Lupus Anticoagulants

Zamkati

• Kodi zizindikiro za lupus anticoagulants ndi ziti?
• Kusokonekera
• Zogwirizana
• Kodi ndingayezetse bwanji mankhwala a lupus anticoagulants?
• Kuyesa kwa PTT
• Mayeso ena amwazi
• Kodi lupus anticoagulants amathandizidwa bwanji?
• Mankhwala ochepetsa magazi
• Steroids
• Kusinthana kwa plasma
• Kusiya mankhwala ena
• Zosintha m'moyo
• Kuchita masewera olimbitsa thupi nthawi zonse
• Siyani kusuta fodya komanso kumwa pang'ono
• Kuchepetsa thupi
• Chepetsani kudya zakudya zopatsa thanzi za vitamini K
• Maganizo ake ndi otani?

Kodi lupus anticoagulants ndi chiyani?

Lupus anticoagulants (LAs) ndi mtundu wa antibody wopangidwa ndi chitetezo chamthupi chanu. Ngakhale ma antibodies ambiri amalimbana ndi matenda mthupi, ma LA amalimbana ndi maselo athanzi komanso mapuloteni am'magazi.

Amayambitsa phospholipids, zomwe ndizofunikira kwambiri pakhungu. LAs imalumikizidwa ndimatenda amthupi omwe amadziwika kuti antiphospholipid syndrome.

Kodi zizindikiro za lupus anticoagulants ndi ziti?

LAs imatha kuwonjezera ngozi yamagazi. Komabe, ma antibodies amatha kupezeka ndipo samatsogolera ku khungu.

Ngati mukukhala ndi magazi m'modzi mwa mikono kapena miyendo yanu, zizindikilozo zingaphatikizepo izi:

• kutupa m'manja kapena mwendo
• kufiira kapena kusinthika pamanja kapena mwendo wanu
• kupuma movutikira
• kupweteka kapena dzanzi m'manja mwako kapena mwendo

Magazi omwe amapezeka mumtima kapena m'mapapo anu amatha kuyambitsa:

• kupweteka pachifuwa
• thukuta kwambiri
• kupuma movutikira
• kutopa, chizungulire, kapena zonse ziwiri

Kuundana kwamagazi m'mimba mwanu kapena impso kumatha kubweretsa ku:

• kupweteka m'mimba
• ntchafu ululu
• nseru
• kutsegula m'mimba kapena chopondapo chamagazi
• malungo

Kuundana kwa magazi kumatha kuopseza moyo ngati sakuchiritsidwa mwachangu.

Kusokonekera

Magazi ang'onoang'ono am'magazi omwe amachititsidwa ndi LA amatha kupangitsa kuti akhale ndi pakati ndikupangitsa kuti padera liwonongeke. Kuperewera kwapadera kangakhale chizindikiro cha LAs, makamaka ngati zimachitika pambuyo pa trimester yoyamba.

Zogwirizana

Pafupifupi theka la anthu omwe ali ndi ma LA amakhalanso ndi matenda omwe amadziwika kuti ndi lupus.

Kodi ndingayezetse bwanji mankhwala a lupus anticoagulants?

Dokotala wanu atha kuyitanitsa kuyesedwa kwa ma LA ngati muli ndi magazi osafotokozedwa kapena mwakhala ndi padera kangapo.

Palibe mayeso amodzi omwe amathandiza madokotala kuzindikira bwinobwino ma LA. Kuyesedwa kwamagazi kambiri kumafunika kuti muwone ngati LAs ilipo m'magazi anu. Kubwereza kuyesa kumafunikanso pakapita nthawi kuti mutsimikizire kupezeka kwawo. Izi ndichifukwa choti ma antibodies awa amatha kuwonekera ndi matenda, koma amatha pokhapokha matendawa atatha.

Mayeso atha kuphatikiza:

Kuyesa kwa PTT

Kuyesa pang'ono kwa thromboplastin time (PTT) kumayeza nthawi yomwe zimatenga magazi anu kuti awumire. Ikhozanso kuwulula ngati magazi anu ali ndi maantibioantibulantant. Komabe, sizikuwulula ngati mulibe ma LAs.

Ngati zotsatira za mayeso anu zikuwonetsa kupezeka kwa maantibayotiki, muyenera kuyesedwanso. Kuyesanso kawirikawiri kumachitika pafupifupi milungu 12.

Mayeso ena amwazi

Ngati mayeso anu a PTT akuwonetsa kupezeka kwa maantibioantibulant antibodies, dokotala wanu atha kuyitanitsa mitundu ina ya kuyesa magazi kuti ayang'ane zizindikiro za matenda ena. Mayesowa angaphatikizepo:

• mayeso a antiicardiolipin antibody
• nthawi yotseka ya kaolin
• coagulation factor assays
• yesani kuyesa kwa poyizoni wa njoka ya Russell (DRVVT)
• LA-tcheru PTT
• beta-2 glycoprotein 1 antibody test

Izi zonse ndimayeso amwazi omwe alibe chiopsezo chochepa. Mutha kumva kupweteka pang'ono pomwe singano imaboola khungu lanu. Zingamveke kuwawa pambuyo pake. Palinso chiopsezo chochepa chotenga kachilombo kapena kutuluka magazi, monga kuyesa magazi.

