Kashiamu pyrophosphate nyamakazi

Matenda a nyamakazi a calcium pyrophosphate dihydrate (CPPD) ndi matenda olumikizana omwe amatha kuyambitsa nyamakazi. Monga gout, makhiristo amapangika m'malo olumikizirana mafupa. Koma mu nyamakazi iyi, makhiristo sanapangidwe kuchokera ku uric acid.

Kukhazikika kwa calcium pyrophosphate dihydrate (CPPD) kumayambitsa matendawa. Kuchulukana kwa mankhwalawa kumapanga timibulu m'matumba a mafupa. Izi zimabweretsa ziwopsezo zotupa palimodzi ndi kupweteka m'mabondo, pamikono, m'mapiko, m'mapewa ndi mafupa ena. Mosiyana ndi gout, cholumikizira metatarsal-phalangeal chala chakuphazi sichimakhudzidwa.

Pakati pa okalamba, CPPD ndi yomwe imayambitsa matenda a nyamakazi mwadzidzidzi. Kuukira kumayambitsidwa ndi:

• Kuvulaza olowa
• Hyaluronate jekeseni olowa
• Matenda azachipatala

Matenda a CPPD amakhudza kwambiri okalamba chifukwa kufooka kwa mafupa ndi mafupa am'mimba kumawonjezeka ndi ukalamba. Kuwonongeka kwamagulu kotereku kumawonjezera chizolowezi chofunsira kwa CPPD. Komabe, nyamakazi ya CPPD nthawi zina imatha kukhudza achinyamata omwe ali ndi zovuta monga:

• Chidziwitso
• Matenda a Parathyroid
• Kulephera kwa impso kwa Dialysis

Nthawi zambiri, nyamakazi ya CPPD siyimayambitsa zizindikiro zilizonse. M'malo mwake, ma x-ray a mafupa omwe akhudzidwa monga mawondo amawonetsera calcium.

Anthu ena omwe amakhala ndi CPPD osachiritsika m'malo am'magulu akuluakulu amatha kukhala ndi izi:

• Ululu
• Kutupa
• Kutentha
• Kufiira

Kuukira kwa ululu wamagulu kumatha miyezi. Pakhoza kukhala palibe zizindikilo pakati pakuukiridwa.

Mwa anthu ena nyamakazi ya CPPD imawononga kwambiri cholumikizira.

Matenda a nyamakazi a CPPD amathanso kupezeka mumsana, m'munsi komanso kumtunda. Kupanikizika kwa mitsempha ya msana kungayambitse kupweteka m'manja kapena miyendo.

Chifukwa zizindikirozo ndizofanana, nyamakazi ya CPPD imatha kusokonezedwa ndi:

• Matenda a nyamakazi (gout)
• Nyamakazi
• Matenda a nyamakazi

Matenda ambiri am'mimba amawonetsa zofananira. Kuyesa mosamala madzimadzi olumikizana ndi makhiristo kungathandize adotolo kuzindikira vutoli.

Mutha kuyesa izi:

• Kuyesa kwamadzimadzi kofanana kuti mupeze ma cell oyera ndi calcium calcium pyrophosphate
• Ma x-ray ophatikizana kuti ayang'ane kuwonongeka kwamalumikizidwe ndi ma calcium calcium m'malo ophatikizana
• Mayesero ena olumikizana nawo monga CT scan, MRI kapena ultrasound, ngati angafunike
• Kuyezetsa magazi kuti muwone ngati zinthu zikugwirizana ndi calcium pyrophosphate arthritis

Chithandizo chitha kuphatikizira kuchotsa madzimadzi kuti muchepetse kuphatikizika. Singano imayikidwa mu cholumikizira ndipo madzi amatuluka. Njira zina zodziwika bwino zochizira ndi izi:

• Majakisoni a Steroid: kuchiza malo otupa kwambiri
• Oral steroids: kuchiza malo angapo otupa
• Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs): kuchepetsa ululu
• Colchicine: kuchiza matenda a nyamakazi ya CPPD
• Kwa matenda a nyamakazi a CPPD m'mapazi angapo a methotrexate kapena hydroxychloroquine atha kukhala othandiza

Anthu ambiri amachita bwino ndi mankhwala kuti achepetse kupweteka kwakanthawi. Mankhwala monga colchicine amatha kuthandiza kupewa kubwereza kubwereza. Palibe mankhwala ochotsera makhiristo a CPPD.

Kuwonongeka kwakanthawi kwamalumikizidwe kumatha kuchitika popanda chithandizo.

Itanani yemwe amakuthandizani ngati akukumana ndi zotupa zotupa palimodzi.

Palibe njira yodziwika yothetsera vutoli. Komabe, kuthana ndi mavuto ena omwe angayambitse matenda a nyamakazi a CPPD atha kupangitsa kuti vutoli lisakule kwambiri.

Maulendo obwereza pafupipafupi amatha kuthandiza kuti ziwalo zomwe zakhudzidwa zisawonongeke mpaka kalekale.

Kashiamu pyrophosphate dihydrate mafunsidwe matenda; Matenda a CPPD; Matenda achilengedwe a CPPD; Zolemba; Pyrophosphate nyamakazi; Chondrocalcinosis

• Kutupa kolumikizana kwamapewa
• Nyamakazi
• Kapangidwe ka cholumikizira

Andrés M, Sivera F, Pascual E. Therapy wa CPPD: zosankha ndi umboni. Wotsutsa Rheumatol Rep. 2018; 20 (6): 31. PMID: 29675606 pubed.ncbi.nlm.nih.gov/29675606/.

Edwards NL. Matenda a Crystal. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 257.

Terkeltaub R. Matenda a kristalo a calcium: calcium pyrophosphate dihydrate komanso calcium calcium phosphate. Mu: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, olemba. Kelley ndi Firestein's Bookbook of Rheumatology. 10th ed. Philadelphia, PA: Elsevier; 2017: mutu 96.