Meningitis - cryptococcal

Cryptococcal meningitis ndi matenda opatsirana a mafinya omwe amaphimba ubongo ndi msana. Ziphuphuzi zimatchedwa meninges.

Nthawi zambiri, cryptococcal meningitis imayambitsidwa ndi bowa Cryptococcus neoformans. Mafangayi amapezeka m'nthaka padziko lonse lapansi. Cryptococcus gattii Ikhozanso kuyambitsa matenda a ubongo, koma mawonekedwewa amathanso kuyambitsa matenda kwa odwala omwe ali ndi chitetezo chamthupi.

Mtundu uwu wa meninjaitisi sunafalikire kwa munthu wina. Nthawi zambiri, imafalikira kudzera m'magazi kupita kuubongo kuchokera kumalo ena mthupi omwe ali ndi matendawa.

Cryptococcus neoformans meningitis nthawi zambiri imakhudza anthu omwe ali ndi chitetezo chamthupi chofooka, kuphatikiza anthu omwe ali ndi:

• Edzi
• Cirrhosis (mtundu wa matenda a chiwindi)
• Matenda a shuga
• Khansa ya m'magazi
• Lymphoma
• Sarcoidosis
• Kuika thupi

Matendawa ndi osowa mwa anthu omwe ali ndi chitetezo chamthupi ndipo alibe mavuto azaumoyo kwakanthawi.

Mtundu uwu wa meningitis umayamba pang'onopang'ono, patadutsa masiku angapo mpaka milungu ingapo. Zizindikiro zimaphatikizapo:

• Malungo
• Ziwerengero
• Mutu
• Kusintha kwa malingaliro (chisokonezo)
• Nseru ndi kusanza
• Kumvetsetsa kuunika
• Khosi lolimba

Wothandizira zaumoyo wanu adzakufunsani ndikufunsani za zomwe mukudwala.

Kutsekemera kwa lumbar (tapampopi) kumagwiritsidwa ntchito pozindikira matenda a meningitis. Pachiyesochi, mtundu wa cerebrospinal fluid (CSF) umachotsedwa msana wanu ndikuyesedwa.

Mayesero ena omwe angachitike ndi awa:

• Chikhalidwe chamagazi
• X-ray pachifuwa
• Cryptococcal antigen mu CSF kapena magazi, kufunafuna ma antibodies
• CSF kuyesa kuwerengera kwama cell, glucose, ndi protein
• Kujambula kwa CT pamutu
• Utoto wa gramu, mabanga ena apadera, ndi chikhalidwe cha CSF

Mankhwala osokoneza bongo amagwiritsidwa ntchito pochiza matendawa. Mitsempha ya m'mitsempha (IV, kudzera mumitsempha) ndi amphotericin B ndiye mankhwala ofala kwambiri. Nthawi zambiri amaphatikizidwa ndi mankhwala am'kamwa otchedwa 5-flucytosine.

Mankhwala ena amkamwa, fluconazole, pamlingo waukulu amathanso kukhala othandiza. Ngati kuli kofunikira, adzalembedweratu pamapeto pa matendawa.

Anthu omwe amachira ku cryptococcal meningitis amafunikira mankhwala a nthawi yayitali kuti ateteze matendawa kuti asabwerere. Anthu omwe ali ndi chitetezo chamthupi chofooka, monga omwe ali ndi HIV / AIDS, adzafunikiranso chithandizo chanthawi yayitali kuti chitetezo chawo chitetezeke.

Zovuta izi zimatha kupezeka ndi matendawa:

• Kuwonongeka kwa ubongo
• Kumva kapena kutaya masomphenya
• Hydrocephalus (CSF wochuluka mu ubongo)
• Kugwidwa
• Imfa

Amphotericin B itha kukhala ndi zovuta monga:

• Nseru ndi kusanza
• Malungo ndi kuzizira
• Kupweteka pamodzi ndi minofu
• Kuwonongeka kwa impso

Itanani nambala yadzidzidzi yakomweko (monga 911) ngati mungakhale ndi zina mwazizindikiro zazikulu zomwe zatchulidwa pamwambapa. Meningitis imatha kukhala matenda owopsa.

Itanani nambala yanu yakadzidzidzi kapena pitani kuchipinda chadzidzidzi ngati mukukayikira kuti meningitis ili mwa mwana yemwe ali ndi izi:

• Kudyetsa zovuta
• Kulira kwakukulu
• Kukwiya
• Malungo osatha, osadziwika

Minyewa ya Cryptococcal

• Central dongosolo lamanjenje ndi zotumphukira zamanjenje

Malo Othandizira Kuteteza ndi Kuteteza tsamba lawebusayiti. Fungal meninjaitisi. www.cdc.gov/meningitis/fungal.html. Idasinthidwa pa Ogasiti 06, 2019. Idapezeka pa February 18, 2021.

Kauffman CA, Chen S. Cryptococcosis. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 317.

JR wangwiro. Kubwezeretsa (Cryptococcus neoformans ndipo Cryptococcus gattii). Mu: Bennett JE, Dolin R, Blaser MJ, olemba., Eds. Mandell, Douglas, ndi Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020: chap 262.