TRT: Kulekanitsa Zowona ndi Zopeka
Zamkati
- Kodi TRT ndi chiyani?
- Nchifukwa chiyani T amachepetsa ndi ukalamba?
- Ndingadziwe bwanji ngati ndili ndi T otsika?
- Kodi TRT imayendetsedwa bwanji?
- Kodi TRT imagwiritsidwa ntchito bwanji ngati mankhwala?
- Kodi ntchito zosagwiritsa ntchito mankhwala za TRT ndi ziti?
- Zimawononga ndalama zingati TRT?
- Khalani ovomerezeka (komanso otetezeka)
- Kodi pali zoopsa zilizonse zokhudzana ndi TRT?
- Mfundo yofunika
Kodi TRT ndi chiyani?
TRT ndichidule cha mankhwala obwezeretsa testosterone, omwe nthawi zina amatchedwa androgen m'malo mwake. Amagwiritsidwa ntchito makamaka pochiza masitepe otsika a testosterone (T), omwe amatha kuchitika ndi msinkhu kapena chifukwa chazachipatala.
Koma zikuchulukirachulukira pazosagwiritsa ntchito zamankhwala, kuphatikiza:
- kulimbikitsa kugonana
- kukwaniritsa mphamvu zambiri
- kumanga minofu yolimbitsa thupi
Kafukufuku wina akuwonetsa kuti TRT itha kukuthandizirani kukwaniritsa zina mwa izi. Koma pali mapanga ena. Tiyeni tilowe mu zomwe zimachitika kwenikweni pamasinkhu anu a T mukamakalamba komanso zomwe mungayembekezere kuchokera ku TRT.
Nchifukwa chiyani T amachepetsa ndi ukalamba?
Thupi lanu mwachilengedwe limapanga T zochepa mukamakalamba. Malinga ndi nkhani mu American Family Physician, kuchuluka kwa T kwamwamuna kumatsika ndi pafupifupi 1 mpaka 2 peresenti chaka chilichonse.
Izi zonse ndi gawo lazinthu zachilengedwe zomwe zimayambira kumapeto kwa 20s kapena 30s oyambirira:
- Mukamakalamba, machende anu amatulutsa T.
- Machende otsika T amachititsa kuti hypothalamus yanu ipange timadzi tating'onoting'ono totsitsa gonadotropin (GnRH).
- Kutsika GnRH kumapangitsa kuti pituitary gland yanu ichepetse mahomoni ochepetsa luteinizing (LH).
- Kutsika kwa LH kumabweretsa kutsika konse kwa kupanga T.
Kutsika pang'onopang'ono kwa T nthawi zambiri sikuyambitsa zizindikilo zowonekera. Koma kutsika kwakukulu kwa milingo ya T kumatha kuyambitsa:
- kugonana kotsika
- zochepa zochepa zokha
- Kulephera kwa erectile
- kutsitsa kuchuluka kwa umuna kapena voliyumu
- kuvuta kugona
- kutayika kwachilendo kwa kuchepa kwa minofu ndi mafupa
- kunenepa kosadziwika
Ndingadziwe bwanji ngati ndili ndi T otsika?
Njira yokhayo yodziwira ngati mulidi ndi otsika T ndi kuwona wopereka chithandizo chazoyeserera pamlingo wa testosterone. Uku ndi kuyesa magazi kosavuta, ndipo opereka ambiri amafunikira asanalembe TRT.
Mungafunike kuyesa kangapo chifukwa ma T amakhudzidwa ndi zinthu zosiyanasiyana, monga:
- zakudya
- mulingo wathanzi
- nthawi yamasiku mayeso atha
- mankhwala ena, monga anticonvulsants ndi steroids
Nayi kuwonongeka kwa mulingo wa T wamwamuna wamkulu kuyambira zaka 20:
Zaka (m'zaka) | Mulingo wa T mu nanograms pa mamililita (ng / ml) |
---|---|
20–25 | 5.25–20.7 |
25–30 | 5.05–19.8 |
30–35 | 4.85–19.0 |
35–40 | 4.65–18.1 |
40–45 | 4.46–17.1 |
45–50 | 4.26–16.4 |
50–55 | 4.06–15.6 |
55–60 | 3.87–14.7 |
60–65 | 3.67–13.9 |
65–70 | 3.47–13.0 |
70–75 | 3.28–12.2 |
75–80 | 3.08–11.3 |
80–85 | 2.88–10.5 |
85–90 | 2.69–9.61 |
90–95 | 2.49–8.76 |
95–100+ | 2.29–7.91 |
Ngati magulu anu a T ali ochepa pang'ono pazaka zanu, mwina simukusowa TRT.Ngati ali otsika kwambiri, omwe amakupatsani mwayi atha kuyesa zina asanavomereze TRT.
