H2 Olandira Oseketsa

Zamkati

• Kodi H2 Receptor blockers ndi Chiyani?
• Kodi H2 Receptor blockers imagwira ntchito bwanji?
• Kodi Zotsatira Zoyipa za H2 Receptor blockers Ndi Zotani?
• H2 Receptor Blockers vs. Proton Pump Inhibitors (PPIs)
• Njira Zina Zochiritsira
• Funso:
• Yankho:

Mu Epulo 2020, adapempha kuti mitundu yonse yamankhwala ndi owonjezera (OTC) ranitidine (Zantac) zichotsedwe kumsika waku U.S. Malangizowa adapangidwa chifukwa milingo yosavomerezeka ya NDMA, yomwe imayambitsa khansa (yomwe imayambitsa khansa), idapezeka muzinthu zina za ranitidine. Ngati mwalamulidwa ranitidine, lankhulani ndi dokotala wanu za njira zina zoyenera musanayimitse mankhwalawo. Ngati mukumwa OTC ranitidine, lekani kumwa mankhwalawa ndipo lankhulani ndi omwe amakuthandizani pazithandizo zina. M'malo motengera mankhwala osagwiritsidwa ntchito a ranitidine kumalo obwezeretsanso mankhwala, muzitaya malinga ndi malangizo a mankhwalawo kapena kutsatira FDA.

Kodi H2 Receptor blockers ndi Chiyani?

H2 receptor blockers ndi gulu la mankhwala omwe angagwiritsidwe ntchito pochiza zinthu zomwe zimayambitsa asidi m'mimba. Mankhwalawa amapezeka pa kauntala komanso mwa mankhwala. Ovomerezeka a H2 receptor ndi awa:

• nizatidine (Axid)
• famotidine (Pepcid, Pepcid AC)
• cimetidine (Tagamet, Tagamet HB)

Ma H2 receptor blockers amagwiritsidwa ntchito kwambiri pochizira gastritis, kapena m'mimba yotupa, komanso kuchiza zilonda zam'mimba. Zilonda zam'mimba ndi zilonda zopweteka zomwe zimapezeka mkatikati mwa m'mimba, m'mimba, kapena duodenum, lomwe ndi gawo loyamba la m'mimba. Nthawi zambiri zimayamba chifukwa cha kutupa komanso asidi owonjezera m'mimba. Madotolo amathanso kulangiza ma H2 receptor blockers kuti zilonda zam'mimba zisabwerere.

Ma H2 receptor blockers amagwiritsidwanso ntchito kuthana ndi zizindikilo za gastroesophageal Reflux matenda (GERD). GERD ndi mtundu wosatha wa asidi Reflux, womwe umapangitsa kuti acidic m'mimba ibwererenso kummero. Kupezeka kwa asidi wam'mimba pafupipafupi kumatha kukhumudwitsa kum'mero ​​ndikumabweretsa zizindikilo zosasangalatsa, monga kutentha pa chifuwa, mseru, kapena vuto kumeza.

Ma H2 blockers atha kugwiritsidwanso ntchito kuthana ndi zovuta zochepa monga matenda a Zollinger-Ellison, zomwe zimayambitsa kuchuluka kwa asidi m'mimba

Madokotala amathanso kulangiza ma H2 receptor blockers kuti asagwiritse ntchito zilembo. Izi zikutanthauza kugwiritsa ntchito mankhwalawa pochiza vuto lomwe mankhwalawo sanaloledwe kuchiza. Mwachitsanzo, ma H2 receptor blockers atha kugwiritsidwa ntchito kuthana ndi vuto la kapamba kapena kugwiritsidwa ntchito ngati atakumana ndi zovuta, ngakhale sizigwiritsidwe ntchito mwanjira izi.

Kodi H2 Receptor blockers imagwira ntchito bwanji?

Mukatenga cholandilira cha H2, zinthu zomwe zimagwira zimayendera ma receptors ena pamwamba pam'mimba omwe amatulutsa zidulo. Mankhwalawa amaletsa kusintha kwamankhwala ena m'maselo amenewa kuti sangatulutse asidi wambiri. Malinga ndi National Institutes of Health, ma H2 receptor blockers amachepetsa kutulutsa kwa asidi m'mimba munthawi ya maola 24 ndi 70%. Mwa kuchepetsa kuchuluka kwa asidi m'mimba, minofu iliyonse yowonongeka imapatsidwa nthawi kuti ichiritse.

Kodi Zotsatira Zoyipa za H2 Receptor blockers Ndi Zotani?

Zotsatira zoyipa zambiri zomwe zimakhudzana ndi ma H2 receptor blockers ndizochepa ndipo nthawi zambiri zimatsika pomwe munthu amamwa mankhwalawo pakapita nthawi. Ndi 1.5% yokha mwa anthu omwe amasiya kumwa ma H2 receptor blocker chifukwa chazotsatira zake.

Zina mwazovuta zomwe zingachitike ndi H2 receptor blockers ndi monga:

• kudzimbidwa
• kutsegula m'mimba
• kuvuta kugona
• pakamwa pouma
• khungu lowuma
• kupweteka mutu
• kulira m'makutu
• mphuno yothamanga
• kuvuta kukodza

Itanani dokotala wanu ngati muli ndi zizindikiro zina zomwe mukuganiza kuti mwina chifukwa chotenga cholembera cha H2.

