Chilichonse Chimene Muyenera Kudziwa Ponena za Cholestasis

Zamkati

• Zizindikiro
• Zimayambitsa cholestasis
• Mankhwala
• Matenda
• Cholestasis wa mimba
• Zomwe zimayambitsa komanso zoopsa
• Matendawa
• Chithandizo
• Chiwonetsero

Kodi cholestasis ndi chiyani?

Cholestasis ndi matenda a chiwindi. Zimachitika pamene kutuluka kwa ndulu kuchokera pachiwindi kumachepa kapena kutsekedwa. Bile ndimadzimadzi omwe amapangidwa ndi chiwindi chanu chomwe chimathandizira kupukusa chakudya, makamaka mafuta. Kutuluka kwa bile kusinthidwa, kumatha kubweretsa kuchuluka kwa bilirubin. Bilirubin ndi pigment yopangidwa ndi chiwindi chanu ndipo imatuluka mthupi lanu kudzera mu bile.

Pali mitundu iwiri ya cholestasis: intrahepatic cholestasis ndi extrahepatic cholestasis. Intrahepatic cholestasis imayambira mkati mwa chiwindi. Itha kuyambitsidwa ndi:

• matenda
• matenda
• kugwiritsa ntchito mankhwala osokoneza bongo
• zovuta zamtundu
• zotsatira za mahomoni pa kutuluka kwa bile

Mimba imathandizanso kuti mukhale ndi chiopsezo chotere.

Extrahepatic cholestasis imayambitsidwa ndi cholepheretsa kuthupi. Kutseka kwa zinthu monga ma ndulu, zotupa, ndi zotupa kumalepheretsa kutuluka kwa ndulu.

Werengani kuti mudziwe zambiri za vutoli.

Zizindikiro

Mitundu yonse iwiri ya cholestasis imabweretsa zizindikilo zofananira:

• jaundice, komwe kumakhala chikasu pakhungu lako komanso maso oyera
• mkodzo wakuda
• chopondapo chowala
• kupweteka m'mimba mwako
• kutopa
• nseru
• kuyabwa kwambiri

Sikuti aliyense amene ali ndi cholestasis ali ndi zizindikilo, ndipo akulu omwe ali ndi cholestasis omwe alibe matenda.

Zimayambitsa cholestasis

Kutsekeka kwa ma bile kumatha kuyambitsidwa ndi zinthu zingapo.

Mankhwala

Chiwindi chanu chimagwira gawo lofunikira pakupukusa mankhwala. Mankhwala ena ndi ovuta kwambiri kuti chiwindi chanu chizitha kupukusa mafuta poizoni. Mankhwalawa ndi awa:

• maantibayotiki ena, monga amoxicillin (Amoxil, Moxatag) ndi minocycline (Minocin)
• anabolic mankhwala
• anti-steroidal anti-inflammatories (NSAIDs), monga ibuprofen (Advil, Motrin IB)
• njira zakulera zam'kamwa
• mankhwala ena oteteza khunyu
• mankhwala ena oletsa mafangayi
• mankhwala ena opatsirana pogonana
• mankhwala ena opha tizilombo

Nthawi zonse muyenera kumwa mankhwala monga mwauzidwa, ndipo osasiya kumwa mankhwala omwe dokotala wakupatsani popanda kulankhula nawo kaye.

Matenda

Matenda ena amamuyambitsa timabala kapena kutupa pamatope a bile, omwe amatsogolera ku cholestasis. Zinthu monga:

• matenda opatsirana ndi ma virus monga HIV, hepatitis, cytomegalovirus, ndi Epstein-Barr
• matenda a bakiteriya
• Matenda ena amadzimadzi, monga primary biliary cirrhosis, omwe amatha kuyambitsa chitetezo chamthupi chanu kuti chiwonongeke
• Matenda amtundu, monga matenda amzere
• Khansa ina, monga khansa ya chiwindi komanso kapamba, komanso ma lymphomas

Cholestasis wa mimba

Intrahepatic cholestasis ya mimba, yomwe imadziwikanso kuti obstetric cholestasis, akuti imachitika pakati pa 1 mpaka 2 pa azimayi 1,000 aliwonse ku United States. Chizindikiro chofala kwambiri cha obstetric cholestasis ndikumayabwa popanda zotupa. Izi zimachitika chifukwa cha kuchuluka kwa bile acid m'magazi.

