Matenda a Crohn's Rash: Kodi Akuwoneka Motani?

Zamkati

• Zizindikiro za khungu
• Zilonda za Perianal
• Zilonda zam'kamwa
• Matenda a Metastatic Crohn
• Erythema nodosum
• Pyoderma gangrenosum
• Matenda a Sweet's
• Zogwirizana
• Zomwe zimachitika ndi mankhwala
• Kuperewera kwa Vitamini
• Zithunzi
• Chifukwa chiyani izi zimachitika
• Mankhwala
• Nthawi yoti muwonane ndi dokotala
• Mfundo yofunika

Matenda a Crohn ndi mtundu wamatenda otupa (IBD). Anthu omwe ali ndi matenda a Crohn amakhala ndi zotupa m'matumbo awo, zomwe zimatha kubweretsa zizindikilo monga:

• kupweteka m'mimba
• kutsegula m'mimba
• kuonda

Akuti pafupifupi 40 peresenti ya anthu omwe ali ndi matenda a Crohn amakhala ndi zizindikilo zomwe sizimakhudza gawo logaya chakudya.

Dera lomwe zizindikilo zimachitika kunja kwa gawo logaya chakudya ndi khungu.

Chifukwa chomwe matenda a Crohn angakhudzire khungu sichidziwika bwino. Zitha kukhala chifukwa cha:

• zotsatira zachindunji za matendawa
• chitetezo mthupi
• zomwe zimachitika ndi mankhwala

Pitilizani kuwerenga kuti mudziwe zambiri za matenda a Crohn komanso khungu.

Zizindikiro za khungu

Anthu omwe ali ndi matenda a Crohn amatha kukhala ndi zotupa zosiyanasiyana zakhungu. Tiyeni tiwone zina mwazomwe zili pansipa.

Zilonda za Perianal

Zilonda za Perianal zili mozungulira anus. Atha kukhala:

• chofiira
• kutupa
• zopweteka nthawi zina

Zilonda za Perianal zimatha kutengera mawonekedwe osiyanasiyana, kuphatikiza:

• zilonda
• ziphuphu
• ming'alu, kapena kugawanika pakhungu
• fistula, kapena kulumikizana kwachilendo pakati pa ziwalo ziwiri za thupi
• zikopa

Zilonda zam'kamwa

Zilonda zimatha kupezeka pakamwa. Zilonda zam'kamwa zikawoneka, mutha kuwona zilonda zopweteka mkamwa mwanu, makamaka mkati mwa masaya kapena milomo.

Nthawi zina zizindikiro zina zimatha kupezeka, kuphatikizapo:

• mlomo wogawanika
• zigamba zofiira kapena zosweka pakona pakamwa, zomwe zimatchedwa angular cheilitis
• milomo yotupa kapena m'kamwa

Matenda a Metastatic Crohn

Matenda a Metastatic Crohn ndi osowa.

Masamba omwe akhudzidwa kwambiri ndi awa:

• nkhope
• maliseche
• malekezero

Zitha kupezekanso m'malo omwe pali zikopa ziwiri zikopa pamodzi.

Zilondazi zimakhala ngati zolembapo, ngakhale nthawi zina zimawoneka ngati zilonda. Zimakhala zofiira kapena zofiirira. Zilonda zamatenda amatha kuwonekera pawokha kapena m'magulu.

Erythema nodosum

Erythema nodosum imadziwika ndi ziphuphu zofiira kapena zovulaza zomwe zimachitika pansi pa khungu.

Amapezeka nthawi zambiri kumapeto kwanu, makamaka kutsogolo kwa shin kwanu. Malungo, kuzizira, kupweteka, ndi zowawa zitha kuchitika.

Erythema nodosum ndiwonekera kwambiri pakhungu la matenda a Crohn. Nthawi zambiri, koma osati nthawi zonse, zimagwirizana ndi kuwuka.

