Kodi B-Cell Lymphoma Ndi Chiyani?
Zamkati
- Kodi B-cell lymphoma ndi chiyani?
- Kusinthana
- Zizindikiro zake ndi ziti?
- Amachizidwa bwanji?
- Mafunde
- Chemotherapy
- Chithandizo chamankhwala
- Kupanga khungu la tsinde
- Kodi pali zovuta zina?
- Kodi kuchira kuli bwanji?
- Chiwonetsero
Chidule
Lymphoma ndi mtundu wa khansa yomwe imayamba mu ma lymphocyte. Ma lymphocyte ndimaselo amthupi. Hodgkin's ndi non-Hodgkin's lymphoma ndi mitundu iwiri yayikulu ya lymphoma.
T-cell lymphoma ndi B-cell lymphoma ndi mitundu iwiri ya non-Hodgkin's lymphoma. Palinso mtundu wosowa wotchedwa NK-cell lymphoma.
Mwa anthu omwe alibe Hodgkin lymphoma, pafupifupi 85% ali ndi B-cell lymphoma.
Chithandizo cha B-cell lymphomas chimachokera pamtundu winawake wa matenda.
Kodi B-cell lymphoma ndi chiyani?
Pali mitundu ingapo ya B-cell lymphoma, yomwe ikukula pang'onopang'ono (indolent) ndikukula mwachangu (mwamakani), kuphatikiza:
| B-cell subtype | Makhalidwe |
| Imafalitsa lalikulu B-cell lymphoma (DLBCL) | Uwu ndiye mtundu wofala kwambiri wa non-Hodgkin's lymphoma. Ndi khansa yaukali koma yochiritsidwa yomwe imatha kukhala ndi ma lymph node ndi ziwalo zina. |
| Follicular lymphoma | Uwu ndiye mtundu wachiwiri wofala kwambiri pa non-Hodgkin's lymphoma. Imakula pang'onopang'ono ndipo nthawi zambiri imayamba m'mimba. |
| Mantel cell lymphoma | Nthawi zambiri zimakhudzanso ma lymph node, mafupa, ndulu, komanso m'mimba. |
| Matenda a lymphocytic khansa (CLL) / Small lymphocytic lymphoma (SLL) | Mtundu uwu ndiwololera ndipo umakhudza mwazi ndi mafupa (CLL), kapena ma lymph node ndi spleen (SLL). |
| Njira yayikulu yapakati yamanjenje lymphoma | Mtundu uwu nthawi zambiri umayambira muubongo kapena msana. Zimakhudzana ndi mavuto amthupi omwe amabwera chifukwa cha Edzi kapena mankhwala oletsa kukana omwe amagwiritsidwa ntchito kutsatira kumuika thupi. |
| Malo ozungulira ozungulira B-cell lymphoma | Uwu ndi mtundu wokula pang'onopang'ono womwe umayamba mumphamba ndi m'mafupa. |
| Malo owonjezera ozungulira B-cell lymphoma a MALT | Mtundu uwu nthawi zambiri umakhudza m'mimba. Zitha kupezekanso m'mapapu, khungu, chithokomiro, malovu am'maso, kapena diso. |
| Malo ozungulira m'mphepete mwa B-cell lymphoma | Uwu ndi mtundu wosowa, wofulumira kukula womwe umapezeka makamaka mu ma lymph node. |
| Burkitt lymphoma | Umenewu ndi mtundu womwe ukukula mwachangu womwe umafala kwambiri mwa ana. |
| Khansa ya m'magazi | Uwu ndi mtundu wokula pang'onopang'ono womwe umakhudza ndulu, ma lymph node, ndi magazi. |
| Lymphoplasmacytic lymphoma (Waldenstrom macroglobulinemia) | Ichi ndi kachilombo kamene kamapezeka pang'onopang'ono, kamphindi, ndi ma lymph nodes. |
| Primary effusion lymphoma | Ichi ndi mtundu wosowa, wankhanza womwe umakonda kupezeka mwa anthu omwe ali ndi chitetezo chamthupi chofooka. |
Kusinthana
Khansa yachitika malinga ndi momwe yafalikira kuchokera pamalo oyamba. Non-Hodgkin's lymphoma imayikidwa kuyambira 1 mpaka 4, ndipo 4 ndiyo yopambana kwambiri.
Zizindikiro zake ndi ziti?
Zizindikiro zimasiyanasiyana kutengera mtundu wa B-cell lymphoma komanso kutukuka kwake. Izi ndi zina mwazizindikiro zazikulu:
- zotupa zam'mimba m'khosi mwanu, m'khwapa, kapena kubuula
- kupweteka m'mimba kapena kutupa
- kupweteka pachifuwa
- kukhosomola
- kupuma movutikira
- malungo ndi thukuta usiku
- kuonda
- kutopa
Amachizidwa bwanji?
Mitundu ina ya lymphoma yomwe imakhala yopanda mphamvu komanso yopanda chilema sikutanthauza chithandizo. Dokotala wanu angakupatseni malangizo othandiza kuti muzidikira. Izi zikutanthauza kuti muzitsatira miyezi ingapo iliyonse kuti muwonetsetse kuti khansayo sakupita patsogolo. Nthawi zina, izi zimatha kupitilira zaka.
