Mlembi: John Stephens
Tsiku La Chilengedwe: 1 Jayuwale 2021
Sinthani Tsiku: 21 Novembala 2024
Anonim
Enteroendocrine Tumors: MEN1 & Insulinoma (β-cells)– Endocrine Pathology | Lecturio
Kanema: Enteroendocrine Tumors: MEN1 & Insulinoma (β-cells)– Endocrine Pathology | Lecturio

Zamkati

Kodi Insulinoma ndi Chiyani?

Insuloma ndi chotupa chaching'ono m'mapapo chomwe chimatulutsa insulin yochulukirapo. Nthawi zambiri, chotupacho sichikhala ndi khansa. Ma insulinomas ambiri amakhala ocheperako masentimita awiri.

Pancreas ndi chiwalo cha endocrine chomwe chili kuseri kwa mimba yanu. Imodzi mwa ntchito zake ndikupanga mahomoni omwe amayang'anira kuchuluka kwa shuga m'magazi anu, monga insulin. Nthawi zambiri, kapamba amasiya kupanga insulini shuga wanu wamagazi akatsika kwambiri. Izi zimalola kuti shuga m'magazi anu abwerere mwakale. Insulinioma ikamapangidwa m'matumbo anu, imapitilizabe kutulutsa insulini, ngakhale shuga lanu la magazi litatsika kwambiri. Izi zitha kubweretsa hypoglycemia yayikulu, kapena shuga wotsika magazi. Hypoglycemia ndi vuto lowopsa lomwe lingayambitse kusawona bwino, mutu wopepuka, ndikukomoka. Ikhozanso kupha moyo.

Insulinioma nthawi zambiri imafunika kuchotsedwa opaleshoni. Chotupacho chikachotsedwa, kuchira kwathunthu kumakhala kotheka.

Kodi Zizindikiro Za Insulinoma Ndi Ziti?

Anthu omwe ali ndi insulinomas samakhala ndi zizindikilo zowonekera nthawi zonse. Zizindikiro zikachitika, zimatha kusiyanasiyana kutengera kukula kwa vutolo.


Zizindikiro zochepa ndizo:

  • kuwona kawiri kapena kusawona bwino
  • chisokonezo
  • nkhawa ndi kukwiya
  • chizungulire
  • kusinthasintha
  • kufooka
  • thukuta
  • njala
  • kunjenjemera
  • kunenepa mwadzidzidzi

Zizindikiro zowopsa za insulinoma zimatha kukhudza ubongo. Zitha kukhudzanso ma adrenal gland, omwe amawongolera kupsinjika ndi kugunda kwa mtima. Nthawi zina, zizindikilo zimawoneka ngati zofanana ndi za khunyu, matenda amitsempha omwe amayambitsa khunyu. Zizindikiro zomwe zimawoneka pamavuto akulu a insulinoma atha kukhala:

  • kupweteka kapena kugwidwa
  • kugunda kwamtima mwachangu (kopitilira 95 kugunda pamphindi)
  • zovuta kukhazikika
  • kutaya chidziwitso kapena kukomoka

Nthawi zina, insulinomas amatha kukula ndikufalikira mbali zina za thupi. Izi zikachitika, mutha kupeza izi:

  • kupweteka m'mimba
  • kupweteka kwa msana
  • kutsegula m'mimba
  • jaundice, kapena chikaso cha khungu ndi maso

Kodi Chimayambitsa Insulinoma Ndi Chiyani?

Madokotala sakudziwa chifukwa chake anthu amatenga insulinomas. Zotupa zimangowonekera popanda chenjezo.


Mukamadya chakudya, kapamba amapanga insulin. Insulini ndi timadzi tomwe timathandiza thupi lanu kusunga shuga wazakudya zanu. Shuga ikangoyamwa, kapamba amasiya kupanga insulin. Kuchita izi nthawi zambiri kumapangitsa kuti shuga azikhala wolimba. Komabe, imatha kusokonezedwa insulinoma ikayamba. Chotupacho chimapitilizabe kutulutsa insulin ngakhale shuga lanu lamagazi litatsika kwambiri. Izi zitha kubweretsa matenda a hypoglycemia, vuto lalikulu lomwe limakhala ndi shuga wotsika kwambiri.

Ndani Ali pachiwopsezo cha Insulinoma?

Insulinomas ndi osowa. Zambiri ndizochepa ndipo zimakhala zochepa kupitirira masentimita awiri. Ndi 10 peresenti yokha ya zotupa izi zomwe zimakhala ndi khansa. Zotupa za khansa zimakonda kupezeka pafupipafupi mwa anthu omwe ali ndi mitundu yambiri ya endocrine neoplasia mtundu 1. Ichi ndi matenda obadwa nawo omwe amayambitsa zotupa m'modzi kapena angapo am'magazi am'magazi. Kuopsa kwa insulinoma kumawonekeranso kukhala kwakukulu kwa iwo omwe ali ndi matenda a von Hippel-Lindau. Mkhalidwe wobadwa nawowu umayambitsa zotupa ndi zotupa kupangira thupi lonse.


Insulinomas imakhudzanso azimayi kuposa amuna. Amakonda kukula mwa anthu azaka zapakati pa 40 ndi 60.

Kodi Insulinoma Imadziwika Bwanji?

Dokotala wanu adzakuyesani magazi kuti muwone shuga ndi magazi anu. Mlingo wochepa wa shuga wamagazi wokhala ndi insulin wochuluka umasonyeza kupezeka kwa insulinoma.

