Izi ndi Zomwe Muyenera Kudziwa Zokhudza Zotsatira Za Katemera wa COVID Ngati Muli ndi Zodzoladzola Zodzikongoletsera

Zamkati

• Choyamba, kodi mbali iyi ndi yochuluka motani kuchokera ku katemera?
• Chifukwa chiyani munthu yemwe ali ndi zodzaza amatha kutupa atalandira katemera wa COVID-19?
• Zomwe Muyenera Kuchita Ngati Mudakhala Ndi Zodzaza Ndi Kukonzekera Kupeza Katemera wa COVID-19
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Chaka chatsala pang'ono kuti, Food and Drug Administration idanenanso za katemera watsopano komanso wosayembekezereka wa katemera wa COVID-19: kutupa kwa nkhope.

Anthu awiri - wazaka 46 komanso wazaka 51 - omwe adalandira katemera wa Moderna COVID-19 pamayesero azachipatala adakumana ndi "zolumikizana kwakanthawi" (kutanthauza kumbali ya nkhope) kutupa mkati mwa masiku awiri atalandira. Mlingo wawo wachiwiri wakuwombera, malinga ndi lipotilo. Kodi akuganiziridwa chifukwa cha kutupa? Cosmetic filler. "Mitu yonseyi inali ndi dermal filler," FDA idatero mu lipotilo. Bungweli silinafotokozenso zambiri, ndipo wolemba nkhani ku Moderna sanabwerere MaonekedwePempho la ndemanga lisanatulutsidwe.

Ngati muli ndi zodzikongoletsera kapena mwakhala mukuziganizira, mwina muli ndi mafunso ena pazomwe mungayembekezere ngati mutalandira katemera wa COVID-19 - kaya Moderna, Pfizer, kapena makampani ena aliwonse omwe posachedwa angalandire chilolezo chogwiritsa ntchito mwadzidzidzi kuchokera FDA. Nazi zomwe muyenera kudziwa.

Choyamba, kodi mbali iyi ndi yochuluka motani kuchokera ku katemera?

Osati kwambiri. Kutupa kumaso sikunaphatikizidwe pamndandanda wazotsatira zodziwika bwino za katemera wa COVID-19 kuchokera ku Centers for Disease Control and Prevention. Ndipo a FDA adalemba malipoti awiri okha okhudzana ndi izi mwa anthu opitilira 30,000 omwe adachita nawo mayeso azachipatala a Moderna (mpaka pano, zotsatira zake sizinafotokozedwe ndi katemera wa Pfizer kapena katemera wa kampani ina iliyonse ya COVID-19).

Kuti anati, STAT, malo azachipatala omwe adalemba maulamuliro a FDA za izi mu Disembala, adanenanso munthu wachitatu pamlandu wa Moderna yemwe adati adapanga milomo angioedema (kutupa) patatha masiku awiri atalandira katemera (sizikudziwika ngati izi zidachitika munthu woyamba kapena mlingo wachiwiri). "Munthuyu anali atalandirapo kale jakisoni pakamwa," atero a Rachel Zhang, MD, wogwira ntchito zachipatala ku FDA, STAT. Dr. Zhang sanatchule nthawi yomwe munthuyu anali atapeza kale njira zawo zodzazira. (Zogwirizana: Chilichonse Chimene Muyenera Kudziwa Zokhudza Katemera wa COVID-19)

Pomwe a FDA sananene kuti ndi anthu angati m'mayesero a Moderna omwe anali ndi zodzikongoletsera, pafupifupi anthu 3 miliyoni ku US amadzaza chaka chilichonse, malinga ndi American Society of Plastic Surgeons - ndiye njira yodziwika bwino. Koma ndi zochitika zitatu zokha zotupa kumaso pamayesero omwe adakhudza anthu opitilira 30,000, zikutanthauza kuti pali mwayi m'modzi mwa 10,000 wokhala ndi kutupa kumaso atalandira katemera wa COVID-19. M’mawu ena: N’zosatheka.

Chifukwa chiyani munthu yemwe ali ndi zodzaza amatha kutupa atalandira katemera wa COVID-19?

Chifukwa chenichenicho sichikudziwika pakadali pano, koma kutupa ndi "mwina chinthu chogwirana pakati pa katemerayu ndi zinthu zomwe zimadzazidwa," akutero katswiri wodziwa za matenda opatsirana Amesh A. Adalja, MD, katswiri wamkulu ku Johns Hopkins Center for Chitetezo Chaumoyo.

Katemera wa Moderna amaphatikizapo mRNA (molekyulu yomwe imaphunzitsa thupi lanu kuti ipange mtundu wake wa protein ya COVID-19 ngati njira yokonzekeretsa thupi lanu kudziteteza ku kachilomboka), mitundu ingapo ya lipids (mafuta omwe kuthandizira kunyamula mRNA kupita ku maselo oyenera), tromethamine ndi tromethamine hydrochloride (ma alkalizer omwe amagwiritsidwa ntchito kwambiri pakatemera kuti agwirizane ndi pH mlingo wa katemera ndi wa matupi athu), acetic acid (asidi wachilengedwe omwe amapezeka mu viniga yemwenso amathandiza kuti pH ikhale yotetezeka pH), sodium acetate (mtundu wa mchere womwe umagwiritsanso ntchito pH kukhazikika kwa katemera komanso umagwiritsidwanso ntchito mu IV madzimadzi), ndi sucrose (aka shuga - chinthu china chokhazikika chokhazikika cha katemera) .

Ngakhale kuti lipids imodzi ya katemera, polyethylene glycol, yakhala ikugwirizana ndi zotsatira za ziwengo m'mbuyomu, Dr. Adalja akuti n'zovuta kudziwa ngati chosakaniza ichi - kapena china chilichonse, pankhaniyi - chikukhudzidwa makamaka ndi kutupa kwa anthu omwe ali ndi zodzaza.