Pyoderma gangrenosum

Vutoli limayamba ndi khungu pakhungu lomwe pamapeto pake limayamba kukhala chilonda kapena chilonda chokhala ndi chikasu. Mutha kukhala ndi chotupa chimodzi cha pyoderma gangrenosum kapena zotupa zambiri. Malo ofala kwambiri ndi miyendo.

Monga erythema nodosum, pyoderma gangrenosum imatha kuchitika nthawi yophulika. Zilondazo zikachira, pakhoza kukhala zipsera zazikulu. Pafupifupi 35 peresenti ya anthu amatha kuyambiranso.

Matenda a Sweet's

Sweet's syndrome imaphatikizapo ma papuleti ofiira ofiira omwe nthawi zambiri amaphimba mutu wanu, torso, ndi mikono. Amatha kuchitika padera kapena kukula limodzi kuti apange chikwangwani.

Zizindikiro zina za sweet's syndrome ndi monga:

• malungo
• kutopa
• zopweteka
• zowawa

Zogwirizana

Zina mwazomwe zimakhudzana ndi matenda a Crohn komanso zimatha kuyambitsa khungu. Zitsanzo zina ndi izi:

• psoriasis
• vitiligo
• systemic lupus erythematosus (SLE)
• autoimmune amyloidosis

Zomwe zimachitika ndi mankhwala

Nthawi zina, zotupa pakhungu zimapezeka mwa anthu omwe amamwa mtundu wa mankhwala a biologic otchedwa anti-TNF mankhwala. Zilondazi zimawoneka ngati chikanga kapena psoriasis.

Kuperewera kwa Vitamini

Matenda a Crohn angayambitse kusowa kwa zakudya m'thupi, kuphatikizapo mavitamini. Zosiyanasiyana izi zimatha kuyambitsa khungu. Zitsanzo ndi izi:

• Kulephera kwa nthaka. Kulephera kwa nthaka kumayambitsa zigamba zofiira kapena zikwangwani zomwe zingakhale ndi pustules.
• Kuperewera kwachitsulo. Kuperewera kwachitsulo kumayambitsa zigamba zofiira, zosweka pamakona amlomo.
• Kulephera kwa Vitamini C. Kuperewera kwa Vitamini C kumayambitsa magazi pansi pakhungu, zomwe zimayambitsa mawanga onga akumenya.

Zithunzi

Zizindikiro zakhungu zomwe zimakhudzana ndi matenda a Crohn zitha kuwoneka zosiyana kwambiri, kutengera mtundu ndi malo.

Pitani pazithunzi izi kuti mupeze zitsanzo.

Chifukwa chiyani izi zimachitika

Sizikudziwika bwino momwe matenda a Crohn amayambitsira khungu. Ochita kafukufuku akupitilizabe kufufuza funsoli.

Izi ndi zomwe tikudziwa:

• Zilonda zina, monga zotupa za perianal ndi metastatic, zimawoneka kuti zimayambitsidwa mwachindunji ndi matenda a Crohn. Akapangidwanso ndikuwunika ndi microscope, zotupazo zimakhala ndimatenda ofanana am'mimba.
• Zilonda zina, monga erythema nodosum ndi pyoderma gangrenosum, amakhulupirira kuti zimagawana njira zamatenda ndi matenda a Crohn.
• Zinthu zina zomwe zimayambitsa matenda a khungu, monga psoriasis ndi SLE, zimalumikizidwa ndi matenda a Crohn.
• Zinthu zachiwiri zokhudzana ndi matenda a Crohn, monga kuperewera kwa zakudya m'thupi komanso mankhwala omwe amagwiritsidwa ntchito pochiza, amathanso kuyambitsa khungu.

Ndiye zingatheke bwanji kuti zonsezi zigwirizane? Monga zina zomwe zimachitika pokha pokha, matenda a Crohn amaphatikiza chitetezo chamthupi chomwe chimalimbana ndi maselo athanzi. Izi ndi zomwe zimabweretsa kutupa komwe kumakhudzana ndi vutoli.

