Kuyesa kwayekhayokha mwachindunji komanso kosawonekera: ndi chiyani komanso ndi chiyani

Zamkati

• Momwe mayeso amachitikira
• Zomwe zotsatira zake zikutanthauza

Kuyesa kwa coomb ndi mtundu wa kuyesa magazi komwe kumawunika kupezeka kwa ma antibodies omwe amalimbana ndi maselo ofiira, kuwononga kwawo ndipo mwina kumabweretsa mtundu wa magazi m'thupi wotchedwa hemolytic.

Pali mitundu iwiri yayikulu ya mayeso awa, omwe ndi awa:

• Mayeso a Direct Coombs: amayesa mwachindunji maselo ofiira, kuwunika ma antibodies omwe amaphatikizidwa ndi khungu lofiira la magazi komanso ngati ma antibodies awa amachokera m'thupi la munthuyo kapena amalandiridwa ndi kuthiridwa magazi. Kuyesaku kumachitika nthawi zambiri kuti azindikire kuperewera kwama hemolytic anemias - Onani zomwe zingasonyeze kuchepa kwa magazi m'thupi;
• Mayeso a Coombs osalunjika: amayesa seramu yamagazi, kuzindikira ma antibodies omwe amapezeka pamenepo, ndipo nthawi zambiri amapemphedwa ngati atapatsidwa magazi, kuti awonetsetse kuti magazi omwe aperekedwe amagwirizana ndi wolandirayo.

Kuphatikiza pa kuchepa kwa magazi m'thupi, kuyezaku kungathandizenso kuzindikira matenda ena omwe amakhudza ma cell a magazi monga leukemia, lupus, mononucleosis ndi fetal erythroblastosis, yomwe imadziwikanso kuti hemolytic matenda a wakhanda, komanso kuzindikira kuwopsa kwakusintha magazi. Dziwani zambiri za fetus erythroblastosis.

Momwe mayeso amachitikira

Kuyesa kwa Coombs kumachitika kuchokera pachitsanzo cha magazi, chomwe chimayenera kusonkhanitsidwa mu labotale yoyeserera zamankhwala. Magazi omwe asonkhanitsidwawo amatumizidwa ku labotale, komwe mayeso a Coombs achindunji kapena osadziwika adzachitika, kutengera cholinga.

Poyesa mwachindunji kwa Coombs, reombenti ya Coombs imawonjezeredwa m'magazi a wodwalayo, kulola kuwonera ma antibodies omwe atha kulumikizidwa ndi maselo ofiira. Poyesa kosalunjika kwa Coombs, magazi amatengedwa ndikupanga centrifuged, kulekanitsa maselo ofiira am'madzi a seramu, omwe amakhala ndi ma antibodies. Ku seramu, maselo ofiira omwe amalembedweratu ndi ma antibodies amawonjezedwa kuti awone ngati pali ma autoantibodies omwe amapezeka mu seramu, chifukwa chake, m'magazi a wodwalayo.

Kuti muchite mayeso a Coombs, palibe kukonzekera kofunikira, koma mankhwala ena amatha kusokoneza zotsatira zake, chifukwa chake ndikofunikira kudziwitsa adotolo momwe angagwiritsire ntchito kuti malangizo aperekedwe pakuimitsidwa kwake.

Zomwe zotsatira zake zikutanthauza

Zotsatira za kuyesa kwa Coombs ndizosavomerezeka ngati kulibe antibody yemwe amachititsa kuwonongeka kwa ma globes ofiira, ndichifukwa chake amawonedwa ngati zotsatira zabwinobwino.

Komabe, zotsatira zake zikakhala kuti zili ndi kachilombo, zikutanthauza kuti pali antibody m'magazi ndipo, chifukwa chake, ngati zotsatirazo zili zabwino poyesa kwa Coombs kumatanthauza kuti munthuyo akhoza kukhala ndi matenda monga:

• Autoimmune hemolytic magazi m'thupi;
• Kutenga ndi Mycoplasma sp.;
• Chindoko;
• Khansa ya m'magazi;
• Lupus erythematosus;
• Mononucleosis.

Pankhani yoyesedwa kosawonekera kwa Coombs, zotsatira zake zabwino zimatanthauza kuti munthuyo ali ndi antibody yemwe angayambitse kuundana polandira mtundu wina wamagazi, chifukwa chake, ndikofunikira kusamala popanga magazi.

Mulimonsemo, nthawi zonse kumakhala kofunikira kuti zotsatira ziwunikidwe ndi adotolo omwe adafunsa, chifukwa mbiri yamunthuyo ingasinthe zotsatirazi.