Kusowa kwa Factor V

Kuperewera kwa Factor V ndimatenda akumwa omwe amapitilira m'mabanja. Zimakhudza kuthekera kwa magazi kuundana.

Kutseketsa magazi ndichinthu chovuta kwambiri chophatikiza mapuloteni 20 osiyanasiyana m'madzi am'magazi. Mapuloteniwa amatchedwa magazi coagulation factor.

Kulephera kwa Factor V kumachitika chifukwa chosowa chinthu V. Zinthu zina zotseka magazi zikachepa kapena zikusowa, magazi anu sawumitsa bwino.

Kusowa kwa Factor V ndikosowa. Itha kuyambitsidwa ndi:

• Cholakwika V jini yomwe imadutsa m'mabanja (obadwa nayo)
• Mankhwala oteteza thupi omwe amalepheretsa chinthu chofunikira V kugwira ntchito

Mutha kupanga antibody yomwe imasokoneza factor V:

• Atabereka
• Pambuyo pochiritsidwa ndi mtundu wina wa ulimbo wa fibrin
• Pambuyo pa opaleshoni
• Ndi matenda omwe amadzichotsera okha komanso khansa zina

Nthawi zina chifukwa chake sichidziwika.

Matendawa amafanana ndi hemophilia, kupatula kutuluka magazi m'malo ophatikizana sikofala. Mumtundu wobadwa nawo wa kusowa kwa V V, banja lomwe lili ndi vuto lakutaya magazi limakhala pachiwopsezo.

Kutaya magazi kwambiri ndi msambo komanso pambuyo pobereka kumachitika nthawi zambiri. Zizindikiro zina zitha kuphatikiza:

• Magazi pakhungu
• Kutuluka magazi m'kamwa
• Kuvulala kwambiri
• Kutulutsa magazi m'mphuno
• Kutaya magazi nthawi yayitali kapena mopitilira muyeso ndi opaleshoni kapena zoopsa
• Chitsa cha umbilical chikutuluka

Kuyesa kopeza kusowa kwa V ndiko:

• Factor V kuyesa
• Kuyesedwa kwa magazi, kuphatikiza nthawi yapadera ya thromboplastin (PTT) ndi nthawi ya prothrombin
• Nthawi yokhetsa magazi

Mudzapatsidwa madzi am'magazi am'magazi kapena ma infusions atsopano achisanu atadwala magazi kapena mutachitidwa opaleshoni. Mankhwalawa adzathetsa kusowa kwakanthawi.

Maganizo ake ndi abwino podziwa matenda ndi chithandizo choyenera.

Kutaya magazi kwambiri (kukha magazi) kumatha kuchitika.

Pitani kuchipinda chodzidzimutsa kapena itanani 911 kapena nambala yadzidzidzi yakomweko ngati mwataya magazi mosadziwika bwino kapena kwakanthawi.

Parahemophilia; Matenda a Owren; Kusokonezeka kwa magazi - chinthu V kusowa

• Mapangidwe a magazi
• Kuundana kwamagazi

Gailani D, Wheeler AP, Neff AT. Zofooka zambiri zomwe zimachitika nthawi zambiri. Mu: Hoffman R, Benz EJ, Silberstein LE, et al, olemba. Hematology: Mfundo Zoyambira ndi Zochita. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 137.

Ragni MV. Matenda a hemorrhagic: coagulation factor deficience. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 165.

Scott JP, Chigumula VH. Zofooka zobwera chifukwa cha magazi m'masamba (zovuta zamagazi). Mu: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, olemba. Nelson Textbook of Pediatrics. Wolemba 21. Philadelphia, PA: Elsevier; 2020: chap 503.