizeni.

Koma mukawona zizindikiro zina, monga kutuluka magazi pafupipafupi kapena zizindikiro za FD, pitani kuchipatala nthawi yomweyo kuti akuthandizeni. Mwinanso mungafune kuwona dokotala ngati mukuganiza kuti malo omwe amawoneka ngati angiokeratoma atha kukhala a khansa.

Dokotala wanu atenga zitsanzo za angiokeratoma kuti azindikire. Izi zimadziwika kuti biopsy. Munthawi imeneyi, adotolo angachotse, kapena kudula, angiokeratoma pakhungu lanu kuti muchotse. Izi zitha kuphatikizira dokotala wanu pogwiritsa ntchito scalpel kuti achotse angiokeratoma pansi pake pakhungu.

Dokotala wanu angalimbikitsenso kuyesa kwa majini a GLA kuti muwone ngati muli ndi FD. FD imayambitsidwa ndi kusintha kwa jini ili.

Amachizidwa bwanji?

Angiokeratomas nthawi zambiri safunika kuthandizidwa ngati simukumana ndi vuto lililonse kapena kupweteka. Mungafune kuti achotsedwe ngati amatuluka magazi pafupipafupi kapena pazodzikongoletsa. Poterepa, pali njira zingapo zamankhwala:

• Electrodessication ndi curettage (ED & C). Dokotala wanu amapha malo ozungulira angiokeratomas ndi anesthesia yakomweko, kenako amagwiritsa ntchito zida zamagetsi zamagetsi ndi zida zochotsera mawanga ndikuchotsa minofu.
• Kuchotsa laser. Dokotala wanu amagwiritsa ntchito lasers, monga pulsed dye laser, kuti awononge mitsempha yambiri yamagazi yomwe imayambitsa angiokeratomas.
• Cryotherapy. Dokotala wanu amaunditsa ma angiokeratomas ndi ziphuphu zozungulira ndikuzichotsa.

Chithandizo cha FD chingaphatikizepo mankhwala, monga:

• Agalsidase beta (Fabrazyme). Mudzalandira jakisoni wokhazikika wa Fabrazyme kuti muthandizire thupi lanu kuphwanya mafuta owonjezera omwe amangidwa chifukwa chosowa enzyme yoyambitsidwa ndi kusintha kwa majini a GLA.
• Neurontin (Gabapentin) kapena carbamazepine (Tegretol). Mankhwalawa amatha kupweteka kwamanja ndi phazi.

Dokotala wanu angakulimbikitseninso kuti muwone akatswiri azizindikiro za FD zamtima, impso, kapena zamanjenje.

Kodi malingaliro a anthu omwe ali ndi angiokeratoma ndi otani?

Angiokeratomas nthawi zambiri samakhala ndi nkhawa. Onani dokotala wanu ngati muwona kutuluka kwa magazi kapena kuvulala kuma angiokeratomas, kapena ngati mukuganiza kuti pali vuto lomwe limakupangitsani kusapeza bwino kapena kupweteka.