Chithandizo chitha kuyamba pomwe zizindikiro zikuwonekera kapena ngati pali zizindikiro zakukula kwa matenda. B-cell lymphoma nthawi zambiri imaphatikizapo kuphatikiza mankhwala, omwe amatha kusintha pakapita nthawi.
Mafunde
Pogwiritsira ntchito mphamvu zamagetsi zamagetsi, mankhwala a radiation amagwiritsidwa ntchito kupha ma cell a khansa ndikuchepetsa zotupa. Zimafunikira kugona patebulo pomwe matabwawo alunjika pomwepo pathupi panu.
Kuti mukhale ndi lymphoma yomwe ikukula pang'onopang'ono, chithandizo cha radiation chingakhale zonse zomwe mukufuna.
Zotsatira zoyipazi zimatha kukhala kutopa komanso kukwiya pakhungu.
Chemotherapy
Chemotherapy ndi mankhwala amachitidwe omwe amatha kuperekedwa pakamwa kapena kudzera m'mitsempha. Ma B-cell lymphomas ena owopsa amatha kuchiritsidwa ndi chemotherapy, makamaka kumayambiriro kwa matenda.
DLBCL ndi mtundu wokula msanga womwe ungathe kuchiritsidwa ndi chemotherapy regimen yotchedwa CHOP (cyclophosphamide, doxorubicin, vincristine, ndi prednisone). Mukaperekedwa limodzi ndi monoclonal antibody rituximab (Rituxan), amatchedwa R-CHOP. Nthawi zambiri amaperekedwa mozungulira milungu ingapo. Ndizovuta pamtima, motero sizosankha ngati muli ndi mavuto amtima omwe analipo kale.
Zotsatira zoyipa za chemotherapy zimatha kuphatikizira kunyoza, kutopa, komanso tsitsi.
Chithandizo chamankhwala
Mankhwala osokoneza bongo amathandiza chitetezo chanu cha mthupi kuthana ndi khansa. Rituximab imalimbitsa mapuloteni omwe ali pamwamba pa ma B-cell, zomwe zimapangitsa kuti chitetezo chamthupi chitetezeke kuzizindikira ndikuziwononga. Pochepetsa ma cell a B omwe ali ndi khansa komanso athanzi, mankhwalawa amalimbikitsa thupi lanu kuti lipange ma B-cell abwino. Izi zimapangitsa kuti khansa isadzayambirenso.
Mankhwala a radioimmunotherapy, monga ibritumomab tiuxetan (Zevalin), amapangidwa ndi ma anti-monoclonal antibodies omwe amanyamula ma isotopi a radioactive. Mankhwalawa amathandiza ma antibodies omwe amadziphatika m'maselo a khansa kuti apereke radiation.
Zotsatira zoyipa zamankhwala amthupi zimatha kuphatikizira kuchuluka kwama cell oyera, kutopa, ndi matenda.
Kupanga khungu la tsinde
Kusintha kwa khungu la tsinde kumaphatikizapo kusintha mafuta m'mafupa anu kuchokera kwa wopereka wathanzi. Choyamba, mudzafunika chemotherapy kapena radiation kuti muchepetse chitetezo chanu chamthupi, kuwononga ma cell a khansa, ndikupangira malo am'mafupa atsopano. Kuti mukhale woyenera, muyenera kukhala athanzi lokwanira kupirira mankhwalawa.
Zotsatira zoyipazi zimatha kuphatikizira matenda, kuchepa magazi m'thupi, ndikukana m'mafupa atsopano.
Kodi pali zovuta zina?
Lymphomas imafooketsa chitetezo chanu chamthupi, ndikupangitsa kuti mukhale osatetezeka kumatenda. Mankhwala ena a lymphoma angayambitse mavuto monga:
- osabereka
- mtima, mapapo, impso, ndi matenda a chithokomiro
- matenda ashuga
- khansa yachiwiri
B-cell lymphomas imatha kukula ndikufalikira kumadera akutali.
Kodi kuchira kuli bwanji?
Mitundu ina ya ma B-cell lymphomas imatha kuchiritsidwa. Chithandizo chimatha kuchepetsa kukula kwa ena. Ngati palibe chizindikiro cha khansa mutalandira chithandizo chamankhwala choyambirira, ndiye kuti mukukhululukidwa. Mufunikirabe kutsatira kwa zaka zingapo kuti muwone ngati zingabwererenso.
Chiwonetsero
Kuchuluka kwa zaka zisanu zapakati pa non-Hodgkin's lymphoma ndi 70 peresenti. Izi zimasiyanasiyana kwambiri kutengera mtundu wa B-cell lymphoma ndi gawo lodziwika. Zina zomwe mungaganizire ndi msinkhu wanu komanso thanzi lanu lonse.
Mwachitsanzo, DLBCL imachiritsidwa pafupifupi theka la anthu omwe ali nayo. Omwe amayamba kulandira chithandizo m'mbuyomu amakhala ndi malingaliro abwino kuposa omwe ali ndi matenda amtsogolo.
Dokotala wanu amatha kukupatsirani malingaliro anu kutengera mawonekedwe anu azaumoyo.
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