Kodi lupus anticoagulants amathandizidwa bwanji?

Sikuti aliyense amene amalandira matenda a LA amafunikira chithandizo. Ngati mulibe zizindikiro ndipo simunakhalepo ndi magazi oundana m'mbuyomu, dokotala wanu akhoza kukupatsani chithandizo pakadali pano, bola mukamakhala bwino.

Ndondomeko zamankhwala zimasiyana malinga ndi munthu.

Mankhwala a LA akuphatikizapo:

Mankhwala ochepetsa magazi

Mankhwalawa amathandiza kupewa magazi kuundana popondereza chiwindi chanu kupanga vitamini K, yomwe imathandizira kuundana kwa magazi. Odwala magazi wamba amaphatikizapo heparin ndi warfarin. Dokotala wanu amathanso kukupatsani aspirin. Mankhwalawa amaletsa kugwira ntchito kwa ma platelet m'malo mopondereza kupanga vitamini K.

Ngati dokotala wanu akupatsani mankhwala ochepetsa magazi, magazi anu amayesedwa nthawi ndi nthawi ngati alipo ma antibodies a cardiolipin ndi beta-2 glycoprotein 1. Ngati zotsatira zanu zikuwonetsa kuti ma antibodies apita, mutha kusiya kumwa mankhwala. Komabe, izi ziyenera kuchitidwa pokhapokha mutakambirana ndi dokotala wanu.

Anthu ena omwe ali ndi ma LA amafunikira kokha kutenga owonda magazi kwa miyezi ingapo. Anthu ena amafunika kupitiriza kumwa mankhwala kwa nthawi yayitali.

Steroids

Steroids, monga prednisone ndi cortisone, imatha kuletsa chitetezo chamthupi chanu kupanga ma antibodies a LA.

Kusinthana kwa plasma

Kusinthana kwa plasma ndi njira yomwe makina amalekanitsira plasma yanu yamagazi - yomwe ili ndi ma LA - kuchokera kumaselo anu ena amwazi. Plasma yomwe ili ndi LA imalowetsedwa ndi plasma, kapena cholowa m'malo mwa plasma, yomwe ilibe ma antibodies. Izi zimatchedwanso plasmapheresis.

Kusiya mankhwala ena

Mankhwala ena wamba amatha kuyambitsa LA. Mankhwalawa ndi awa:

• mapiritsi olera
• Zoletsa za ACE
• quinine

Lankhulani ndi dokotala wanu za mankhwala aliwonse omwe mukumwa kuti muwone ngati atha kuyambitsa LA. Ngati muli, inu ndi dokotala mutha kukambirana ngati zili bwino kuti musiye kugwiritsa ntchito.

Zosintha m'moyo

Pali kusintha kosavuta kwa moyo komwe mungapange komwe kungathandizenso kuwongolera ma LA, kaya mukumwa mankhwala kapena ayi. Izi zikuphatikiza:

Kuchita masewera olimbitsa thupi nthawi zonse

Kuchita masewera olimbitsa thupi komanso kuyenda kumawonjezera magazi. Izi zikutanthauza kuti zimathandizanso kupewa magazi. Pezani njira yomwe mumakonda yochitira masewera olimbitsa thupi ndipo muzichita izi pafupipafupi. Sichiyenera kukhala chovuta. Kungoyenda bwino tsiku lililonse kumatha kuyambitsa magazi.

Siyani kusuta fodya komanso kumwa pang'ono

Kusiya kusuta ndikofunikira ngati muli ndi LA. Nicotine imayambitsa mitsempha yanu yamagazi, yomwe imabweretsa kuundana.

Kuyesedwa kwachipatala kwawonetsa kuti kumwa kwambiri mowa kumalumikizananso ndikupanga magazi.

Kuchepetsa thupi

Maselo amafuta amapanga zinthu zomwe zingalepheretse magazi kuundana monga akuyenera. Ngati mukulemera kwambiri, magazi anu amatha kunyamula zinthu zambiri.

Chepetsani kudya zakudya zopatsa thanzi za vitamini K

Zakudya zambiri zomwe zili ndi vitamini K wambiri ndizabwino kwa inu, koma zimathandiza kupanga magazi.

Ngati muli ndi oonda magazi, kudya zakudya zokhala ndi vitamini K ndizosavomerezeka ndi mankhwala anu. Zakudya zomwe zili ndi vitamini K wambiri ndi monga:

• burokoli
• letisi
• sipinachi
• katsitsumzukwa
• prunes
• parsley
• kabichi

Maganizo ake ndi otani?

Nthawi zambiri, kuwundana magazi komanso zisonyezo za LAs zimatha kuwongoleredwa ndi chithandizo.

Malingana ndi kafukufuku wa 2002, amayi omwe amachiritsidwa ndi matenda a antiphospholipid - omwe nthawi zambiri amakhala ndi aspirin yaing'ono ndi heparin - amakhala ndi mwayi wokwanira 70% wokhala ndi pakati mpaka kumapeto.