West syndrome: ndi chiyani, zizindikiro ndi chithandizo

Zamkati

• Zinthu zazikulu
• Zomwe zimayambitsa West syndrome
• Momwe mankhwalawa amachitikira
• Kodi West syndrome imachiritsidwa?

West Syndrome ndi matenda osowa omwe amadziwika ndi khunyu kawirikawiri, omwe amapezeka kwambiri pakati pa anyamata ndipo amayamba kudziwonetsa mchaka choyamba cha moyo wa mwanayo. Nthawi zambiri, zovuta zoyambirira zimachitika pakati pa miyezi 3 mpaka 5 ya moyo, ngakhale matendawa amatha kupangidwa mpaka miyezi 12.

Pali mitundu itatu yamatendawa, yowonetsa, idopathic ndi cryptogenic, ndipo mwazizindikiro mwanayo ali ndi chifukwa monga mwana yemwe wakhala akupuma kwa nthawi yayitali; cryptogenic ndipamene imayambitsidwa ndi matenda ena amubongo kapena zachilendo, ndipo idiopathic ndipamene chifukwa chake sichingadziwike ndipo mwana atha kukula bwino pagalimoto, monga kukhala pansi ndi kukwawa.

Zinthu zazikulu

Zowoneka bwino za matendawa zimachedwa kukula kwa psychomotor development, kugwa kwamatsenga tsiku lililonse (nthawi zina kuposa 100), kuwonjezera pamayeso monga electroencephalogram yomwe imatsimikizira kukayikirako. Pafupifupi 90% ya ana omwe ali ndi matendawa nthawi zambiri amakhala ndi kuchepa kwamaganizidwe, autism komanso kusintha kwamlomo ndizofala. Bruxism, kupuma pakamwa, kutsekemera kwa mano ndi gingivitis ndizomwe zimasintha kwambiri mwa ana awa.

Chofala kwambiri ndichakuti wonyamula matendawa amakhudzidwanso ndi zovuta zina zamaubongo, zomwe zimalepheretsa chithandizo, kukhala ndi chitukuko choipa, kukhala kovuta kuwongolera. Komabe, pali ana ngati atachira kwathunthu.

Zomwe zimayambitsa West syndrome

Zomwe zimayambitsa matendawa, zomwe zimatha kuyambitsidwa ndi zinthu zingapo, sizidziwikiratu, koma zomwe zimafala kwambiri ndimavuto pakubadwa, monga kusowa kwa mpweya waubongo panthawi yobereka kapena atangobereka kumene, ndi hypoglycemia.

Zina zomwe zimawoneka kuti zimakonda matendawa ndi kusokonekera kwa ubongo, kusakhwima msana, sepsis, matenda a Angelman, stroke, kapena matenda monga rubella kapena cytomegalovirus panthawi yapakati, kuphatikiza kugwiritsa ntchito mankhwala osokoneza bongo kapena kumwa mowa kwambiri panthawi yapakati. Chifukwa china ndicho kusintha kwa jini Bokosi lanyumba lothandizidwa ndi Aristaless (ARX) pa X chromosome.

Momwe mankhwalawa amachitikira

Chithandizo cha West Syndrome chiyenera kuyambika mwachangu, chifukwa nthawi yogwa khunyu ubongo umatha kuwonongeka kosasinthika, ndikuwononga thanzi la mwana ndikukula.

Kugwiritsa ntchito mankhwala monga adrenocorticotrophic hormone (ACTH) ndi njira ina yothandizira, kuwonjezera pa physiotherapy ndi hydrotherapy. Mankhwala monga sodium valproate, vigabatrin, pyridoxine ndi benzodiazepines amatha kukupatsani dokotala.

Kodi West syndrome imachiritsidwa?

M'milandu yosavuta, pomwe West syndrome siyokhudzana ndi matenda ena, ikapanda kutulutsa zizindikilo, ndiye kuti, chifukwa chake sichikudziwika, kumadziwika kuti ndi idiopathic West syndrome komanso mwana akamalandira chithandizo koyambirira, posachedwa pakagwa mavuto oyamba kuwoneka, matendawa amatha kuwongoleredwa, ali ndi mwayi wochiritsidwa, osafunikira chithandizo chamthupi, ndipo mwanayo amatha kukhala ndi chitukuko chabwinobwino.

Komabe, mwana akakhala ndi matenda ena obwera chifukwa chake komanso ngati thanzi lake silili bwino, matendawa sangachiritsidwe, ngakhale chithandizo chake chimatha kumulimbikitsa. Munthu woyenera kuwonetsa kuti thanzi la mwanayo ndi dokotala wamankhwala omwe, atawunika mayeso onse, athe kuwonetsa mankhwala oyenera komanso kufunikira kwa magawo olimbikitsira psychomotor ndi physiotherapy.