Nthawi zambiri, ma H2 receptor blockers amatha kuyambitsa zovuta zina, monga:

• khungu, lotentha, kapena lokulitsa khungu
• kusintha kwa masomphenya
• chisokonezo
• kubvutika
• kuvuta kupuma
• kupuma
• kufinya pachifuwa
• kugunda kwamtima kosasintha
• kuyerekezera zinthu m'maganizo
• Maganizo ofuna kudzipha

Itanani dokotala wanu kapena pitani kuchipatala nthawi yomweyo ngati mukukumana ndi izi.

Ngakhale zotsatira zake zingakhale zoyipa, ma H2 receptor blockers nthawi zambiri amakhala othandizira kwambiri pazinthu zomwe zimayambitsa asidi m'mimba mopitirira muyeso. Inu ndi dokotala wanu mutha kukambirana za zoopsa zomwe zingachitike ndikuwona ngati H2 receptor blockers ndiye njira yabwino kwambiri pachikhalidwe chanu. Simuyenera kusiya kumwa mankhwala anu osalankhula ndi adotolo poyamba.

H2 Receptor Blockers vs. Proton Pump Inhibitors (PPIs)

Proton pump inhibitors (PPIs) ndi mtundu wina wa mankhwala omwe amagwiritsidwa ntchito pochepetsa asidi m'mimba ndikuchiza acid reflux kapena GERD. Zitsanzo za ma PPIs amaphatikizapo esomeprazole (Nexium) ndi pantoprazole (Protonix).

Mankhwala onsewa amagwira ntchito poletsa ndikuchepetsa kutulutsa kwa asidi m'mimba, koma ma PPI amaonedwa kuti ndi olimba komanso mwachangu pochepetsa zidulo zam'mimba. Komabe, ma H2 receptor blockers amachepetsa kwambiri asidi omwe amatulutsidwa madzulo, zomwe zimakonda kuchititsa zilonda zam'mimba. Ichi ndichifukwa chake olandila H2 amalamulidwa makamaka kwa anthu omwe ali ndi zilonda kapena omwe ali pachiwopsezo chotenga. Ma PPI amatchulidwa kawirikawiri kwa anthu omwe ali ndi GERD kapena acid reflux.

Madokotala nthawi zambiri samalimbikitsa kutenga PPI komanso H2 receptor blocker nthawi yomweyo. Ma H2 receptor blockers amatha kusokoneza magwiridwe antchito a PPIs. Ngati zizindikiro zanu za GERD sizikusintha pogwiritsa ntchito PPI, adotolo angavomereze cholandirira H2 m'malo mwake.

Njira Zina Zochiritsira

Ngati muli ndi zilonda zam'mimba kapena GERD, dokotala wanu angakulimbikitseni kuti mupewe kumwa mankhwala enieni komanso kuti musinthe zina ndi zina kuti muchepetse matenda anu.

Ngati muli ndi zilonda zam'mimba, dokotala angakulimbikitseni kuti muchepetse kugwiritsa ntchito mankhwala osokoneza bongo (NSAIDs), monga aspirin ndi ibuprofen. Kugwiritsa ntchito mankhwalawa mobwerezabwereza komanso kwanthawi yayitali kumakulitsa chiopsezo cha matenda am'mimba. Dokotala wanu angakuuzeni kuti mutenge acetaminophen m'malo mwake. Komabe, simuyenera kusiya kumwa mankhwala osalankhula ndi dokotala poyamba.

Kusintha zina ndi zina m'moyo kungathandizenso kuchepetsa zilonda zam'mimba. Izi zikuphatikiza:

• kuchepetsa kumwa mowa
• kupewa zakudya zokometsera
• kuchepetsa nkhawa
• kusiya kusuta

Ngati muli ndi GERD kapena acid reflux, mankhwala azitsitsimutso omwe angachepetse zizindikilo monga:

• kudya zakudya zazing'ono zingapo patsiku m'malo mwazikulu zitatu
• kupewa kumwa mowa, fodya, zakudya ndi zakumwa zomwe zimayambitsa kuyambitsa
• kukweza mutu wa bedi pafupifupi mainchesi 6
• kudya mafuta ochepa
• kupewa kugona pansi kwa maola osachepera awiri mutadya
• kupewa zokhwasula-khwasula musanagone

Lankhulani ndi dokotala ngati zizindikiro zanu sizikusintha ndi mankhwala kapena mankhwala. Mungafunike chithandizo champhamvu kwambiri kapena opaleshoni kuti muchotse zilonda zam'mimba kapena muchepetse Reflux ya asidi.

Muyenera kupita kuchipatala mwachangu ngati izi zikuchitika:

• mumayamba kupweteka m'mimba koipa kwambiri kuposa momwe mumazolowera
• mumayamba kutentha thupi kwambiri
• mumamva kusanza komwe sikumasulidwa mosavuta
• mumayamba chizungulire komanso kupepuka mutu

Izi ndi zizindikiro za zovuta zamatenda am'mimba zomwe zimafunikira kuthandizidwa mwachangu.

Funso:

Kodi pali aliyense amene sayenera kutenga ma H2 receptor blockers?

Yankho:

Odwala okha omwe ali ndi zovuta zoopsa kapena zowopsa kwa ma H2 blocker omwe ayenera kupewa kuwamwa. Gulu la mankhwalawa ndi gawo B pamimba zomwe zikutanthauza kuti ndibwino kumwa mukakhala ndi pakati.