Matenda a Psoriatic

Matenda a Psoriatic ndimavuto olumikizana (nyamakazi) omwe nthawi zambiri amapezeka ndimatenda akhungu otchedwa psoriasis.

Psoriasis ndimavuto akhungu omwe amayambitsa zigamba zofiira pakhungu. Ndiwowopsa (wosakhalitsa) wotupa. Matenda a Psoriatic amapezeka pafupifupi 7% mpaka 42% ya anthu omwe ali ndi psoriasis. Nail psoriasis yolumikizidwa ndi psoriatic nyamakazi.

Nthawi zambiri, psoriasis imabwera asanafike nyamakazi. Mwa anthu ochepa, nyamakazi imabwera matendawa asanachitike. Komabe, kukhala ndi psoriasis yolimba, yofalikira kumawoneka kuti kumawonjezera mwayi wopeza nyamakazi ya psoriatic.

Zomwe zimayambitsa matenda a nyamakazi sizidziwika. Chibadwa, chitetezo chamthupi, komanso chilengedwe zimatha kuthandizira. Zikuwoneka kuti matenda akhungu ndi olumikizana atha kukhala ndi zifukwa zomwezi. Komabe, sizingachitike limodzi.

Nyamakazi imatha kukhala yofatsa ndipo imangokhala ndi ziwalo zochepa chabe. Malumikizano kumapeto kwa zala kapena zala zakumaso atha kukhudzidwa kwambiri. Matenda a Psoriatic nthawi zambiri samakhala ofanana kuchititsa nyamakazi mbali imodzi ya thupi.

Kwa anthu ena, matendawa amatha kukhala owopsa ndipo amakhudza ziwalo zambiri, kuphatikizapo msana. Zizindikiro mu msana zimaphatikizapo kuuma ndi kupweteka. Nthawi zambiri zimachitika m'munsi mwa msana ndi sacrum.

Anthu ena omwe ali ndi nyamakazi ya psoriatic amatha kutupa m'maso.

Nthawi zambiri, anthu omwe ali ndi nyamakazi ya psoriatic amakhala ndi kusintha kwa khungu ndi msomali wa psoriasis. Nthawi zambiri khungu limakula nthawi imodzi ndi nyamakazi.

Matenda amatha kutentha ndi nyamakazi ya psoriatic. Zitsanzo ndi monga Achilles tendon, plantar fascia, ndi tendon sheath yomwe ili m'manja.

Mukayezetsa thupi, wothandizira zaumoyo adzafuna:

• Kutupa pamodzi
• Zikopa za khungu (psoriasis) ndi kukhazikika m'misomali
• Chifundo
• Kutupa m'maso

Ma x-ray ophatikizana atha kuchitidwa.

Palibe mayesero amtundu wa magazi a psoriatic arthritis kapena psoriasis. Kuyesa kuthana ndi mitundu ina ya nyamakazi kumatha kuchitika:

• Chifuwa cha nyamakazi
• Ma anti-CCP antibodies

Wothandizirayo akhoza kuyesa mtundu wina wotchedwa HLA-B27 Anthu omwe akutenga nawo mbali kumbuyo amakhala ndi HLA-B27.

Wothandizira anu amatha kupereka mankhwala osagwiritsa ntchito ma antisteroidal (NSAIDs) kuti achepetse kupweteka komanso kutupa kwamafundo.

Matenda a nyamakazi omwe samayenda bwino ndi ma NSAID adzafunika kuthandizidwa ndi mankhwala omwe amatchedwa anti -heutatic antirheumatic drug (DMARDs). Izi zikuphatikiza:

• Methotrexate
• Leflunomide
• Sulfasalazine

Apremilast ndi mankhwala ena omwe amagwiritsidwa ntchito pochizira nyamakazi ya psoriatic.

Mankhwala atsopano a biologic ndi othandiza pa matenda a psoriatic arthritis omwe samayang'aniridwa ndi DMARD. Mankhwalawa amatseka puloteni yotchedwa tumor necrosis factor (TNF). Nthawi zambiri amathandiza pa matenda a khungu komanso matenda olumikizana ndi nyamakazi ya psoriatic. Mankhwalawa amaperekedwa ndi jakisoni.

Mankhwala ena atsopano a biologic amapezeka kuti athe kuchiza nyamakazi ya psoriatic yomwe ikupitilira ngakhale pogwiritsa ntchito ma DMARD kapena othandizira anti-TNF. Mankhwalawa amaperekedwanso ndi jakisoni.

Malo opweteka kwambiri amatha kuchiritsidwa ndi jakisoni wa steroid. Izi zimagwiritsidwa ntchito pokhapokha gawo limodzi kapena angapo ataphatikizidwa. Akatswiri ambiri samalimbikitsa corticosteroids yamlomo yamatenda a psoriatic. Kugwiritsa ntchito kwawo kumatha kukulitsa psoriasis ndikusokoneza zotsatira za mankhwala ena.

Nthawi zambiri, pamafunika kuchitidwa opaleshoni kuti akonze kapena m'malo am'malo owonongeka.

Anthu omwe ali ndi kutupa kwa diso ayenera kuwona katswiri wa maso.

Wothandizira anu atha kupereka lingaliro la kupumula ndi kuchita masewera olimbitsa thupi. Thandizo lakuthupi lingathandize kukulitsa mayendedwe olumikizana. Muthanso kugwiritsa ntchito mankhwala ozizira kutentha ndi kuzizira.

Matendawa nthawi zina amakhala ofatsa ndipo amakhudza malo ochepa okha. Komabe, mwa anthu ambiri omwe ali ndi vuto la nyamakazi ya psoriatic m'malo olumikizirana mafupa amapezeka mkati mwa zaka zingapo zoyambirira. Kwa anthu ena, nyamakazi yoyipa kwambiri imatha kupundula m'manja, kumapazi, ndi msana.

Anthu ambiri omwe ali ndi nyamakazi ya psoriatic omwe samasintha ndi ma NSAID ayenera kuwona rheumatologist, katswiri wamatenda am'mimba, komanso dermatologist wa psoriasis.

Kuchiritsidwa koyambirira kumachepetsa kupweteka ndikupewa kuwonongeka kwamagulu, ngakhale atakhala ovuta kwambiri.

Itanani omwe akukuthandizani ngati mukudwala matenda a nyamakazi komanso psoriasis.

Nyamakazi - psoriatic; Psoriasis - nyamakazi ya psoriatic; Spondyloarthritis - nyamakazi ya psoriatic; Zamgululi

• Psoriasis - guttate pamanja ndi pachifuwa
• Psoriasis - guttate patsaya

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Gladman D, Rigby W, Azevedo VF, ndi al. Tofacitinib yamatenda a psoriatic mwa odwala omwe sangakwanitse kuyankha ma TNF inhibitors. N Engl J Med. 2017; 377:1525-1536.

Achinyamata JS, Schöls M, Braun J, et al. Kuchiza axial spondyloarthritis ndi zotumphukira spondyloarthritis, makamaka psoriatic nyamakazi, kulunjika: 2017 kusinthidwa kwa malingaliro ndi gulu lapadziko lonse lapansi. Ann Rheum Dis. 2018; 77 (1): 3-17. (Adasankhidwa) PMID: 28684559 pubmed.ncbi.nlm.nih.gov/28684559/.

Veale DJ, Orr C. Kuwongolera nyamakazi ya psoriatic. Mu: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, olemba. Zamatsenga. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2019: chap 131.