Chiwombankhanga cha poizoni

Poizoni nodular goiter imakulitsa chithokomiro chokulitsa. Chotupacho chili ndi madera omwe akula kukula ndikupanga tinthu tating'onoting'ono. Mmodzi kapena angapo amtunduwu amatulutsa mahomoni ambiri a chithokomiro.

Poizoni nodular goiter imayamba kuchokera ku goiter yosavuta yomwe ilipo kale. Zimachitika nthawi zambiri kwa okalamba. Zowopsa zimaphatikizapo kukhala wamkazi komanso wazaka zopitilira 55. Matendawa sapezeka kawirikawiri mwa ana. Anthu ambiri omwe amakula amakhala ndi chotupa chokhala ndi tinthu tating'onoting'ono kwa zaka zambiri. Nthawi zina chithokomiro chimakula pang'ono, ndipo chotupacho sichinapezeke kale.

Nthawi zina, anthu omwe ali ndi zotupitsa zamankhwala zamankhwala zamankhwala amtundu wamadzimadzi amayamba kukhala ndi milingo yayikulu koyamba. Izi zimachitika makamaka akamamwa ayodini wambiri kudzera mumitsempha (kudzera m'mitsempha) kapena pakamwa. Ayodini atha kugwiritsidwa ntchito mosiyana ndi CT scan kapena mtima catheterization. Kutenga mankhwala omwe ali ndi ayodini, monga amiodarone, amathanso kubweretsa vutoli. Kusamuka kuchoka kudziko lomwe lili ndi vuto la ayodini kupita kudziko lokhala ndi ayodini wambiri pazakudya kungapangitsenso goiter yosavuta kukhala goiter yoopsa.

Zizindikiro zimatha kuphatikizira izi:

• Kutopa
• Kuyenda pafupipafupi
• Tsankho kutentha
• Kuchuluka chilakolako
• Kuchuluka thukuta
• Nthawi yosamba (mwa akazi)
• Kupweteka kwa minofu
• Mantha
• Kusakhazikika
• Kuchepetsa thupi

Akuluakulu amatha kukhala ndi zizindikilo zosadziwika kwenikweni. Izi zingaphatikizepo:

• Kufooka ndi kutopa
• Kupunduka ndi kupweteka pachifuwa kapena kupanikizika
• Kusintha kwa kukumbukira komanso kusinthasintha

Poizoni nodular goiter samayambitsa maso otupa omwe amatha kuchitika ndi matenda a Manda. Matenda a manda ndimatenda amthupi omwe amatsogolera ku chithokomiro chopitilira muyeso (hyperthyroidism).

Kuyezetsa thupi kumatha kuwonetsa chithokomiro chimodzi kapena zingapo. Chithokomiro chimakulitsa. Pakhoza kukhala kugunda kwamtima mwachangu kapena kunjenjemera.

Mayesero ena omwe angachitike ndi awa:

• Maselo a seramu a chithokomiro (T3, T4)
• Seramu TSH (chithokomiro cholimbikitsa timadzi)
• Kutenga chithokomiro ndikusanthula kapena kuyambitsa ayodini
• Chithokomiro ultrasound

Beta-blockers amatha kuwongolera zina mwazizindikiro za hyperthyroidism mpaka kuchuluka kwa mahomoni a chithokomiro m'thupi.

Mankhwala ena amatha kuletsa kapena kusintha momwe chithokomiro chimagwiritsira ntchito ayodini. Izi zitha kugwiritsidwa ntchito kuwongolera chithokomiro chopitilira muyeso pazinthu izi:

• Asanachite opaleshoni kapena mankhwala a radioiodine amapezeka
• Monga chithandizo chanthawi yayitali

Mankhwala a radioiodine atha kugwiritsidwa ntchito. Ayodini wa radioactive amaperekedwa pakamwa. Kenako imayang'ana mu chithokomiro chopitilira muyeso ndipo imawononga. Nthawi zambiri, kusintha kwa chithokomiro kumafunika pambuyo pake.

Kuchita opaleshoni kuchotsa chithokomiro kumatha kuchitika pamene:

• Chifuwa chachikulu kapena chotupitsa chikuyambitsa zizindikilo polemetsa kupuma kapena kumeza
• Khansara ya chithokomiro ilipo
• Chithandizo chofulumira chimafunika

Poizoni nodular goiter makamaka ndimatenda achikulire. Chifukwa chake, mavuto ena azaumoyo atha kukhudza zotsatira za izi. Munthu wachikulire amalephera kupirira matendawa pamtima. Komabe, vutoli nthawi zambiri limachiritsidwa ndi mankhwala.

Zovuta zamtima:

• Mtima kulephera
• Kugunda kwamtima kosafunikira (fibrillation yamatenda)
• Kuthamanga kwa mtima mwachangu

Zovuta zina:

• Kutaya mafupa kumabweretsa kufooka kwa mafupa

Mavuto a chithokomiro kapena namondwe akuwonjezeka kwambiri pazizindikiro za hyperthyroidism. Zitha kuchitika ndi matenda kapena kupsinjika. Mavuto a chithokomiro angayambitse:

• Kupweteka m'mimba
• Kuchepetsa chidwi chamalingaliro
• Malungo

Anthu omwe ali ndi vutoli ayenera kupita kuchipatala nthawi yomweyo.

Zovuta zakukhala ndi chotupa chachikulu kwambiri zimatha kuphatikizira kupuma movutikira kapena kumeza. Zovutazi zimachitika chifukwa cha kukakamizidwa kwa njira yapaulendo (trachea) kapena kholingo, yomwe imatsalira chithokomiro.

Itanani woyang'anira zaumoyo wanu ngati muli ndi zizindikiro za matendawa omwe atchulidwa pamwambapa. Tsatirani malangizo a omwe akukuthandizani paulendo wotsatira.

Pofuna kupewa goody nodular goiter, chitani hyperthyroidism ndi goiter yosavuta monga momwe wothandizira wanu akuwonetsera.

Poizoni multinodular khosi lotupa; Matenda a Plummer; Thyrotoxicosis - chotupa; Chithokomiro chopitilira muyeso - poyizoni chotupitsa; Hyperthyroidism - poizoni nodular goiter; Poizoni multinodular khosi lotupa; MNG

• Kukulitsa kwa chithokomiro - scintiscan
• Chithokomiro

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Jonklaas J, Cooper DS. Chithokomiro. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 213.

Kopp P. Kugwiritsa ntchito modzidzimutsa mitsempha ya chithokomiro ndi zina zomwe zimayambitsa thyrotoxicosis. Mu: Jameson JL, De Groot LJ, de Kretser DM, et al, olemba. Endocrinology: Akuluakulu ndi Ana. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier Saunders; 2016: chap 85.

Ritter JM, Flower R, Henderson G, Loke YK, MacEwan D, Rang HP. Chithokomiro. Mu: Ritter JM, Flower R, Henderson G, Loke YK, MacEwan D, Rang HP, olemba. Rang ndi Dale's Pharmacology. 9th ed. Philadelphia, PA: Elsevier; 2020: chap 35.

Smith PW, Hanks LR, Salomone LJ, Hanks JB. Chithokomiro. Mu: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Buku Lopanga Opaleshoni. Wolemba 20th. Philadelphia, PA: Elsevier; 2017: mutu 36.