Mlembi: Janice Evans
Tsiku La Chilengedwe: 25 Kulayi 2021
Sinthani Tsiku: 14 Novembala 2024
Anonim
How Sildenafil works in Erectile dysfunction?
Kanema: How Sildenafil works in Erectile dysfunction?

Zamkati

Sildenafil (Viagra) amagwiritsidwa ntchito pochiza kuwonongeka kwa erectile (kusowa mphamvu; kulephera kupeza kapena kusunga erection) mwa amuna. Sildenafil (Revatio) imagwiritsidwa ntchito kupititsa patsogolo kuthekera kochita masewera olimbitsa thupi mwa achikulire omwe ali ndi matenda oopsa (pulmonary arterial hypertension) (PAH; kuthamanga kwa magazi m'mitsuko yonyamula magazi kumapapu, ndikupangitsa kupuma pang'ono, chizungulire, ndi kutopa). Ana sayenera kumwa sildenafil, koma nthawi zina, dokotala amatha kusankha kuti sildenafil (Revatio) ndiye mankhwala abwino kwambiri ochizira matenda amwana. Sildenafil ali mgulu la mankhwala otchedwa phosphodiesterase (PDE) inhibitors. Sildenafil amathetsa kukanika kwa erectile powonjezera magazi kupita ku mbolo panthawi yogonana. Kuwonjezeka kwa magazi kumatha kuyambitsa erection. Sildenafil amathandizira PAH pochepetsa mitsempha yamagazi m'mapapu kuti magazi aziyenda mosavuta.

Ngati mukumwa sildenafil kuti muthane ndi vuto la erectile, muyenera kudziwa kuti silichiza kuwonongeka kwa erectile kapena kukulitsa chilakolako chogonana. Sildenafil sateteza mimba kapena kufalikira kwa matenda opatsirana pogonana monga kachilombo ka HIV.


Sildenafil amabwera ngati piritsi ndikuyimitsidwa (madzi; Revatio kokha) kuti atenge pakamwa.

Ngati mukumwa sildenafil kuti muzitha kuthana ndi vuto la erectile, tsatirani malangizo a dokotala ndi malangizo omwe ali m'ndimeyi. Tengani sildenafil ngati mukufunikira musanachite zogonana. Nthawi yabwino kutenga sildenafil ndi pafupifupi ola limodzi musanachite zogonana, koma mutha kumwa mankhwala nthawi iliyonse kuyambira maola 4 mpaka mphindi 30 musanachite zogonana. Sildenafil nthawi zambiri sayenera kumwedwa kangapo maola 24 aliwonse. Ngati muli ndi thanzi linalake kapena mukumwa mankhwala ena, dokotala angakuuzeni kuti mutenge sildenafil pafupipafupi. Mutha kutenga sildenafil kapena wopanda chakudya. Komabe, ngati mutenga sildenafil ndi chakudya chamafuta ambiri, zimatenga nthawi kuti mankhwala ayambe kugwira ntchito.

Ngati mukumwa sildenafil kuchiza PAH, tsatirani malangizo a dokotala ndi malangizo omwe ali m'ndimeyi. Mutha kutenga sildenafil katatu patsiku kapena wopanda chakudya. Tengani sildenafil mozungulira nthawi yofananira tsiku lililonse, ndipo ikani mlingo wanu pafupifupi 4 mpaka 6 maola kupatukana.


Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani sildenafil monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Sambani madzi bwino kwa masekondi 10 musanagwiritse ntchito kusakaniza mankhwala mofanana. Gwiritsani ntchito syringe yapakamwa yoperekedwa ndi mankhwala anu kuti muyese ndikumwa mlingo wanu. Tsatirani malangizo a wopanga kuti mugwiritse ntchito ndikuyeretsa jakisoni wam'kamwa. Osasakaniza madziwo ndi mankhwala ena kapena onjezerani chilichonse kuti chikometsedwe cha mankhwalawo.

Ngati mukumwa sildenafil chifukwa cha kulephera kwa erectile, dokotala wanu mwina angakuyambitseni muyeso wa sildenafil ndikuwonjezera kapena kuchepa mlingo wanu kutengera momwe mumayankhira mankhwala. Uzani dokotala wanu ngati sildenafil sakugwira ntchito bwino kapena ngati mukukumana ndi zovuta zina.

Ngati mukutenga sildenafil ya PAH, muyenera kudziwa kuti sildenafil imayang'anira PAH koma siyichiritsa. Pitilizani kutenga sildenafil ngakhale mukumva bwino. Osasiya kumwa sildenafil osalankhula ndi dokotala.


Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa nthawi zina amapatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge sildenafil,

  • uzani dokotala ndi wamankhwala ngati simukugwirizana ndi sildenafil, mankhwala aliwonse, kapena chilichonse mwazinthu zopangidwa ndi sildenafil. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • musatenge sildenafil ngati mukumwa kapena mwatenga kumene riociguat (Adempas) kapena nitrate (mankhwala opweteka pachifuwa) monga isosorbide dinitrate (Isordil), isosorbide mononitrate (Monoket), ndi nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat , ena). Nitrate amabwera ngati mapiritsi, timapepala tating'ono (pansi pa lilime) mapiritsi, opopera, zigamba, pastes, ndi mafuta. Funsani dokotala ngati simukudziwa ngati mankhwala anu ali ndi nitrate.
  • musatenge mankhwala am'misewu okhala ndi nitrate monga amyl nitrate ndi butyl nitrate ('poppers') mukamamwa sildenafil.
  • Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: alpha blockers monga alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax, ku Jalyn), ndi terazosin; amlodipine (Norvasc, ku Amturnide, ku Tekamlo); ma antifungal ena monga itraconazole (Onmel, Sporanox) ndi ketoconazole (Nizoral); maanticoagulants ('oonda magazi') monga warfarin (Coumadin, Jantoven); barbiturates ena monga butalbital (ku Butapap, ku Fioricet, ku Fiorinal, ena) ndi secobarbital (Seconal); zotchinga beta monga atenolol (Tenormin, mu Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, ku Dutoprol), nadolol (Corgard, ku Corzide), ndi propranolol (Hemangeol, Inderal LA, InnoPran); chifuwa (Tracleer); cimetidine; efavirenz (Sustiva, ku Atripla); erythromycin (EES, E-Mycin, Erythrocin); HIV protease inhibitors kuphatikiza amprenavir (Agenerase; sikupezeka ku US), atazanavir (Reyataz, ku Evotaz), darunavir (Prezista, ku Prezcobix), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (ku Kaletra), nelfinavir Viracept), ritonavir (Norvir, ku Kaletra), saquinavir (Invirase), ndi tipranavir (Aptivus); nevirapine (Viramune); mankhwala ena kapena zida zochizira kukanika kwa erectile; mankhwala othamanga magazi; mankhwala ena okomoka kuphatikiza carbamazepine (Carbatrol, Epitol, Tegretol, ena), phenobarbital, ndi phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); ndi rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.Mankhwala ena ambiri amathanso kulumikizana ndi sildenafil, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
  • uzani dokotala wanu za mankhwala azitsamba omwe mukumwa kapena mukukonzekera, makamaka wort ya St.
  • uzani dokotala wanu ngati mumasuta, ngati mudakhalapo ndi erection yomwe idatenga maola angapo, ndipo ngati mwangotaya madzi ambiri amthupi (kusowa madzi m'thupi). Izi zitha kuchitika ngati mukudwala malungo, kutsegula m'mimba, kapena kusanza; thukuta kwambiri; kapena osamwa zakumwa zokwanira. Uzani dokotala wanu ngati mwakhalapo kapena munakhalapo ndi matenda am'mapapo (venous-occlusive) (PVOD; kutsekeka kwa mitsempha m'mapapu); zilonda zam'mimba; mtima, impso, kapena matenda a chiwindi; matenda a mtima; kugunda kwamtima kosasintha; sitiroko; kupweteka pachifuwa; kuthamanga kapena kuthamanga kwa magazi; cholesterol; kusokonezeka kwa magazi; mavuto azungulira magazi; mavuto am'magazi am'magazi monga sickle cell anemia (matenda am'magazi ofiira), multipleeloma (khansa yamagazi), kapena leukemia (khansa yamagazi oyera); zikhalidwe zomwe zimakhudza mawonekedwe a mbolo (mwachitsanzo, angulation, cavernosal fibrosis, kapena matenda a Peyronie); kapena matenda ashuga. Muuzeni dokotala wanu ngati inu kapena abale anu muli ndi matenda amaso monga retinitis pigmentosa (vuto lobadwa nalo lomwe limapangitsa kuti musamaone) kapena ngati mwakhala mukuwonongeka mwadzidzidzi, makamaka mutakhala adauza kuti kutayika kwamasomphenya kudachitika chifukwa cha kutsekeka kwa magazi kumitsempha yomwe imakuthandizani kuwona.
  • ngati ndinu mayi ndipo mukumwa sildenafil kuchiza PAH, auzeni dokotala ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukamamwa sildenafil, itanani dokotala wanu.
  • ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa sildenafil.
  • ngati mukumwa sildenafil kuti muzitha kuthana ndi vuto la erectile, auzeni dokotala ngati mwalangizidwapo ndi akatswiri azaumoyo kuti mupewe kugonana pazifukwa zamankhwala kapena ngati munamvapo kupweteka pachifuwa panthawi yogonana. Kugonana kumatha kukhala kovuta mumtima mwanu, makamaka ngati muli ndi matenda amtima. Ngati mukumva kupweteka pachifuwa, chizungulire, kapena mseru panthawi yogonana, itanani dokotala wanu nthawi yomweyo ndikupewa kuchita zogonana mpaka dokotala atakuwuzani zina.
  • auzeni onse omwe amakupatsani zaumoyo kuti mukutenga sildenafil. Ngati mungafunike chithandizo chodzidzimutsa pamavuto amtima, omwe amakuthandizani amafunika kudziwa kuti mwamaliza liti kutenga sildenafil.

