Matenda achikwapu

Matenda a Whipple ndi osowa omwe amakhudza kwambiri matumbo ang'onoang'ono. Izi zimalepheretsa matumbo ang'onoang'ono kuti alole kuti michere idutse mthupi lonse. Izi zimatchedwa malabsorption.

Matenda a Whipple amayamba chifukwa cha matenda amtundu wa mabakiteriya otchedwa Tropheryma whipplei. Matendawa amakhudza amuna azungu azaka zapakati.

Matenda a Whipple ndi osowa kwambiri. Zowopsa sizikudziwika.

Zizindikiro nthawi zambiri zimayamba pang'onopang'ono. Kupweteka pamodzi ndi chizindikiro chofulumira kwambiri. Zizindikiro za matenda am'mimba (GI) zimachitika patadutsa zaka zingapo. Zizindikiro zina zitha kuphatikiza:

• Kupweteka m'mimba
• Kutsekula m'mimba
• Malungo
• Mdima wakuda m'malo owoneka bwino
  
• Ululu wophatikizana m'mapazi, mawondo, zigongono, zala, kapena madera ena
• Kutaya kukumbukira
• Kusintha kwa malingaliro
• Kuchepetsa thupi

Wothandizira zaumoyo adzayesa. Izi zitha kuwonetsa:

• Kukula kwa ma gland
• Kung'ung'uza mtima
• Kutupa m'matupi amthupi (edema)

Kuyesera kuzindikira matenda a Whipple atha kukhala:

• Kuwerengera kwathunthu kwa magazi (CBC)
• Kuyesa kwa Polymerase chain reaction (PCR) kuti muwone ngati mabakiteriya omwe amayambitsa matendawa
• Zolemba zazing'ono zazing'ono
• Pamwamba pa GI endoscopy (kuwona matumbo ndi chubu chosasunthika, chowunikira munjira yotchedwa enteroscopy)

Matendawa amathanso kusintha zotsatira za mayeso otsatirawa:

• Albumin m'magazi
• Mafuta osalumikizidwa m'mipando (mafuta achimbudzi)
• Matumbo a mtundu wa shuga (kuyamwa kwa d-xylose)

Anthu omwe ali ndi matenda a Whipple amafunika kumwa maantibayotiki kwa nthawi yayitali kuti athe kuchiza matenda aliwonse amubongo ndi dongosolo lamanjenje. Maantibayotiki otchedwa ceftriaxone amaperekedwa kudzera mumitsempha (IV). Amatsatiridwa ndi maantibayotiki ena (monga trimethoprim-sulfamethoxazole) omwe amamwa pakamwa mpaka chaka chimodzi.

Ngati zizindikiro zimabweranso pakumwa maantibayotiki, mankhwalawo amatha kusintha.

Wothandizira anu ayenera kutsatira mosamala momwe mukuyendera. Zizindikiro za matendawa zimatha kubwerera mukamaliza mankhwala. Anthu omwe akusowa chakudya chokwanira amafunikiranso kumwa zakudya zowonjezera.

Ngati sanalandire chithandizo, vutoli limakhala lakupha. Chithandizo chimachepetsa zizindikilo ndipo chitha kuchiza matendawa.

Zovuta zingaphatikizepo:

• Kuwonongeka kwa ubongo
• Kuwonongeka kwa valavu yamtima (kuchokera ku endocarditis)
• Kuperewera kwa zakudya
• Zizindikiro zimabwerera (mwina chifukwa cha kukana mankhwala)
• Kuchepetsa thupi

Itanani omwe akukuthandizani ngati muli ndi:

• Ululu wophatikizana womwe sukuchoka
• Kupweteka m'mimba
• Kutsekula m'mimba

Ngati mukuchiritsidwa matenda a Whipple, itanani omwe akukuthandizani ngati:

• Zizindikiro zimaipiraipira kapena sizikusintha
• Zizindikiro zimayambanso
• Zizindikiro zatsopano zimayamba

Matenda opatsirana m'mimba

Maiwald M, von Herbay A, Relman DA. Matenda achikwapu. Mu: Feldman M, Friedman LS, Brandt LJ, olemba. Sleisenger ndi Matenda a Mimba ndi a Fordtran Amatenda a Chiwindi. 11th ed. Philadelphia, PA: Elsevier; 2021: mutu 109.

Marth T, matenda a Schneider T. Whipple. Mu: Bennett JE, Dolin R, Blaser MJ, olemba., Eds. Mandell, Douglas, ndi Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020: mutu 210.

Kumadzulo SG. Matenda amtundu wa nyamakazi omwe amapezeka. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 259.