Neurofibromatosis: ndi chiyani, mitundu, zoyambitsa ndi chithandizo

Zamkati

• Mitundu yayikulu ya neurofibromatosis
• Zomwe zimayambitsa neurofibromatosis
• Momwe mankhwalawa amachitikira

Matenda a Neurofibromatosis, omwe amadziwikanso kuti Von Recklinghausen's disease, ndi matenda obadwa nawo omwe amadziwonekera azaka zapakati pa 15 ndipo amachititsa kukula kwakanthawi kwaminyewa yamanjenje mthupi lonse, ndikupanga timagulu ting'onoting'ono ndi zotupa zakunja, zotchedwa neurofibromas.

Nthawi zambiri, neurofibromatosis ndiyabwino ndipo siyimakhala pachiwopsezo chilichonse, komabe, chifukwa zimayambitsa kuwonekera kwa zotupa zakunja, zimatha kubweretsa kusokonezeka kwa thupi, zomwe zimapangitsa kuti anthu omwe akukhudzidwawo akufuna kuchitidwa opaleshoni kuti awachotse.

Ngakhale neurofibromatosis ilibe mankhwala, chifukwa zotupa zimatha kubwerera, chithandizo chakuchita opareshoni kapena chithandizo chama radiation chitha kuyesedwa kuti muchepetse kukula kwa zotupazo ndikupangitsa kuti khungu lizioneka lokongola.

Mitundu yayikulu ya neurofibromatosis

Neurofibromatosis ikhoza kugawidwa m'mitundu itatu:

• Neurofibromatosis mtundu 1: chifukwa cha kusintha kwa chromosome 17 komwe kumachepetsa kutulutsa kwa neurofibromine, puloteni yomwe imagwiritsidwa ntchito ndi thupi popewa zotupa. Mtundu wa neurofibromatosis amathanso kuyambitsa kutaya kwamaso ndi kusowa mphamvu;
• Neurofibromatosis mtundu 2: amayamba chifukwa cha kusintha kwa chromosome 22, kuchepa kwa merlina, puloteni ina yomwe imaletsa kukula kwa zotupa mwa anthu athanzi. Mtundu wa neurofibromatosis ungayambitse kumva;
• Schwannomatosis: Ndiwo mtundu wosowa kwambiri wamatenda momwe zotupa zimakhalira mu chigaza, msana wamtsempha kapena zotumphukira. Nthawi zambiri, zizindikilo zamtunduwu zimapezeka azaka zapakati pa 20 ndi 25.

Kutengera mtundu wa neurofibromatosis, zizindikilo zimatha kusiyanasiyana. Chifukwa chake, onani zodziwika bwino zamtundu uliwonse wa neurofibromatosis.

Zomwe zimayambitsa neurofibromatosis

Neurofibromatosis imayambitsidwa ndi kusintha kwa majini m'matenda ena, makamaka chromosome 17 ndi chromosome 22. Kuphatikiza apo, matenda osowa a Schwannomatosis akuwoneka kuti amayamba chifukwa cha kusintha kwamatenda ena monga SMARCB1 ndi LZTR. Mitundu yonse yasinthidwa ndiyofunikira poletsa kupanga zotupa ndipo, chifukwa chake, zikakhudzidwa, zimayambitsa kuwonekera kwa zotupa zomwe zimakhala ndi neurofibromatosis.

Ngakhale kuti ambiri omwe amapezeka ndi matendawa amapatsira kuchokera kwa makolo kupita kwa ana, palinso anthu omwe mwina sanakhalepo ndi matenda m'banjamo.

Momwe mankhwalawa amachitikira

Chithandizo cha neurofibromatosis chitha kuchitidwa kudzera pakuchita opareshoni kuti muchotse zotupa zomwe zikukakamiza ziwalo kapena kugwiritsa ntchito mankhwala a radiation kuti achepetse kukula kwawo. Komabe, palibe chithandizo chotsimikizira kuchiritsidwa kapena chomwe chimalepheretsa zotupa zatsopano.

Pazovuta kwambiri, momwe wodwala amakhala ndi khansa, mwina pangafunike kulandira chithandizo ndi chemotherapy kapena mankhwala a radiation omwe amaperekedwa pa zotupa zoyipa. Dziwani zambiri za Chithandizo cha neurofibromatosis.