Kubadwa kwa fibrinogen kusowa

Kuperewera kwa kubadwa kwa fibrinogen ndikosowa kwambiri, komwe kumatengera magazi komwe magazi samatseka bwino. Zimakhudza mapuloteni otchedwa fibrinogen. Puloteni iyi imafunika kuti magazi aumbike.

Matendawa amadza chifukwa cha majini achilendo. Fibrinogen imakhudzidwa kutengera momwe majini amabadwira:

• Pamene jini yosazolowereka imachotsedwa kwa makolo onse, munthu amakhala ndi vuto la fibrinogen (afibrinogenemia).
• Pamene jini yachilendo imaperekedwa kuchokera kwa kholo limodzi, munthu amakhala ndi kuchepa kwa fibrinogen (hypofibrinogenemia) kapena vuto la ntchito ya fibrinogen (dysfibrinogenemia). Nthawi zina, mavuto awiriwa a fibrinogen amatha kuchitika mwa munthu yemweyo.

Anthu omwe alibe fibrinogen atha kukhala ndi izi:

• Kulalata mosavuta
• Kutuluka magazi kuchokera ku umbilical atangobadwa kumene
• Kutuluka magazi m'matumbo
• Kutuluka magazi muubongo (kosowa kwambiri)
• Kutuluka magazi m'malo olumikizirana mafupa
• Kutaya magazi kwambiri pambuyo povulala kapena kuchitidwa opaleshoni
• Kutulutsa magazi m'mphuno komwe sikumatha mosavuta

Anthu omwe ali ndi kuchepa kwa fibrinogen amatuluka magazi pafupipafupi ndipo magazi samakhala owopsa. Omwe ali ndi vuto ndi magwiridwe antchito a fibrinogen nthawi zambiri samakhala ndi zisonyezo.

Ngati wothandizira zaumoyo akukayikira vutoli, mudzayesedwa labu kuti mutsimikizire mtundu wa kukula kwa matendawa.

Mayeso ndi awa:

• Nthawi yokhetsa magazi
• Mayeso a Fibrinogen ndi nthawi yobwezeretsanso kuti muwone mulingo wa fibrin ndi mtundu wake
• Nthawi yapadera ya thromboplastin (PTT)
• Nthawi ya Prothrombin (PT)
• Nthawi ya Thrombin

Mankhwalawa atha kugwiritsidwa ntchito popanga magazi kapena kukonzekera opaleshoni:

• Cryoprecipitate (mankhwala opangidwa ndi magazi omwe amakhala ndi fibrinogen yambiri ndi zina zotseka)
• Fibrinogen (RiaSTAP)
• Plasma (gawo lamadzi lamagazi lomwe limakhala ndi zotseka)

Anthu omwe ali ndi vutoli ayenera kulandira katemera wa hepatitis B. Kuikidwa magazi nthawi zambiri kumawonjezera chiopsezo chanu chotenga matenda a chiwindi.

Kutaya magazi kwambiri ndikofala ndi vutoli. Magawo awa atha kukhala owopsa, mwinanso owopsa. Kutuluka magazi muubongo ndi komwe kumayambitsa kufa kwa anthu omwe ali ndi vutoli.

Zovuta zingaphatikizepo:

• Kuundana kwamagazi ndi chithandizo
• Kukula kwa ma antibodies (inhibitors) ku fibrinogen ndi chithandizo
• Kutuluka m'mimba
• Kupita padera
• Kung'ambika kwa ndulu
• Kuchira pang'onopang'ono kwa mabala

Itanani omwe akukuthandizani kapena mupeze chithandizo chadzidzidzi ngati mwakhala mukutuluka magazi kwambiri.

Uzani dokotala wanu musanamuchite opaleshoni ngati mukudziwa kapena mukuganiza kuti muli ndi vuto lakutaya magazi.

Uwu ndi mkhalidwe wobadwa nawo. Palibe njira yodziwika yopewera.

Afibrinogenemia; Hypofibrinogenemia; Dysfibrinogenemia; Factor kusowa

Gailani D, Wheeler AP, Neff AT. Zofooka zambiri zomwe zimachitika nthawi zambiri. Mu: Hoffman R, Benz EJ, Silberstein LE, et al, olemba. Hematology: Mfundo Zoyambira ndi Zochita. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 137.

Ragni MV. Matenda a hemorrhagic: coagulation factor deficience. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. Wolemba 25. Philadelphia, PA: Elsevier Saunders; 2016: chap 174.