Kodi TRT imayendetsedwa bwanji?
Pali njira zingapo zochitira TRT. Chosankha chanu chabwino chimadalira zosowa zanu zamankhwala komanso moyo wanu. Njira zina zimafuna kuyang'anira tsiku ndi tsiku, pomwe zina zimangofunika kuti zizichitika mwezi uliwonse.
Njira za TRT zikuphatikiza:
- mankhwala akumwa
- jakisoni mnofu
- zigamba zosintha
- mafuta apakhungu
Palinso mtundu wa TRT womwe umakhudza kupaka testosterone m'kamwa mwanu kawiri tsiku lililonse.
Kodi TRT imagwiritsidwa ntchito bwanji ngati mankhwala?
TRT imagwiritsidwa ntchito mwamwambo pochiza hypogonadism, yomwe imachitika ma testes anu (omwe amatchedwanso gonads) samatulutsa testosterone yokwanira.
Pali mitundu iwiri ya hypogonadism:
- Hypogonadism yoyamba. Low T imachokera kuzinthu zokhala ndi ma gonads anu. Akupeza zikwangwani kuchokera muubongo wanu kuti apange T koma sangathe kuzipanga.
- Hypogonadism yapakati (yachiwiri). Low T amachokera ku zomwe zili mu hypothalamus kapena pituitary gland.
TRT imagwira ntchito yopangira T yomwe sikupangidwa ndi mayeso anu.
Ngati muli ndi hypogonadism yoona, TRT ikhoza:
- sinthani magwiridwe antchito anu ogonana
- onjezerani kuchuluka kwanu kwa umuna ndi voliyumu
- kuonjezera kuchuluka kwa mahomoni ena omwe amalumikizana ndi T, kuphatikiza prolactin
TRT ingathandizenso kuchepetsa milingo yachilendo ya T yomwe imayambitsidwa ndi:
- mikhalidwe yokhazikika
- Matenda amtundu
- Matenda omwe amawononga ziwalo zanu zoberekera
- machende osavomerezeka
- chithandizo cha radiation kwa khansa
- opareshoni ya ziwalo zogonana
Kodi ntchito zosagwiritsa ntchito mankhwala za TRT ndi ziti?
Mayiko ambiri, kuphatikiza United States, salola kuti anthu azigula mwalamulo ma supplements a TRT popanda mankhwala.
Komabe, anthu amafunafuna TRT pazifukwa zingapo zosakhala zachipatala, monga:
- kuonda
- kuwonjezera mphamvu zamagetsi
- kulimbikitsa kugonana kapena ntchito
- kukweza kupirira pamasewera othamanga
- kupeza minofu yowonjezera yolimbitsa thupi
TRT yasonyezedwadi kuti ili ndi zina mwazabwino. Mwachitsanzo, adaganiza kuti zidakulitsa mphamvu yamphamvu pakati pa amuna azaka zapakati komanso akulu.
Koma TRT ili ndi maubwino ochepa otsimikizika kwa anthu, makamaka anyamata achichepere, okhala ndi mulingo wabwinobwino kapena wapamwamba wa T. Ndipo zoopsa zake zitha kuposa phindu. Kafukufuku wocheperako wa 2014 adapeza kulumikizana pakati pamlingo wapamwamba wa T ndi kupanga kochepa kwa umuna.
Kuphatikiza apo, kugwiritsa ntchito TRT kuti mupeze mpikisano pamasewera kumawerengedwa kuti "kugwiritsa ntchito mankhwala osokoneza bongo" ndi mabungwe ambiri akatswiri, ndipo ambiri amaganiza kuti ndi chifukwa chothetsera masewerawa.
M'malo mwake, lingalirani kuyesa njira zina zolimbikitsira T. Nawa maupangiri asanu ndi atatu okuthandizani kuti muyambe.