Kuyabwa kumachitika miyezi itatu yapitayi ya mimba. Ikhozanso kutsagana ndi:

• jaundice
• mipando yotumbululuka
• mkodzo wakuda
• kupweteka m'mimba
• nseru

Onani dokotala wanu ngati mukuyabwa mukakhala ndi pakati. Mankhwala ena ogulitsa, monga antihistamines kapena anti-itch creams okhala ndi cortisone, nthawi zambiri sagwira ntchito pochiza vutoli ndipo atha kuvulaza mwana wanu wosabadwa. M'malo mwake, dokotala wanu akhoza kukupatsani mankhwala omwe amathandiza ndi kuyabwa koma osavulaza mwana wanu.

Zomwe zimayambitsa komanso zoopsa

Cholestasis yomwe imachitika panthawi yapakati imatha kukhala cholowa chobadwa nacho. Ngati amayi kapena mlongo wanu anali ndi vutoli panthawi yapakati, mutha kukhala ndi chiopsezo chowonjezeranso kukulira cholestasis.

Mahomoni oyembekezera amathanso kubweretsa vutoli. Izi ndichifukwa choti zimatha kukhudza kugwira ntchito kwanu kwa ndulu, kulola kuti ndulu ikule ndikutuluka m'magazi anu.

Amayi omwe amakhala ndi zochulukitsa ali pachiwopsezo chachikulu chotenga cholestasis yobereka.

Matendawa

Dokotala wanu adzafunsa mafunso okhudza mbiri yanu yazachipatala. Muyeneranso kuyezetsa thupi. Mayeso amwazi atha kulamulidwa kuti ayese michere ya chiwindi yomwe ikuwonetsa cholestasis. Ngati zotsatira zoyeserera sizachilendo, dokotala wanu atha kuyitanitsa mayeso oyerekeza ngati ultrasound kapena MRI. Dokotala wanu amathanso kupanga chiwindi cha chiwindi.

Chithandizo

Njira yoyamba yothira cholestasis ndikuwunika chomwe chimayambitsa. Mwachitsanzo, ngati atsimikiza kuti mankhwala akuyambitsa vutoli, dokotala wanu angakulimbikitseni mankhwala ena. Ngati chotchinga ngati ma gallstones kapena chotupa chikuyambitsa kusungidwa kwa bile, dokotala wanu angakulimbikitseni kuchitidwa opaleshoni.

Nthawi zambiri, obstetric cholestasis imatha pambuyo pobereka. Azimayi omwe amakhala ndi cholestasis wobereka ayenera kuyang'aniridwa pambuyo pathupi.

Chiwonetsero

Cholestasis imatha kuchitika msinkhu uliwonse, komanso mwa amuna ndi akazi. Kubwezeretsa kumatengera kukula kwa milanduyo isanapezeke koyamba. Chifukwa china ndichomwe chimayambitsa matendawa komanso momwe angathetsere matendawa. Mwachitsanzo, miyala yamtengo wapatali imatha kuchotsedwa, yomwe imachiritsa matendawa. Ngati vutoli limayamba chifukwa cha kuwonongeka kwa chiwindi, kuchira kumakhala kovuta kwambiri.

Mutha kuchita zinthu zingapo kuti muchepetse chiopsezo cha cholestasis:

• Pezani katemera wa matenda a chiwindi.
• Osamwa mowa mopitirira muyeso.
• Pewani kugwiritsa ntchito mankhwala osokoneza bongo.

Onani dokotala wanu nthawi yomweyo ngati mukuganiza kuti muli ndi cholestasis. Chithandizo choyambirira chitha kukupatsani mwayi wochira.