Kafukufuku wa nyama wasonyeza kuti khungu loteteza thupi kumatenda lomwe limatchedwa khungu la Th17 ndilofunika mu matenda a Crohn. Maselo a Th17 amathandizidwanso ndi zovuta zina zokha, kuphatikiza zomwe zingakhudze khungu.

Mwakutero, maselowa atha kukhala olumikizana pakati pa matenda a Crohn's ndi zina mwazizindikiro zake pakhungu.

Kafukufuku wina akuwonetsa kuti pali zinthu zambiri zoteteza thupi zomwe zimakhudzana ndi matendawa.

Komabe, kufufuza kwina kuli kofunika kuti athetse mgwirizano pakati pa matenda a Crohn ndi khungu.

Mankhwala

Pali njira zosiyanasiyana zochiritsira zotupa pakhungu zomwe zimakhudzana ndi matenda a Crohn. Chithandizo chomwe mungalandire chimadalira mtundu wa zotupa pakhungu zomwe muli nazo.

Nthawi zina mankhwala amatha kuthandiza kuchepetsa khungu. Zitsanzo zina za mankhwala omwe wothandizira zaumoyo wanu angakupatseni ndi awa:

• corticosteroids, yomwe imatha kukhala yam'kamwa, jekeseni, kapena yapakhungu.
• mankhwala osokoneza bongo, monga methotrexate kapena azathioprine
• mankhwala oletsa kutupa, monga sulfasalazine
• anti-TNF biologics, monga infliximab kapena adalimumab
• maantibayotiki, omwe angathandize ndi fistula kapena abscesses

Mankhwala ena omwe angakhalepo ndi awa:

• kusiya anti-TNF biologic ngati ikuyambitsa khungu
• kuwonetsa kuti mavitamini akuthandizira pamene kuperewera kwa zakudya m'thupi kwadzetsa kusowa kwa vitamini
• kuchita opaleshoni kuchotsa fistula, kapena fistulotomy

Nthawi zina, zizindikiro za khungu zimatha kuchitika ngati gawo la matenda a Crohn's flare-up. Izi zikachitika, kuwongolera kuyambiranso kumathandizanso kuthana ndi khungu.

Nthawi yoti muwonane ndi dokotala

Ngati muli ndi matenda a Crohn ndikumakhala ndi zikopa zomwe mumakhulupirira kuti ndizokhudzana ndi matenda anu, kambiranani ndi omwe amakuthandizani azaumoyo.

Angafunikire kutenga biopsy kuti adziwe zomwe zimayambitsa matenda anu.

Nthawi zambiri, nthawi zonse pamakhala lamulo labwino kuti muwone omwe akukuthandizani mukawona zizindikiro zakhungu zomwe:

• kuphimba dera lalikulu
• kufalikira mofulumira
• Zimapweteka
• ali ndi matuza kapena ngalande yamadzi
• zimachitika ndi malungo

Mfundo yofunika

Anthu ambiri omwe ali ndi matenda a Crohn adzakumana ndi zizindikilo zomwe zimakhudza madera ena kupatula gawo logaya chakudya.

Limodzi mwa maderawa ndi khungu.

Pali mitundu yambiri ya zotupa pakhungu zomwe zimakhudzana ndi matenda a Crohn. Izi zitha kuchitika chifukwa cha:

• zotsatira zachindunji za matendawa
• zina chitetezo mthupi kugwirizana ndi matenda
• zovuta zokhudzana ndi matendawa, monga kuperewera kwa zakudya m'thupi

Chithandizo chimadalira mtundu wa zotupa. Nthawi zambiri zimaphatikizapo kumwa mankhwala kuti muchepetse matenda anu.

Ngati muli ndi matenda a Crohn ndikuwona zizindikiro za khungu zomwe mukuganiza kuti mwina ndizokhudzana, onani omwe akukuthandizani.