Matenda a Paget a m'mawere: ndi chiyani, zizindikiro ndi chithandizo

Zamkati

• Zizindikiro za matenda a Paget a m'mawere
• Momwe matendawa amapangidwira
• Kusiyanitsa matenda
• Chithandizo cha matenda a m'mawere a Paget

Matenda a Paget a m'mawere, kapena DPM, ndi mtundu wosowa wamatenda omwe nthawi zambiri amakhudzana ndi mitundu ina ya khansa ya m'mawere. Matendawa ndiwowonekera mwa azimayi asanakwanitse zaka 40, amapezeka kwambiri azaka zapakati pa 50 ndi 60. Ngakhale ndizosowa, matenda a Paget amabere amathanso kutuluka mwa amuna.

Kuzindikira kwa matenda a m'mawere a Paget kumapangidwa ndi katswiri wamaphunziro kudzera pakuyesa kuyezetsa ndikuwunika zizindikilo, monga kupweteka kwa nsagwada, kupsa mtima komanso kusiyanasiyana kwam'deralo komanso kupweteka komanso kuyabwa pachifuwa.

Zizindikiro za matenda a Paget a m'mawere

Zizindikiro za matenda a Paget nthawi zambiri zimachitika mu bere limodzi lokha ndipo zimakonda kupezeka mwa amayi azaka zopitilira 50, zazikulu ndizo:

• Kukwiya kwanuko;
• Ululu wamabele;
• Kutchulidwa kwa dera;
• Kusintha kwa mawonekedwe a nsonga yamabele;
• Ululu ndi kuyabwa mu nsonga ya;
• Kutentha komwe kumachitika;
• Kuumitsa kwa areola;
• Mdima wa tsambalo, munthawi zambiri.

Matenda apamwamba a Paget, pakhoza kukhala khungu pakatikati pa areola, kuwonjezera pakubwezeretsa, kupindika ndi zilonda zam'mimba, chifukwa chake ndikofunikira kuti mankhwala ayambe posachedwa.

Dokotala woyenera kwambiri kuti azindikire ndikuwongolera chithandizo cha matenda a mabere a Paget ndi katswiri wamaphunziro, komabe kuzindikira ndi kuchiza matendawa kungalimbikitsidwenso ndi dermatologist ndi gynecologist. Ndikofunika kuti matendawa apangidwe msanga, chifukwa njira imeneyi imatha kuchitira moyenera, ndi zotsatira zabwino.

Momwe matendawa amapangidwira

Kuzindikira kwa matenda a m'mawere a Paget kumapangidwa ndi dokotala kudzera pakuwunika zizindikilo ndi mawonekedwe a bere la mkazi, kuphatikiza pakuyesa kujambula, monga mawere a ultrasound ndi kujambula kwa maginito, mwachitsanzo. Kuphatikiza apo, mammography imawonetsedwa kuti iwunikenso ngati pali zotupa kapena ma microcalcization m'mawere omwe atha kukhala owonetsa a carcinoma owopsa.

Kuphatikiza pa kuyerekezera kujambula, dokotala nthawi zambiri amapempha kuti apange chimbudzi, kuti atsimikizire mawonekedwe am'maselo, kuphatikiza mayeso a immunohistochemical, omwe amafanana ndi mtundu wa mayeso a labotale momwe kutsimikizika kupezeka kapena kupezeka kwa ma antigen omwe amatha kudziwa matendawa, monga AE1, AE3, CEA ndi EMA omwe ali ndi matenda a Paget a m'mawere.

Kusiyanitsa matenda

Matenda osiyanitsa a matenda a m'mawere a Paget amapangidwa makamaka ndi psoriasis, basal cell carcinoma ndi eczema mwachitsanzo, kusiyanitsidwa kuchokera kumapeto chifukwa chosagwirizana komanso kuyabwa pang'ono. Matendawa atha kupangidwanso moganizira momwe angathandizire, popeza matenda a Paget, chithandizo cham'mutu chimatha kuthetsa zizindikilo koma sichikhala ndi zotsatirapo zake, ndikubwereza.

Kuphatikiza apo, matenda a m'mawere a Paget, atapanga pigment, ayenera kusiyanitsidwa ndi khansa ya khansa, ndipo izi zimachitika makamaka kudzera pakuwunika kwa histopathological, komwe kumachitika kuyesa ma cell am'mawere, ndi immunohistochemistry, momwe kuli kupezeka kwa HMB-45, Ma antian a MelanA ndi S100 mu khansa ya khansa komanso kusowa kwa ma antigen a AE1, AE3, CEA ndi EMA, omwe nthawi zambiri amapezeka mu matenda a Paget a m'mawere, kulibe.

Chithandizo cha matenda a m'mawere a Paget

Chithandizo chomwe dokotala amalemba cha matenda a m'mawere a Paget nthawi zambiri chimakhala chizimba chotsatira ndikutsatira mankhwala a chemotherapy kapena radiation, chifukwa matendawa nthawi zambiri amakhala okhudzana ndi khansa ya khansa. Nthawi zochepa, kuchotsedwa kwa malo ovulala kumatha kuwonetsedwa, kuteteza bere lonselo. Kuzindikira koyambirira ndikofunikira kuti muchepetse kukula kwa matenda, komanso chithandizo cha opaleshoni.

Nthawi zina, adotolo angasankhe kuchita chithandizocho ngakhale atapanda kutsimikiziridwa kuti ali ndi vutoli, posonyeza kugwiritsa ntchito mankhwala apakhungu. Vuto lokhudzana ndi mayendedwe amtunduwu ndikuti mankhwalawa amatha kuchepetsa zizindikilo, komabe sizilepheretsa kukula kwa matendawa.