Momwe mungamvetsetse mayeso a TGO-AST: Aspartate Aminotransferase

Zamkati

• Kodi AST yapamwamba imatanthauza chiyani?
• Ritis chifukwa
• Mayeso akaitanidwa

Kufufuza kwa aspartate aminotransferase kapena oxalacetic transaminase (AST kapena TGO), ndiko kuyesa magazi komwe kumafunsidwa kuti kufufuze zotupa zomwe zimasokoneza magwiridwe antchito a chiwindi, monga hepatitis kapena cirrhosis, mwachitsanzo.

Oxalacetic transaminase kapena aspartate aminotransferase ndi enzyme yomwe imakhalapo m'chiwindi ndipo nthawi zambiri imakwezedwa ngati kuvulala kwa chiwindi kumakhala kwanthawi yayitali, chifukwa imapezeka mkati mwa khungu la chiwindi. Komabe, enzyme iyi imatha kukhalanso mumtima, ndipo itha kugwiritsidwa ntchito ngati chikhomo cha mtima, chomwe chitha kuwonetsa infarction kapena ischemia.

Monga chikhomo cha chiwindi, AST nthawi zambiri imayeza limodzi ndi ALT, chifukwa imatha kukwezedwa nthawi zina, kukhala yosadziwika pachifukwa ichi. O mtengo wowerengera ma enzyme uli pakati pa 5 ndi 40 U / L. a magazi, omwe amasiyana malinga ndi labotale.

Kodi AST yapamwamba imatanthauza chiyani?

Ngakhale mayeso a AST / TGO sakhala achindunji, adokotala amatha kuyitanitsa mayesowa limodzi ndi ena omwe akuwonetsa thanzi la chiwindi, monga muyeso wa gamma-glutamyltransferase (GGT), alkaline phosphatase (ALK) ndipo, makamaka ALT / TGP. Dziwani zambiri za mayeso a ALT.

Kuwonjezeka kwa AST, kapena TGO yayikulu, kumatha kuwonetsa:

• Pachimake kapamba;
• Pachimake tizilombo chiwindi;
• Mowa chiwindi;
• Matenda a chiwindi;
• Abscess mu chiwindi;
• Khansa yoyamba ya chiwindi;
• Kusokonezeka kwakukulu;
• Kugwiritsa ntchito mankhwala omwe amawononga chiwindi;
• Kulephera kwamtima;
• Ischemia;
• Kusokoneza;
• Kutentha;
• Matenda;
• Kutsekeka kwaminyewa ya bile, monga cholangitis, choledocholithiasis;
• Kuvulala kwa minofu ndi hypothyroidism;
• Kugwiritsa ntchito mankhwala monga heparin, salicylates, opiates, tetracycline, thoracic kapena isoniazid

Miyezo yoposa 150 U / L imawonetsa kuwonongeka kwa chiwindi ndipo kupitilira 1000 U / L imatha kuwonetsa matenda a chiwindi omwe amabwera chifukwa chogwiritsa ntchito mankhwala, monga paracetamol, kapena ischemic hepatitis, mwachitsanzo. Kumbali inayi, kutsika kwa mfundo za AST kumatha kuwonetsa kuchepa kwa vitamini B6 kwa anthu omwe amafunikira dialysis.

[mayeso-review-tgo-tgp]

Ritis chifukwa

Chifukwa cha Ritis chimagwiritsidwa ntchito pochizira odwala kuti awone kuchuluka kwa chiwindi chomwe chimawonongeka ndikupanga chithandizo chabwino kwambiri pamkhalidwewo. Chiwerengerochi chimaganizira zofunikira za AST ndi ALT ndipo zikakwera kuposa 1 zimawonetsa kuvulala koopsa, monga matenda a chiwindi kapena khansa ya chiwindi, mwachitsanzo. Zochepera 1 zimatha kukhala gawo lachiwopsezo cha matenda a chiwindi, mwachitsanzo.

Mayeso akaitanidwa

Mayeso a magazi a TGO / AST atha kuyitanidwa ndi dokotala zikafunika kuwunika thanzi la chiwindi, atawona kuti munthuyo ndi wonenepa, ali ndi mafuta m'chiwindi kapena akuwonetsa zizindikilo monga khungu lachikasu, kupweteka mimba yakumanja kapena pobowoka ndi mkodzo wakuda.

Nthawi zina zomwe zingakhale zothandiza kuyesa enzyme iyi atagwiritsa ntchito mankhwala omwe angawononge chiwindi ndikuwunika chiwindi cha anthu omwe amamwa zakumwa zoledzeretsa zambiri.