Ma monocyte: ndi chiyani komanso malingaliro ake

Zamkati

• Ma monocyte apamwamba
• Ma monocyte ochepa
• Malingaliro owonetsera

Ma monocyte ndi gulu lama cell amthupi omwe amateteza thupi ku matupi akunja, monga ma virus ndi bacteria. Amatha kuwerengedwa kudzera m'mayeso amwazi omwe amatchedwa leukogram kapena kuwerengera kwathunthu kwamagazi, komwe kumabweretsa kuchuluka kwa maselo achitetezo mthupi.

Ma monocyte amapangidwa m'mafupa ndipo amayenda kwa maola ochepa, ndipo amapita kumatenda ena, komwe amasiyanitsa, kulandira dzina la macrophage, lomwe lili ndi mayina osiyanasiyana kutengera minofu yomwe imapezeka: Maselo a Kupffer, m'chiwindi, microglia, m'manjenje, ndi maselo a Langerhans mu epidermis.

Ma monocyte apamwamba

Kuwonjezeka kwa ma monocyte, omwe amatchedwanso monocytosis, nthawi zambiri kumawonetsa matenda opatsirana, monga chifuwa chachikulu. Kuphatikiza apo, pakhoza kukhala kuwonjezeka kwa kuchuluka kwa monocyte chifukwa cha ulcerative colitis, matenda a protozoal, matenda a Hodgkin, myelomonocytic leukemia, matenda angapo a myeloma ndi autoimmune monga lupus ndi nyamakazi.

Kuwonjezeka kwa ma monocyte sikumayambitsa zizindikilo, kuzindikirika pokhapokha pakuyeza magazi, kuchuluka kwamagazi. Komabe, pakhoza kukhala zizindikilo zokhudzana ndi zomwe zimayambitsa monocytosis, ndipo ziyenera kufufuzidwa ndikuchiritsidwa malinga ndi zomwe adokotala ananena. Mvetsetsani kuchuluka kwake kwa magazi ndi zomwe amapangira.

Ma monocyte ochepa

Miyezo ya monocyte ikakhala yotsika, vuto lotchedwa monocytopenia, nthawi zambiri limatanthauza kuti chitetezo chamthupi chimachepa, monga momwe zimakhalira ndi matenda amwazi, mankhwala a chemotherapy komanso mavuto am'mafupa, monga aplastic anemia and leukemia. Kuphatikiza apo, matenda opatsirana pakhungu, kugwiritsa ntchito corticosteroids ndi matenda a HPV kungayambitsenso kuchepa kwa monocyte.

Maonekedwe omwe ali pafupi ndi 0 a monocyte m'magazi ndi osowa ndipo, akachitika, atha kutanthauza kupezeka kwa MonoMAC Syndrome, omwe ndi matenda amtundu womwe amadziwika ndi kusapezeka kwa ma monocyte ndi mafupa, omwe zingayambitse matenda, makamaka pakhungu. Pakadali pano, mankhwala amachitidwa ndi mankhwala olimbana ndi matenda, monga maantibayotiki, ndipo kungafunikirenso kupangira mafuta m'mafupa kuti athetse vuto la majini.

Malingaliro owonetsera

Malingaliro ake amatha kusiyanasiyana malinga ndi labotale, koma nthawi zambiri imakhala yofanana ndi 2 mpaka 10% ya leukocyte yonse kapena pakati pa 300 ndi 900 monocyte pa mm³ wamagazi.

Mwambiri, kusintha kwamaselo amenewa sikuyambitsa zizindikilo mwa wodwala, yemwe amangomva zisonyezo za matenda zomwe zimayambitsa kuchuluka kapena kutsika kwa monocytes. Kuphatikiza apo, nthawi zina wodwalayo amangopeza kuti pali zosintha mukamayesa magazi pafupipafupi.