Matenda a Dubin-Johnson

Matenda a Dubin-Johnson (DJS) ndimatenda omwe amapitilira m'mabanja (obadwa nawo). Momwemonso, mutha kukhala ndi jaundice wofatsa pamoyo wanu wonse.

DJS ndimatenda achilendo osowa kwambiri. Kuti adzalandire vutoli, mwana ayenera kupeza mtundu wa cholakwika kuchokera kwa makolo onse awiri.

Matendawa amalepheretsa thupi kusuntha bilirubin kudzera m'chiwindi kupita mu bile. Chiwindi ndi ndulu zikawonongeka maselo ofiira ofiira, bilirubin amapangidwa. Bilirubin nthawi zambiri imalowa mu bile, yomwe imapangidwa ndi chiwindi. Kenako imadutsa mumadontho a ndulu, imadutsa ndulu, ndikulowetsa m'mimba.

Bilirubin ikapanda kunyamulidwa moyenera kupita mu ndulu, imakula m'magazi. Izi zimapangitsa khungu ndi azungu kutuwa. Izi zimatchedwa jaundice. Kuchuluka kwambiri kwa bilirubin kumatha kuwononga ubongo ndi ziwalo zina.

Anthu omwe ali ndi DJS ali ndi jaundice yofatsa yomwe ingawonjezeredwe ndi:

• Mowa
• Mapiritsi oletsa kubereka
• Zinthu zachilengedwe zomwe zimakhudza chiwindi
• Matenda
• Mimba

Jaundice wofatsa, yemwe mwina sangawonekere mpaka kutha msinkhu kapena munthu wamkulu, nthawi zambiri amakhala chizindikiro chokha cha DJS.

Mayesero otsatirawa angathandize kuzindikira matendawa:

• Chiwindi
• Magulu a enzyme ya chiwindi (kuyesa magazi)
• Seramu bilirubin
• Mitsempha ya coproporphyrin, kuphatikizapo coproporphyrin I level

Palibe chithandizo chofunikira chomwe chikufunika.

Maonekedwe ake ndiabwino kwambiri. DJS nthawi zambiri sichepetsa moyo wamunthu.

Mavuto ndi achilendo, koma atha kukhala ndi izi:

• Kupweteka m'mimba
• Jaundice kwambiri

Imbani wothandizira zaumoyo wanu ngati izi:

• Jaundice ndiwovuta
• Jaundice imakula kwambiri pakapita nthawi
• Muli ndi zowawa m'mimba kapena zizindikilo zina (zomwe zitha kukhala chizindikiro kuti matenda ena akuyambitsa matenda a jaundice)

Ngati muli ndi mbiri yabanja ya DJS, upangiri wamtundu ungakhale wothandiza ngati mukufuna kukhala ndi ana.

• Zakudya zam'mimba ziwalo

Korenblat KM, Berk PD. Yandikirani kwa wodwala yemwe ali ndi jaundice kapena mayeso osadziwika a chiwindi. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 138.

Lidofsky Sd. Jaundice. Mu: Feldman M, Friedman LS, Brandt LJ, olemba. Sleisenger ndi Matenda a Mimba ndi a Fordtran Amatenda a Chiwindi. 11th ed. Philadelphia, PA: Elsevier; 2021: mutu 21.

Roy-Chowdhury J, Roy-Chowdhury N. Bilirubin metabolism ndi zovuta zake. Mu: Sanyal AJ, Terrault N, olemba. Zakim ndi Boyer's Hepatology: Buku Lophatikiza Matenda a Chiwindi. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: chap 58.