Zimawononga ndalama zingati TRT?
Mtengo wa TRT umasiyana kutengera mtundu wanji womwe mwakulamulidwa. Ngati muli ndi inshuwaransi yazaumoyo ndipo mukufuna TRT kuchiza matenda anu, mwina simulipira ndalama zonse. Mtengo weniweni ukhozanso kusiyanasiyana kutengera komwe muli komanso ngati pali mtundu wa generic womwe ulipo.
Nthawi zambiri, mutha kuyembekezera kulipira kulikonse kuyambira $ 20 mpaka $ 1,000 pamwezi. Mtengo weniweni umadalira pazinthu zingapo, kuphatikiza:
- malo anu
- mtundu wa mankhwala
- njira yoyendetsera
- kaya pali generic version yomwe ilipo
Mukamaganizira za mtengo, kumbukirani kuti TRT imangolimbikitsa kuchuluka kwanu kwa T. Sichidzathetsa chifukwa chachikulu cha T yanu yotsika, chifukwa chake mungafunike chithandizo chotalikilapo.
Khalani ovomerezeka (komanso otetezeka)
Kumbukirani, ndizosaloledwa kugula T popanda mankhwala m'maiko ambiri. Mukapezeka kuti mukutero, mutha kukumana ndi mavuto azamalamulo.
Kuphatikizanso, T kugulitsidwa kunja kwa malo ogulitsa mankhwala ovomerezeka sikulamulidwa. Izi zikutanthauza kuti mutha kukhala kuti mukugula T osakaniza ndi zinthu zina zomwe sizidalembedwe. Izi zitha kukhala zowopsa kapenanso kuwopseza moyo ngati mukugwirizana ndi zina mwazomwe zimaphatikizidwazo.
Kodi pali zoopsa zilizonse zokhudzana ndi TRT?
Akatswiri akuyesetsabe kumvetsetsa zowopsa ndi zoyipa za TRT. Malinga ndi Harvard Health, maphunziro ambiri omwe adalipo kale ali ndi malire, monga kukula kocheperako kapena kugwiritsa ntchito njira zopitilira muyeso za T.
Zotsatira zake, padakali kutsutsana pazabwino komanso zowopsa zomwe zimalumikizidwa ndi TRT. Mwachitsanzo, akuti zonsezi zimawonjezera ndi kuchepetsa chiopsezo cha mitundu ina ya khansa.
A m'magazini yotchedwa Therapeutic Advances in Urology akuwonetsa kuti ena mwa malingaliro otsutsanawa ndi chifukwa chofalitsa nkhani mopitilira muyeso, makamaka ku United States.
Musanayese TRT, ndikofunikira kukhala pansi ndi omwe amakuthandizani kuti mupeze zovuta zonse zomwe zingachitike. Izi zingaphatikizepo:
- kupweteka pachifuwa
- kuvuta kupuma
- zovuta zolankhula
- kuchuluka kwa umuna
- polycythemia vera
- adatsitsa cholesterol ya HDL ("chabwino")
- matenda amtima
- kutupa m'manja kapena m'miyendo
- sitiroko
- benign prostatic hyperplasia (prostate wokulitsa)
- kugona tulo
- ziphuphu kapena zotupa zina zotere
- thrombosis yakuya kwambiri
- embolism ya m'mapapo mwanga
Simuyenera kuchita TRT ngati muli pachiwopsezo chilichonse mwazomwe zatchulidwa pamwambapa.
Mfundo yofunika
TRT yakhala njira yachithandizo kwa anthu omwe ali ndi hypogonadism kapena zomwe zimakhudzana ndi kuchepa kwa T. Koma maubwino ake kwa iwo omwe alibe vuto silimadziwika bwino, ngakhale atakhala okomeza kwambiri.
Lankhulani ndi dokotala musanamwe mankhwala amtundu uliwonse a T kapena mankhwala. Amatha kukuthandizani kudziwa ngati zolinga zanu ndi TRT ndizabwino komanso zenizeni.
Ndikofunikanso kuyang'aniridwa ndi akatswiri azachipatala mukamamwa ma T supplements kuti muzindikire zizindikiro zilizonse zosafunikira kapena zovuta zomwe zingachitike panthawi yachipatala.