Mlembi: Marcus Baldwin
Tsiku La Chilengedwe: 17 Kuni 2021
Sinthani Tsiku: 16 Novembala 2024
Anonim
Use of Stiripentol in Dravet Syndrome with Dr. Ben Menachem,
Kanema: Use of Stiripentol in Dravet Syndrome with Dr. Ben Menachem,

Zamkati

Stiripentol imagwiritsidwa ntchito limodzi ndi clobazam (Onfi®) kuwongolera kugwa kwa akulu ndi ana azaka zapakati pa 2 kapena kupitilira apo omwe ali ndi matenda a Dravet (matenda omwe amayamba adakali ana ndipo amayamba kukomoka ndipo pambuyo pake atha kubweretsa kuchedwa kwachitukuko ndikusintha pakudya, kuyerekeza, komanso kuyenda). Stiripentol ali mgulu la mankhwala otchedwa anticonvulsants. Zimagwira ntchito pochepetsa chisangalalo chachilendo muubongo.

Stiripentol imabwera ngati kapisozi ndi ufa wamkamwa kuti kuyimitsidwa kutenge pakamwa. Nthawi zambiri amatengedwa kawiri kapena katatu patsiku pakudya. Tengani stiripentol mozungulira nthawi imodzimodzi tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani stiripentol ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza makapisozi lonse ndi madzi; osathyola kapena kutsegula.

Ngati mukumwa ufa, muyenera kusakaniza ndi madzi nthawi yomweyo musanamwe. Dokotala angakuwuzeni mapaketi angati amtundu wa stiripentol ufa womwe mungagwiritse ntchito komanso kuchuluka kwa madzi osakanikirana nawo. Werengani mosamala malangizo a opanga omwe amafotokoza momwe mungasakanizire ndi kumwa mankhwala a stiripentol. Onetsetsani kuti mufunse wamankhwala kapena dokotala wanu ngati muli ndi mafunso okhudza momwe mungasakanizire kapena kumwa mankhwalawa.


Stiripentol imayang'anira matenda anu koma siyichiritsa. Pitirizani kumwa mankhwala a stiripentol ngakhale mutakhala bwino. Osasiya kumwa mankhwala osakwiya popanda kuyankhula ndi dokotala, ngakhale mutakumana ndi zovuta monga kusintha kwakanthawi kwamakhalidwe kapena malingaliro. Ngati mwasiya mwadzidzidzi kumwa mankhwala a stiripentol, matendawo angakule kwambiri. Dokotala wanu mwina amachepetsa mlingo wanu pang'onopang'ono.

Dokotala wanu kapena wamankhwala amakupatsirani pepala lazidziwitso za wopanga (Medication Guide) mukayamba mankhwala ndi stiripentol ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanayambe kumwa mankhwala,

  • uzani dokotala ndi wamankhwala ngati muli ndi matupi awo sagwirizana ndi mankhwala a stiripentol, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapiso a stiripentol kapena ufa wamkamwa woyimitsidwa. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: caffeine kapena mankhwala omwe ali ndi caffeine (Cafcit, Excedrin, ku Cafergot, ena); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); clopidogrel (Plavix); diazepam (Valium); glyburide (Diabeta, Glynase); methotrexate (Otrexup, Rasuvo, Xatmep); midazolam (Seizalam); phenobarbital; phenytoin (Dilantin, Phenytek); prazosin (Minipress); quinidine (mu Nuedexta); rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); mankhwala ogonetsa, mapiritsi ogona, kapena zotontholetsa; mankhwala opatsirana (Zoloft); theophylline (Elixophyllin, Theo-24, Theochron); thiotepa (Tepadina); kapena triazolam (Halcion). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi stiripentol, chifukwa chake onetsetsani kuti mumauza dokotala za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
  • muuzeni dokotala ngati mwakhalapo ndi vuto lakukhumudwa, mavuto amisala, kapena malingaliro ofuna kudzipha kapena machitidwe kapena impso kapena matenda a chiwindi.
  • Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukamamwa mankhwala a stiripentol, itanani dokotala wanu.
  • muyenera kudziwa kuti stiripentol imatha kukupangitsani kukhala ozunguzika kapena kuwodzera ndipo zingakhudze mgwirizano wanu. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
  • Funsani dokotala wanu za zakumwa zoledzeretsa pamene mukumwa mankhwala a stiripentol. Mowa umatha kupangitsa zotsatira zoyipa kuchokera ku stiripentol kukulira.
  • ngati muli ndi phenylketonuria (PKU, mkhalidwe wobadwa nawo momwe muyenera kudya chakudya chapadera kuti muchepetse kuchepa kwamaganizidwe), muyenera kudziwa kuti stiripentol ufa wothira umakomedwa ndi aspartame yomwe imapanga phenylalanine.
  • muyenera kudziwa kuti thanzi lanu lamisala lingasinthe m'njira zosayembekezereka ndipo mutha kudzipha (kuganiza zodzipweteka kapena kudzipha nokha kapena kukonzekera kapena kuyesa kutero) mukamamwa mankhwala a stiripentol. Chiwerengero chochepa cha achikulire ndi ana azaka 5 zakubadwa kapena kupitilira (pafupifupi 1 mwa anthu 500) omwe adatenga ma anticonvulsants, monga stiripentol, kuti athetse zovuta zosiyanasiyana panthawi yamaphunziro azachipatala adadzipha panthawi yomwe amathandizidwa. Ena mwa anthuwa adayamba kudzipha sabata limodzi atayamba kumwa mankhwalawo. Inu ndi dokotala wanu muwona ngati kuopsa kokumwa mankhwala a anticonvulsant ndiokulirapo kuposa kuopsa kosamwa mankhwalawo. Inu, banja lanu, kapena amene amakusamalirani muyenera kuyimbira dokotala nthawi yomweyo mukakumana ndi izi: mantha; kusakhazikika kapena kusakhazikika; kukwiya kwatsopano kapena kukulira, nkhawa, kapena kukhumudwa; kuchita zofuna zawo; kuvuta kugona kapena kugona; aukali, aukali, kapena achiwawa; mania (kukwiya, kusangalala modabwitsa); kuganiza zodzipweteka kapena kudzipha, kapena kukonzekera kapena kuyesa kutero; kapena kusintha kwina kulikonse pamakhalidwe kapena malingaliro. Onetsetsani kuti banja lanu kapena amene akukusamalirani akudziwa zomwe zingakhale zovuta kuti athe kuyimbira dokotala ngati mukulephera kupeza chithandizo chanokha.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Stiripentol angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kugona
  • kutopa
  • mavuto ndi mgwirizano
  • kugwedezeka kosalamulirika kwa gawo lina la thupi
  • kutayika kwa minofu
  • zovuta kuyankhula
  • kutsitsa
  • nseru
  • kusanza
  • kusintha kwa kulemera
  • kupweteka pamodzi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

  • chifuwa, zilonda zapakhosi, malungo, kuzizira, kapena zizindikilo zina za matenda
  • kuvulaza kapena kutuluka mwachilendo
  • magazi mkodzo kapena ndowe

Stiripentol imatha kuyambitsa njala komanso kuchepa thupi. Mukawona kuti mwana wanu akutaya thupi, itanani dokotala wanu.Dokotala wanu adzawona kukula kwa mwana wanu mosamala. Lankhulani ndi dokotala wanu ngati muli ndi nkhawa zakukula kapena kulemera kwa mwana wanu akamamwa mankhwalawa.


Stiripentol ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha komanso kutalikirana ndi {kuwala,} kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira ku Stiripentol.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Mgwirizano®
Idasinthidwa Komaliza - 12/15/2018

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