Lankhulani ndi dokotala wanu za kudya mphesa ndi kumwa madzi amphesa mukamamwa mankhwalawa.

Ngati mukumwa sildenafil chifukwa cha kutayika kwa erectile, ndiye kuti simungaphonye mlingo chifukwa mankhwalawa amatengedwa ngati mukufunikira, osati pamlingo wokhazikika.

Ngati mukumwa sildenafil ya PAH, tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Sildenafil imatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • mutu
  • kutentha pa chifuwa
  • kutsegula m'mimba
  • kutentha (kumva kutentha)
  • mwazi wa m'mphuno
  • kuvuta kugona kapena kugona
  • dzanzi, kutentha, kapena kumva kulasalasa mmanja, manja, mapazi, kapena miyendo
  • kupweteka kwa minofu
  • kusintha kwamasomphenya amtundu (kuwona mtundu wabuluu pazinthu kapena kukhala kovuta kusiyanitsa buluu ndi wobiriwira)
  • kutengeka ndi kuwala

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:

  • kutaya mwadzidzidzi masomphenya (onani pansipa kuti mumve zambiri)
  • kusawona bwino
  • kuchepa kwadzidzidzi kapena kutaya kumva
  • kulira m'makutu
  • chizungulire kapena mutu wopepuka
  • kukomoka
  • kupweteka pachifuwa
  • kukulitsa kupuma pang'ono
  • erection yomwe imapweteka kapena imatenga nthawi yayitali kuposa maola 4
  • kuyabwa kapena kutentha pamene mukukodza
  • zidzolo

Odwala ena amataya mwadzidzidzi ena mwa iwo kapena masomphenya onse atamwa sildenafil kapena mankhwala ena ofanana ndi sildenafil. Kutaya masomphenya kumakhala kosatha nthawi zina. Sizikudziwika ngati kutayika kwamasomphenya kudachitika ndi mankhwala. Ngati mukuwonongeka mwadzidzidzi pomwe mukumwa sildenafil, itanani dokotala wanu mwachangu. Musathenso kumwa sildenafil kapena mankhwala ofanana ndi awa monga tadalafil (Cialis) kapena vardenafil (Levitra) mpaka mutalankhula ndi dokotala.

Pakhala pali malipoti okhudza kuwonongeka kwa mtima, kupwetekedwa mtima, kugunda kwamtima mosasinthasintha, kutuluka magazi muubongo kapena m'mapapu, kuthamanga kwa magazi, komanso kufa mwadzidzidzi mwa amuna omwe adatenga sildenafil chifukwa cha kuwonongeka kwa erectile. Ambiri, koma osati onse, mwa anthuwa anali ndi mavuto amtima asanatenge sildenafil. Sizikudziwika ngati izi zidachitika chifukwa cha sildenafil, zochitika zogonana, matenda amtima, kapena kuphatikiza izi ndi zina. Lankhulani ndi dokotala wanu za kuopsa kotenga sildenafil.

Odwala ena adachepetsa mwadzidzidzi kapena kutaya kumva atalandira sildenafil kapena mankhwala ena ofanana ndi sildenafil. Kutaya kwakumva nthawi zambiri kumangokhala ndi khutu limodzi lokha ndipo sizimasintha nthawi zonse mankhwalawo akaimitsidwa. Sizikudziwika ngati vuto lakumva lidayamba chifukwa cha mankhwalawo. Ngati mukumva mwadzidzidzi, nthawi zina ndikulira m'makutu kapena chizungulire, mukamamwa sildenafil, itanani dokotala wanu mwachangu. Ngati mukumwa sildenafil (Viagra) ya vuto la erectile, musathenso kumwa sildenafil (Viagra) kapena mankhwala ofanana ndi amenewa monga tadalafil (Cialis) kapena vardenafil (Levitra) mpaka mutalankhula ndi dokotala wanu. Ngati mukumwa sildenafil (Revatio) ya PAH, musaleke kumwa mankhwala anu mpaka mutalankhula ndi dokotala wanu.

Sildenafil ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani mapiritsi kutentha kwa firiji komanso kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Sungani kuyimitsidwa kutentha kapena firiji, koma osaziziritsa. Chotsani kuyimitsidwa kulikonse komwe sikugwiritsidwe ntchito pakatha masiku 60.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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