Kuchulukitsa kwamchiberekero cha ma androgens

Kuchulukitsa kwa ovarijeni kwama androgens ndimomwe m'mimba mwake mumapangira ma testosterone ambiri. Izi zimabweretsa kukula kwa mawonekedwe achimuna mwa mkazi. Androgens ochokera mbali zina za thupi amathanso kuyambitsa mawonekedwe amphongo mwa amayi.

Mwa amayi athanzi, thumba losunga mazira ndi ma adrenal gland amatulutsa pafupifupi 40% mpaka 50% ya testosterone ya thupi. Zotupa za thumba losunga mazira ndi polycystic ovary syndrome (PCOS) zimatha kuyambitsa michere yambiri ya androgen.

Cushing matenda ndi vuto ndi pituitary gland yomwe imabweretsa kuchuluka kwa ma corticosteroids. Corticosteroids imapangitsa kusintha kwa thupi lachimuna mwa akazi. Zotupa m'matenda a adrenal amathanso kuyambitsa ma androgens ochulukirapo ndipo zimatha kuyambitsa machitidwe amthupi mwa akazi.

Kuchuluka kwa ma androgens mwa mkazi kumatha kuyambitsa:

• Ziphuphu
• Kusintha kwa mawonekedwe achikazi
• Kuchepetsa kukula kwa bere
• Wonjezerani tsitsi la thupi mumachitidwe amphongo, monga pamaso, pachibwano, ndi pamimba
• Kusowa kwa msambo (amenorrhea)
• Khungu lamafuta

Zosinthazi zitha kuchitika:

• Wonjezerani kukula kwa nkongoyo
• Kuzama kwa mawu
• Wonjezerani minofu
• Tsitsi lakuthwa ndi kutayika kwa tsitsi patsogolo pamutu mbali zonse ziwiri za mutu

Wothandizira zaumoyo wanu adzakuyesani. Kuyezetsa magazi ndi kuyerekezera kulikonse kolamulidwa kumadalira zizindikiro zanu, koma kungaphatikizepo:

• Mayeso a 17-hydroxyprogesterone
• Mayeso a ACTH (achilendo)
• Kuyezetsa magazi m'thupi
• Kujambula kwa CT
• DHEA kuyesa magazi
• Mayeso a shuga
• Kuyesa kwa insulini
• Pelvic ultrasound
• Kuyesa kwa Prolactin (ngati nthawi zimabwera kawirikawiri kapena ayi)
• Mayeso a testosterone (testosterone yaulere komanso yathunthu)
• Mayeso a TSH (ngati pali tsitsi)

Chithandizo chimadalira vuto lomwe limayambitsa kuchuluka kwa androgen. Mankhwala atha kuperekedwa kuti achepetse kupangidwa kwa tsitsi mwa amayi omwe ali ndi tsitsi lochulukirapo, kapena kuwongolera kusamba. Nthawi zina, pamafunika opaleshoni kuti muchotse chotupa cha m'mimba kapena adrenal.

Kuchiza bwino kumatengera chifukwa cha kuchuluka kwa androgen. Ngati vutoli limayambitsidwa ndi chotupa cha m'mimba, opaleshoni yochotsa chotupacho ingathetse vutolo. Zotupa zambiri zam'mimba sizikhala ndi khansa (zabwino) ndipo sizibweranso zitachotsedwa.

Mu polycystic ovary syndrome, njira zotsatirazi zitha kuchepetsa zizindikilo zomwe zimayambitsidwa ndi milingo yayikulu ya androgen:

• Kuwunika mosamala
• Kuchepetsa thupi
• Kusintha kwa zakudya
• Mankhwala
• Kuchita masewera olimbitsa thupi mwamphamvu

Kusabereka komanso zovuta nthawi yapakati zimatha kuchitika.

Azimayi omwe ali ndi vuto la ovary polycystic atha kukhala pachiwopsezo chachikulu cha:

• Matenda a shuga
• Kuthamanga kwa magazi
• Cholesterol wokwera
• Kunenepa kwambiri
• Khansara ya chiberekero

Azimayi omwe ali ndi matenda a polycystic ovary amatha kuchepetsa kusintha kwawo kwakanthawi kwakanthawi pochepetsa thupi mwa kudya zakudya zopatsa thanzi komanso kuchita masewera olimbitsa thupi pafupipafupi.

• Kuchuluka kwa mazira ochuluka
• Kukula kwazinthu

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