Mayeso amathanso kuwunika:

  • mapuloteni omwe amaletsa kupanga insulin
  • mankhwala omwe amachititsa kuti kapamba atulutse insulini yambiri
  • mahomoni ena omwe amakhudza kupanga insulin

Dokotala wanu akhoza kuyitanitsa kudya maola 72 ngati kuyezetsa magazi kukuwonetsa kuti muli ndi insulinoma. Mudzakhala m'chipatala pamene mukusala kudya kuti dokotala wanu azitha kuyang'anitsitsa kuchuluka kwa shuga wamagazi. Adzakuyezerani shuga m'magazi anu pakatha maola asanu ndi limodzi osachepera. Simungathe kudya kapena kumwa chilichonse kupatula madzi panthawi yachisala. Mutha kukhala ndi shuga wotsika kwambiri wamagazi mkati mwa maola 48 kuyambira kusala kudya ngati muli ndi insulinoma.

Dokotala wanu akhoza kuyesa zambiri kuti atsimikizire matendawa, kuphatikiza MRI kapena CT scan. Mayesowa amathandiza dokotala kudziwa malo omwe insulinoma amakhala komanso kukula kwake.

Endoscopic ultrasound itha kugwiritsidwa ntchito ngati chotupacho sichingapezeke pogwiritsa ntchito CT kapena MRI scan. Pakati pa endoscopic ultrasound, dokotala wanu amalowetsa chubu lalitali, losasunthika mkamwa mwanu mpaka m'mimba ndi m'matumbo ang'onoang'ono. Chitolirocho chimakhala ndi kafukufuku wa ultrasound, yemwe amatulutsa mafunde omveka omwe amatulutsa zithunzi zambiri za kapamba wanu. Insulini ikapezeka, dokotala wanu amatenga pang'ono pang'ono kuti awunike. Izi zitha kugwiritsidwa ntchito kudziwa ngati chotupacho chili ndi khansa.

Kodi Insulinoma Imayendetsedwa Bwanji?

Chithandizo chabwino kwambiri cha insulinoma ndikuchotsa chotupacho. Gawo laling'ono la kapamba amathanso kuchotsedwa ngati pali chotupa chopitilira chimodzi. Izi zimachiritsa vutoli.

Pali mitundu yosiyanasiyana ya maopareshoni yomwe ingachitike kuti ichotse insulinoma. Malo ndi kuchuluka kwa zotupa zimatsimikizira kuti ndi opaleshoni iti yomwe ingagwiritsidwe ntchito.

Kuchita opaleshoni ya laparoscopic ndiye njira yosankhika ngati pali chotupa chimodzi chokha chaching'ono. Imeneyi ndi njira yowopsa, yocheperako. Pakati pa opaleshoni ya laparoscopic, dotolo wanu amapanga zing'onoting'ono m'mimba mwanu ndikulowetsa laparoscope podutsamo. Laparoscope ndi chubu chachitali, chowonda chokhala ndi kuwala kothamanga kwambiri komanso kamera yayitali kutsogolo. Kamera iwonetsa zithunzizo pazenera, kulola dokotalayo kuti aziwona mkati mwa mimba yanu ndikuwongolera zida. Insulini ikapezeka, imachotsedwa.

Gawo la kapamba lingafunikire kuchotsedwa ngati pali ma insulinomas angapo. Nthawi zina, gawo la m'mimba kapena chiwindi limatha kuchotsedwanso.

Nthawi zambiri, kuchotsa insulinoma sikungachiritse vutoli. Izi zimachitika nthawi zambiri zotupa zili ndi khansa. Mankhwala a khansa insulinomas ndi awa:

  • kuchotsa ma radiofrequency, komwe kumagwiritsa ntchito mafunde a wailesi kupha ma cell a khansa mthupi
  • cryotherapy, yomwe imaphatikizapo kugwiritsa ntchito kuzizira kwambiri kuwononga maselo a khansa
  • chemotherapy, yomwe ndi njira yamankhwala yamankhwala othandiza kuwononga maselo a khansa

Dokotala wanu amathanso kukupatsirani mankhwala kuti muchepetse kuchuluka kwa shuga m'magazi ngati opaleshoni siyothandiza.

Kodi Chiyembekezo Chotani Kwa Anthu Omwe Ali ndi Insulinoma?

Kuwona kwa nthawi yayitali kwa anthu omwe ali ndi insulinoma ndikwabwino ngati chotupacho chikuchotsedwa. Pambuyo pa opaleshoni, anthu ambiri amachira popanda zovuta. Komabe, insulinoma imatha kubwerera mtsogolomo. Kubwereza kumakhala kofala kwambiri mwa anthu omwe ali ndi zotupa zingapo.

Anthu ochepa kwambiri amatha kudwala matenda ashuga atachitidwa opaleshoni. Izi zimangochitika pokhapokha zikondamoyo zonse kapena gawo lalikulu la kapamba zichotsedwa.

Zovuta zimapezeka kwambiri mwa anthu omwe ali ndi khansa insulinomas. Izi ndizowona makamaka ngati zotupazo zafalikira ku ziwalo zina. Dokotalayo sangathe kuchotsa zotupa zonse kwathunthu. Poterepa, chithandizo chambiri ndi chithandizo chotsatira chidzakhala chofunikira. Mwamwayi, ma insulinomas ochepa okha ndi omwe ali ndi khansa.

Kodi Insulinoma Ingapewe Bwanji?

Madokotala sakudziwa chifukwa chomwe insulinomas amapangidwira, chifukwa chake palibe njira yodziwikiratu. Komabe, mutha kuchepetsa chiopsezo chokhala ndi hypoglycemia mwa kuchita masewera olimbitsa thupi pafupipafupi komanso kukhala ndi chakudya chopatsa thanzi. Zakudyazi zimayenera kukhala zipatso, ndiwo zamasamba, ndi zomanga thupi. Muthanso kusungitsa kapamba wanu wathanzi mwa kudya nyama yofiira pang'ono ndikusiya kusuta mukasuta.

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