Lipoti la FDA silinafotokoze mwatsatanetsatane mtundu wa zodzikongoletsera zomwe odwalawa adalandira. American Academy of Dermatology imanena kuti zosakaniza zodziwika bwino, makamaka, zimaphatikizapo mafuta omwe amatengedwa m'thupi lanu, hyaluronic acid (shuga wopezeka mwachilengedwe m'thupi lomwe limapangitsa khungu kukhala lakuda, kuphulika, ndi kuwala), calcium hydroxylapatite (makamaka. calcium yokhala ndi jakisoni yomwe imathandizira kupangitsa khungu kupanga khungu la collagen), poly-L-lactic acid (asidi yomwe imalimbikitsanso mapangidwe a collagen), ndi polymethylmethacrylate (collagen booster ina). Iliyonse mwa zodzaza izi zitha kubwera ndi zotsatira zake zapadera komanso mawonekedwe ake. Koma popeza a FDA sanatchule mtundu wanji wa mitundu (kapena mitundu) yazodzaza yomwe anthuwa anali nayo, "sizikudziwika bwino momwe zingakhalire," akutero Dr. Adalja. "Pali mafunso ambiri omwe akuyenera kuyankhidwa." (Zogwirizana: Buku Lathunthu la Ma Jekeseni Odzaza)

Chosangalatsa ndichakuti munthu yemwe akuti adatupa milomo atalandira katemera wa Moderna COVID-19 adati "adachitanso chimodzimodzi pambuyo pa katemera wa chimfine wam'mbuyomu," adatero Dr. Zhang pofotokoza za FDA za katemera wa Moderna, malinga ndi STAT.

Kufotokozera kumodzi pazotsatirazi - kaya katemera wa Moderna wa COVID-19, katemera wa chimfine, kapena katemera wina aliyense - ndikuti "cholinga cha chitetezo chamthupi ndi katemera kungayambitsenso kutupa kumalo ena m'thupi, " akutero Jason Rizzo, MD, Ph.D., director of Mohs Surgery ku Western New York Dermatology. "Popeza dermal filler kwenikweni ndi chinthu chachilendo m'thupi, ndizomveka kuti maderawa amatha kukhala owopsa komanso otupa pamtunduwu," akufotokoza motero. (FYI: Kudzaza kwamadzimadzi sikofanana ndi Botox.)

Zomwe Muyenera Kuchita Ngati Mudakhala Ndi Zodzaza Ndi Kukonzekera Kupeza Katemera wa COVID-19

Zambiri zikusonkhanitsidwa pazotsatira za katemera wa COVID-19 wonse, koma ndikofunikira kulabadira zomwe zanenedwapo pakadali pano - ngakhale zoyipa zomwe zakhala zikuwoneka ochepa. Poganizira izi, Dr. Adalja akuti ndibwino kuti mulankhule ndi dokotala wanu wamkulu ngati muli ndi zodzaza ndipo mukukonzekera kulandira katemera wa COVID-19.

Ngati mupita patsogolo, onetsetsani kuti mumakhala muofesi ya omwe amakupatsani chithandizo kwa mphindi 15 mpaka 30 mutalandira katemera. (Wopereka chithandizo ayenera kutsatira malangizo a CDC ndikulimbikitsanso izi, koma sizimakupweteketsani kubwereza.) "Mukayamba kutupa, amatha kulandira mankhwala a steroids kapena antihistamines, kapena kuphatikiza kwake," akutero Dr. Adalja. Ngati mutayamba kutupa kumaso (kapena zotsatira zina zosayembekezereka) mutalandira katemera ndikuchoka pamalo opangira katemera, Dr. Adalja akukulangizani kuti muyimbire dokotala mwamsanga kuti adziwe chithandizo choyenera.

Ndipo, mukawona kutupa kwa nkhope (kapena zina zilizonse zokhudzana ndi zovuta) pambuyo pa mlingo woyamba wa katemera wanu wa COVID-19, onetsetsani kuti mukulankhula ndi adotolo ngati kuli bwino kupeza mlingo wachiwiri, atero Rajeev Fernando , MD, katswiri wamatenda opatsirana akugwira ntchito muzipatala za COVID-19 mdziko lonselo. Komanso, ngati mukuda nkhawa ndi zomwe zingayambitse kutupa, Dr. Fernando akuwonetsa kuti mungalankhule ndi wotsutsa, yemwe amatha kuyesa mayeso kuti awone zomwe zingayambitse zotsatirazi.

Dr. Adalja akutsindika kuti nkhaniyi sayenera kukulepheretsani kulandira katemera, ngakhale mutakhala ndi kapena mukuganiza zopeza zodzaza posachedwapa. Koma, akuti, "mungafune kusamala pang'ono za zizindikiro zomwe mumakumana nazo mutalandira katemera, ngati zilipo, ndikuyang'anitsitsa madera omwe mudakhala nawo."

Kwachidziwikire, Dr.

"Titha kuchiza kutupa," akutero, koma sitingathe kuchiza bwino COVID-19.

Zomwe zili munkhaniyi ndizolondola monga nthawi yolemba. Pomwe zosintha za coronavirus COVID-19 zikupitilizabe kusintha, ndizotheka kuti zina ndi zina zomwe zanenedwa m'nkhaniyi zasintha kuyambira pomwe zidasindikizidwa koyamba. Tikukulimbikitsani kuti mumayang'anitsitsa pafupipafupi ndi zinthu monga CDC, WHO, ndi dipatimenti yazaumoyo yakwanuko kuti mumve zambiri zamtunduwu komanso malingaliro awo.

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