Kulephera kwa Vitamini B12 kuchepa kwa magazi

Kuchepa kwa magazi m'thupi ndimomwe thupi limakhala lilibe maselo ofiira okwanira okwanira. Maselo ofiira ofiira amapereka mpweya kumatenda amthupi. Pali mitundu yambiri ya kuchepa kwa magazi m'thupi.

Kulephera kwa Vitamini B12 ndi kuchepa kwama cell ofiira ofiira chifukwa chakusowa kwa vitamini B12.

Thupi lanu limafunikira vitamini B12 kuti lipange maselo ofiira. Pofuna kupereka vitamini B12 m'maselo anu:

• Muyenera kudya zakudya zomwe zili ndi vitamini B12, monga nyama, nkhuku, nkhono, mazira, tirigu wam'mawa wokhala ndi mipanda yolimba, ndi zopangira mkaka.
• Thupi lanu liyenera kuyamwa vitamini B12 wokwanira. Puloteni yapadera, yotchedwa intrinsic factor, imathandiza thupi lanu kuchita izi. Puloteni iyi imatulutsidwa ndimaselo m'mimba.

Kuperewera kwa vitamini B12 kumatha kukhala chifukwa cha zakudya, kuphatikizapo:

• Kudya zakudya zamasamba okhwima
• Zakudya zoperewera kwa makanda
• Zakudya zoperewera panthawi yoyembekezera

Matenda ena amatha kupangitsa kuti thupi lanu likhale ndi mavitamini B12 okwanira. Zikuphatikizapo:

• Kumwa mowa
• Matenda a Crohn, matenda a leliac, matenda opatsirana ndi tapeworm ya nsomba, kapena mavuto ena omwe amalepheretsa thupi lanu kugaya zakudya
• Kuchepa kwa magazi, mtundu wa vitamini B12 kuchepa kwa magazi komwe kumachitika thupi lanu likamawononga maselo omwe amapanga zinthu zamkati
• Kuchita opaleshoni komwe kumachotsa magawo ena am'mimba kapena m'matumbo ang'onoang'ono, monga maopaleshoni ena ochepetsa thupi
• Kutenga ma antiacids ndi mankhwala ena akumva kutentha kwa chifuwa kwa nthawi yayitali
• Kugwiritsa ntchito "mpweya woseketsa" (nitrous oxide)

Simungakhale ndi zizindikilo. Zizindikiro zingakhale zofatsa.

Zizindikiro zimatha kuphatikiza:

• Kutsekula m'mimba kapena kudzimbidwa
• Kutopa, kusowa mphamvu, kapena kupepuka mutayimirira kapena kuyesetsa
• Kutaya njala
• Khungu lotumbululuka
• Kumva kukwiya
• Kupuma pang'ono, makamaka panthawi yochita masewera olimbitsa thupi
• Kutupa, lilime lofiira kapena chingamu chotuluka magazi

Ngati muli ndi mavitamini B12 ochepa kwa nthawi yayitali, mutha kuwonongeka ndi mitsempha. Zizindikiro za kuwonongeka kwa mitsempha zimaphatikizapo:

• Kusokonezeka kapena kusintha kwa malingaliro (dementia) pamavuto akulu
• Mavuto akukhazikika
• Psychosis (kutaya kulumikizana ndi zenizeni)
• Kutaya malire
• Kufooka ndi kumva kulira kwa manja ndi mapazi
• Ziwerengero

Wothandizira zaumoyo adzayesa. Izi zitha kuwulula zovuta ndi malingaliro anu.

Mayeso omwe angachitike ndi awa:

• Kuwerengera kwathunthu kwa magazi (CBC)
• Kuwerengera kwa reticulocyte
• Mulingo wa Lactate dehydrogenase (LDH)
• Mlingo wa seramu bilirubin
• Mulingo wa Vitamini B12
• Mlingo wa Methylmalonic acid (MMA)
• Mlingo wa serum homocysteine ​​(amino acid wopezeka m'magazi)

Njira zina zomwe zingachitike ndi monga:

• Esophagogastroduodenoscopy (EGD) kuti mufufuze m'mimba
• Enteroscopy kuti aone m'matumbo ang'onoang'ono
• Matenda a mafupa ngati matendawa sakudziwika bwinobwino

Chithandizo chimadalira chifukwa cha kuchepa kwa kuchepa kwa magazi kwa B12.

Cholinga cha chithandizo ndikuwonjezera kuchuluka kwanu kwa vitamini B12.

• Chithandizocho chingaphatikizepo kuwombera vitamini B12 kamodzi pamwezi. Ngati muli ndi B12 yotsika kwambiri, mungafunike kuwombera kambiri koyambirira. Ndizotheka kuti mungafunike kuwombera mwezi uliwonse kwa moyo wanu wonse.
• Anthu ena amatha kulandira chithandizo akamamwa mankhwala a vitamini B12 pakamwa.

Wothandizira anu akulimbikitsanso kuti mudye zakudya zosiyanasiyana.

Anthu omwe ali ndi vuto la kuchepa kwa magazi nthawi zambiri amachita bwino ndi chithandizo.

Kulephera kwa vitamini B12 kwa nthawi yayitali kumatha kuwononga mitsempha. Izi zitha kukhala zachikhalire ngati simumayamba kulandira chithandizo mkati mwa miyezi isanu ndi umodzi kuyambira pomwe matenda anu akuyamba.

Kulephera kwa Vitamini B12 nthawi zambiri kumayankha bwino kuchipatala. Zitha kukhala bwino pakachiritsidwa chomwe chikuyambitsa vuto.

Mzimayi yemwe ali ndi mulingo wochepa wa B12 atha kukhala ndi kachilombo koyipa ka Pap smear. Izi ndichifukwa choti kuchepa kwa vitamini B12 kumakhudza momwe maselo ena (ma epithelial cell) amawonekera.

Itanani omwe akukuthandizani ngati muli ndi zina mwazizindikiro zakuchepa kwa magazi m'thupi.

Mutha kupewa kuchepa kwa magazi chifukwa chosowa vitamini B12 mwa kudya zakudya zopatsa thanzi.

Mavitamini a vitamini B12 amatha kuteteza kuchepa kwa magazi ngati mwachitidwa opareshoni yodziwika kuti imayambitsa vuto la vitamini B12.

Kuzindikira msanga komanso kulandira chithandizo mwachangu kumatha kuchepetsa kapena kupewa zovuta zokhudzana ndi kuchepa kwa vitamini B12.

Kuchepa kwa magazi Megaloblastic macrocytic

• Anemia of Megaloblastic - kuwona kwa maselo ofiira ofiira
• Hypersegmented PMN (Kutseka)

Antony AC. Zovuta za Megaloblastic. Mu: Hoffman R, Benz EJ, Silberstein LE, et al, olemba. Hematology: Mfundo Zoyambira ndi Zochita. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 39.

Zikutanthauza RT. Yandikirani ku anemias. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 149.

Perez DL, Murray ED, Mtengo BH. Kukhumudwa ndi psychosis mumachitidwe amitsempha. Mu: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, olemba. Neurology ya Bradley mu Kuchita Zachipatala. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2016: mutu 10.