Chotupa cha Leydig testicular

Chotupa cha khungu la Leydig ndi chotupa cha machende. Amayamba kuchokera ku maselo a Leydig. Awa ndi ma cell am'matumbo omwe amatulutsa mahomoni amphongo, testosterone.

Zomwe zimayambitsa chotupa sizikudziwika. Palibe zifukwa zomwe zimadziwika pachiwopsezo cha chotupachi. Mosiyana ndi zotupa zamagulu anyongolotsi za machende, chotupacho sichikuwoneka kuti chikugwirizana ndi mayeso osavomerezeka.

Zotupa zama cell a Leydig zimapanga ziwerengero zochepa kwambiri zamatenda a testicular. Amapezeka nthawi zambiri mwa amuna azaka zapakati pa 30 ndi 60. Chotupachi sichimapezeka mwa ana asanakule msinkhu, koma chimatha kutha msinkhu.

Sipangakhale zizindikiro.

Zizindikiro zikachitika, zimatha kuphatikiza:

• Kusamva bwino kapena kupweteka kwa machende
• Kukulitsa kwa machende kapena kusintha momwe akumvera
• Kukula kwakukulu kwa minofu ya m'mawere (gynecomastia) - komabe, izi zimatha kuchitika mwa anyamata omwe alibe khansa ya testicular
• Kulemera kwachitsulo
• Mphuno kapena kutupa machende onse
• Ululu m'mimba kapena kumbuyo
• Osakhoza kukhala ndi ana (kusabereka)

Zizindikiro m'mbali zina za thupi, monga mapapu, pamimba, m'chiuno, kumbuyo, kapena muubongo zimatha kuchitika ngati khansara yafalikira.

Kuyesedwa kwakuthupi kumawulula chotupa cholimba m'modzi mwa machende. Wothandizira zaumoyo akatenga tochi mpaka pamatumbo, nyali sikudutsa pamtambo. Kuyeza kumeneku kumatchedwa transillumination.

Mayesero ena ndi awa:

• Kuyesa magazi pazotupa: alpha fetoprotein (AFP), chorionic gonadotropin (beta HCG), ndi lactate dehydrogenase (LDH)
• Kuyeza kwa CT pachifuwa, pamimba ndi m'chiuno kuti muwone ngati khansara yafalikira
• Ultrasound ya scrotum

Kupenda minofu kumachitika pambuyo poti machende onse achotsedwa opaleshoni (orchiectomy).

Chithandizo cha chotupa cha khungu la Leydig chimadalira gawo lake.

• Khansara ya Gawo I silinafalikire kupitirira machende.
• Khansara yachiwiri yafalikira kumatenda am'mimba m'mimba.
• Khansa ya Gawo lachitatu yafalikira kupitilira ma lymph node (mwina mpaka chiwindi, mapapo, kapena ubongo).

Opaleshoni yachitika kuti muchotse machende (orchiectomy). Ma lymph node apafupi amathanso kuchotsedwa (lymphadenectomy).

Chemotherapy itha kugwiritsidwa ntchito pochiza chotupacho. Popeza zotupa za Leydig sizichitikachitika, mankhwalawa sanaphunzirepo mochuluka ngati mankhwala a khansa ina yamatenda ofala kwambiri.

Kuyanjana ndi gulu lothandizira momwe mamembala amagawana zomwe amakumana nazo ndimavuto nthawi zambiri kumathandizira kuchepetsa nkhawa zamatenda.

Khansa ya testicular ndi imodzi mwa khansa yochiritsidwa komanso yochiritsidwa. Chiyembekezo chimakhala choyipa ngati chotupacho sichipezeka msanga.

Khansara imatha kufalikira mbali zina za thupi. Masamba omwe amapezeka kwambiri ndi awa:

• Mimba
• Mapapo
• Dera la Retroperitoneal (dera lomwe lili pafupi ndi impso kuseri kwa ziwalo zina m'mimba)
• Mphepete

Zovuta za opaleshoni zitha kukhala:

• Magazi ndi matenda
• Kusabereka (ngati machende onse atachotsedwa)

Ngati ndinu a msinkhu wobereka, funsani omwe akukuthandizani za njira zosungira umuna wanu kuti mugwiritse ntchito mtsogolo.

Itanani omwe akukuthandizani ngati muli ndi zizindikiro za khansa ya testicular.

Kuyeserera mayeso a testicular (TSE) mwezi uliwonse kumatha kuthandiza kuzindikira khansa ya testicular koyambirira, isanafike. Kupeza khansa ya testicular koyambirira ndikofunikira kuti muthandizidwe bwino ndikupulumuka.

Chotupa - khungu la Leydig; Chotupa cha testicular - Leydig

• Kutengera kwamwamuna kubereka

Friedlander TW, Khansa yaying'ono ya E. Testicular. Mu: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, olemba. Chipatala cha Abeloff's Oncology. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier; 2020: chap 83.

Tsamba la National Cancer Institute. Chithandizo cha khansa ya testicular (PDQ) - mtundu wa akatswiri azaumoyo. www.cancer.gov/types/testicular/hp/chithandizo-chithandizo-chipatala-pdq. Idasinthidwa pa Meyi 21, 2020. Idapezeka pa Julayi 21, 2020.

Stephenson AJ, Gilligan TD. Mitsempha ya testis. Mu: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, olemba. Campbell-Walsh-Wein Urology. Wolemba 12. Philadelphia, PA: Elsevier; 2021: mutu 76.