Lactic acidosis

Lactic acidosis amatanthauza lactic acid yomwe imamangidwa m'magazi. Lactic acid imapangidwa pakakhala mpweya wa oxygen, umakhala wotsika m'maselo amkati mwa thupi komwe kagayidwe kamachitika.

Chifukwa chofala kwambiri cha lactic acidosis ndimatenda akulu azachipatala omwe kuthamanga kwa magazi kumakhala kotsika komanso mpweya wochepa kwambiri umafika pamatupi amthupi. Kuchita masewera olimbitsa thupi mwamphamvu kapena kugwedezeka kungayambitse lactic acidosis kwakanthawi. Matenda ena amathanso kuyambitsa vutoli kuphatikiza:

• Edzi
• Kuledzera
• Khansa
• Matenda a chiwindi
• Poizoni wa cyyanide
• Impso kulephera
• Kulephera kupuma
• Sepsis (matenda akulu)

Mankhwala ena sangayambitse lactic acidosis:

• Ena mwa inhalers ankachiza mphumu kapena COPD
• Epinephrine
• Mankhwala otchedwa linezolid
• Metformin, yomwe imagwiritsidwa ntchito pochiza matenda ashuga (nthawi zambiri ikamalowetsedwa)
• Mtundu umodzi wa mankhwala omwe amagwiritsidwa ntchito pochiza kachilombo ka HIV
• Malangizo

Zizindikiro zimaphatikizapo:

• Nseru
• Kusanza
• Kufooka

Mayeso atha kuphatikizira kuyesa magazi kuti muwone kuchuluka kwa lactate ndi electrolyte.

Chithandizo chachikulu cha lactic acidosis ndikuthetsa vuto lazachipatala lomwe limayambitsa vutoli.

Palmer BF. Matenda a acidosis. Mu: Feehally J, Floege J, Tonelli, Johnson RJ, olemba. Chachikulu Chachipatala Nephrology. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier; 2019: chaputala 12.

Seifter JL. Mavuto amadzimadzi. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. Wolemba 25. Philadelphia, PA: Elsevier Saunders; 2016: mutu 118.

Wopopera RJ. Mavuto amadzimadzi. Mu: Makoma RM, Hockberger RS, Gausche-Hill M, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier Saunders; 2018: chap 116.