Chotupa cha Hypothalamic

Chotupa cha hypothalamic ndikumera kosazolowereka kwa hypothalamus gland, yomwe imapezeka muubongo.

Zomwe zimayambitsa zotupa za hypothalamic sizikudziwika. Zikuwoneka kuti zimachokera ku kuphatikiza kwa majini ndi chilengedwe.

Kwa ana, zotupa zambiri za hypothalamic ndi gliomas. Gliomas ndi mtundu wofala wa chotupa chaubongo chomwe chimachokera pakukula kosazolowereka kwamaselo am'magazi, omwe amathandizira maselo amitsempha. Gliomas imatha kuchitika msinkhu uliwonse. Nthawi zambiri amakhala okhwima mwa akulu kuposa ana.

Kwa akulu, zotupa mu hypothalamus ndizomwe zimayambitsa khansa yomwe yafalikira kuchokera ku chiwalo china.

Anthu omwe ali ndi neurofibromatosis (cholowa cholowa) ali pachiwopsezo chachikulu chotupa chotere. Anthu omwe alandila chithandizo chama radiation ali pachiwopsezo chowonjezeka chotupa zotupa.

Zotupa izi zimatha kuyambitsa zizindikilo zingapo:

• Zokhumudwitsa "zapamwamba"
• Kulephera kukula bwino (kusakula bwino kwa ana)
• Mutu
• Kutengeka
• Kutaya mafuta ndi thupi (cachexia)

Zizindikiro izi zimawoneka kawirikawiri mwa ana omwe zotupa zawo zimakhudza kutsogolo kwa hypothalamus.

Zotupa zina zimatha kuyambitsa masomphenya. Ngati zotupazo zimalepheretsa kutuluka kwa msana wam'mimba, mutu ndi tulo zimatha kubwera chifukwa chakumwa kwamadzi muubongo (hydrocephalus).

Anthu ena amatha kugwidwa chifukwa cha zotupa zamaubongo. Anthu ena amatha kutha msinkhu msinkhu chifukwa cha kusintha kwa ntchito yamatenda am'mimba.

Wothandizira zaumoyo wanu amatha kuwona zizindikilo za chotupa cha hypothalamic panthawi yoyezetsa magazi. Kuyezetsa kwa ubongo ndi zamanjenje (zamitsempha), kuphatikiza kuyesa kwa mawonekedwe, zitha kuchitika. Kuyesedwa kwamagazi chifukwa cha kusamvana kwa mahomoni kumatha kulamulidwanso.

Kutengera zotsatira za mayeso ndi kuyezetsa magazi, CT scan kapena MRI scan imatha kudziwa ngati muli ndi chotupa cha hypothalamic.

Kuyesa kwamasamba owonera kumatha kuchitidwa kuti muwone ngati kutayika kwa masomphenya ndikuwona ngati vutoli likukula kapena likuipiraipira.

Chithandizocho chimadalira momwe chotupacho chimakhalira, komanso ngati ndi glioma kapena khansa yamtundu wina. Chithandizochi chingaphatikizepo kuphatikiza maopaleshoni, radiation, ndi chemotherapy.

Mankhwala apadera a radiation amatha kuyang'ana pachotupacho. Zitha kukhala zothandiza ngati opaleshoni, osakhala pachiwopsezo chochepa cha minofu yozungulira. Kutupa kwa ubongo komwe kumayambitsa chotupa kumafunikira kuthandizidwa ndi steroids.

Zotupa za Hypothalamic zimatha kutulutsa mahomoni kapena kukhudza kupanga mahomoni, zomwe zimabweretsa kusamvana komwe kumafunika kukonzedwa. Nthawi zina, mahomoni angafunike kusinthidwa kapena kuchepetsedwa.

Nthawi zambiri mutha kuthandiza kupsinjika kwa matenda polowa nawo gulu lothandizira pomwe mamembala amagawana zomwe amakumana nazo pamavuto.

Maganizo ake amatengera:

• Mtundu wa chotupa (glioma kapena mtundu wina)
• Malo otupa
• Kalasi ya chotupa
• Kukula kwa chotupa
• Zaka zanu ndi thanzi lanu lonse

Mwambiri, ma gliomas mwa akulu amakhala owopsa kuposa ana ndipo nthawi zambiri amakhala ndi zotsatira zoyipa. Zotupa zomwe zimayambitsa hydrocephalus zimatha kubweretsa zovuta zambiri, ndipo zimafunikira kuchitidwa opaleshoni.

Zovuta za opaleshoni yaubongo zitha kuphatikizira:

• Magazi
• Kuwonongeka kwa ubongo
• Imfa (kawirikawiri)
• Matenda

Khunyu limatha chifukwa cha chotupacho kapena njira iliyonse yochitira opaleshoni yaubongo.

Hydrocephalus imatha kuchitika ndi zotupa zina ndipo imatha kuchitidwa opareshoni kapena catheter yoyikidwa muubongo kuti ichepetse kuthamanga kwa msana.

Zowopsa zothandizidwa ndi radiation zimaphatikizaponso kuwonongeka kwa maselo abongo abwino ma cell a chotupa akawonongeka.

Zotsatira zoyipa kuchokera ku chemotherapy zimaphatikizapo kusowa kwa njala, nseru, kusanza, ndi kutopa.

Itanani omwe akukuthandizani ngati inu kapena mwana wanu muli ndi vuto lililonse la chotupa cha hypothalamic. Kuyesedwa pafupipafupi kuchipatala kumatha kuzindikira zizindikiro zoyambirira za vuto, monga kunenepa kwambiri kapena kutha msinkhu.

Hypothalamic glioma; Hypothalamus - chotupa

Goodden J, Mallucci C. Optic njira yama hypothalamic gliomas. Mu: Winn HR, mkonzi. Opaleshoni ya Youmans ndi Winn Neurological. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2017: mutu 207.

Weiss RE. Neuroendocrinology ndi dongosolo la neuroendocrine. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: mutu 210.