IgA vasculitis - Henoch-Schönlein purpura

IgA vasculitis ndi matenda omwe amaphatikizapo mawanga ofiira pakhungu, kupweteka pamfundo, mavuto am'mimba, ndi glomerulonephritis (mtundu wamatenda a impso). Amadziwikanso kuti Henoch-Schönlein purpura (HSP).

IgA vasculitis imayambitsidwa ndi kuyankha kwachilendo kwa chitetezo chamthupi. Zotsatira zake ndikutupa m'mitsempha yamagazi yaying'ono pakhungu. Mitsempha yamagazi m'malo olumikizirana mafupa, impso, kapena matumbo imathanso kukhudzidwa. Sizikudziwika bwino chifukwa chake izi zimachitika.

Matendawa amawonekera kwambiri mwa ana azaka zapakati pa 3 ndi 15, koma amatha kuwoneka achikulire. Amakonda kwambiri anyamata kuposa atsikana. Anthu ambiri omwe amadwala matendawa anali ndi matenda opatsirana apamwamba m'masabata apitawo.

Zizindikiro ndi mawonekedwe a IgA vasculitis atha kuphatikiza:

• Mawanga ofiira pakhungu (purpura). Izi zimachitika pafupifupi pafupifupi ana onse omwe ali ndi vutoli. Izi zimachitika kwambiri pamwamba pa matako, miyendo yakumunsi, ndi zigongono.
• Kupweteka m'mimba.
• Ululu wophatikizana.
• Mkodzo wosazolowereka (mwina sangakhale ndi zisonyezo).
• Kutsekula m'mimba, nthawi zina kumakhala magazi.
• Ming'oma kapena angioedema.
• Nseru ndi kusanza.
• Kutupa ndi kupweteka kwa khungu la anyamata.
• Mutu.

Wothandizira zaumoyo adzayang'ana thupi lanu ndikuyang'ana khungu lanu. Kuyezetsa thupi kudzawonetsa zilonda zakhungu (purpura, zotupa) komanso kufatsa molumikizana.

Mayeso atha kuphatikiza:

• Kuwunika kumachitika nthawi zonse.
• Kuwerengera kwathunthu kwa magazi. Mwaziwo ukhoza kukhala wabwinobwino.
• Mayeso a coagulation: izi ziyenera kukhala zabwinobwino.
• Khungu lachikopa, makamaka kwa akulu.
• Kuyezetsa magazi kuti ayang'ane zifukwa zina zotupa m'mitsempha yamagazi, monga systemic lupus erythematosus, ANCA-associated vasculitis kapena hepatitis.
• Kwa achikulire, kuyesa kwa impso kuyenera kuchitidwa.
• Kuyerekeza kuyesa pamimba ngati kupweteka kulipo.

Palibe mankhwala enieni. Milandu yambiri imatha yokha. Kupweteka kwapakati kumatha kusintha ndi ma NSAID monga naproxen. Ngati zizindikiro sizingathe, mungapatsidwe mankhwala a corticosteroid monga prednisone.

Matendawa amangochira okha. Awiri mwa atatu mwa ana omwe ali ndi IgA vasculitis ali ndi gawo limodzi lokha. Gawo limodzi mwa atatu mwa ana ali ndi magawo ambiri. Anthu ayenera kutsatira mwatsatanetsatane kwa miyezi isanu ndi umodzi pambuyo pamagawo kuti ayang'ane zizindikiro za matenda a impso. Akuluakulu ali pachiwopsezo chachikulu chotenga matenda a impso.

Zovuta zingaphatikizepo:

• Kuthira magazi m'thupi
• Kutsekereza kwa matumbo (mwa ana)
  
• Mavuto a impso (nthawi zambiri)

Itanani omwe akukuthandizani ngati:

• Mumakhala ndi zizindikiro za IgA vasculitis, ndipo zimatha masiku opitilira ochepa.
• Muli ndi mkodzo wachikuda kapena mkodzo wotsika pambuyo pazochitikazo.

Immunoglobulin A vasculitis; Leukocytoclastic vasculitis; Henoch-Schönlein purpura; HSP

• Henoch-Schonlein purpura pamiyendo yakumunsi
• Henoch-Schonlein purpura
• Henoch-Schonlein purpura
• Henoch-Schonlein purpura
• Henoch-Schonlein purpura pamapazi a khanda
• Henoch-Schonlein purpura pamiyendo ya khanda
• Henoch-Schonlein purpura pamiyendo ya khanda
• Henoch-Schonlein purpura pamiyendo

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Feehally J, FLoege J. Immunoglobulin A nephropathy ndi IgA vasculitis (Henoch-Schönlein purpura). Mu: Feehally J, Floege J, Tonelli M, Johnson RJ, olemba. Chachikulu Chachipatala Nephrology. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier; 2019: chaputala 23.

Hahn D, Hodson EM, Willis NS, Craig JC. Njira zopewera ndi kuchiritsa matenda a impso ku Henoch-Schönlein purpura (HSP). Dongosolo La Cochrane Syst Rev. 2015; (8): CD005128. PMID: 26258874 www.ncbi.nlm.nih.gov/pubmed/ 26258874.

Lu S, Liu D, Xiao J, ndi al. Kuyerekeza pakati pa akulu ndi ana omwe ali ndi Henoch-Schönlein purpura nephritis. Wodwala Nephrol. 2015; 30 (5): 791-796. PMID: 25481021 www.ncbi.nlm.nih.gov/pubmed/25481021. (Adasankhidwa)

Patterson JW. Njira ya vasculopathic reaction. Mu: Patterson JW, mkonzi. Matenda a Khungu la Weedon. Wolemba 4. Philadelphia, PA: Elsevier Churchill Livingstone; 2016: mutu 8.

Sunderkötter CH, Zelger B, Chen KR, ndi al. Nomenclature ya cutaneous vasculitis: Dermatologic addendum ku 2012 yokonzedwanso ku International Chapel Hill Consensus Conference Nomenclature ya Vasculitides. Nyamakazi Rheumatol. 2018; 70 (2): 171-184. (Adasankhidwa) PMID: 29136340 www.ncbi.nlm.nih.gov/pubmed/29136340. (Adasankhidwa)