Mayeso a 17-hydroxycorticosteroids mkodzo

Mayeso 17-hydroxycorticosteroids (17-OHCS) amayesa mulingo wa 17-OHCS mumkodzo.

Muyenera kuyesa mkodzo wa maola 24. Muyenera kusonkhanitsa mkodzo kwa maola 24. Wothandizira zaumoyo wanu adzakuuzani momwe mungachitire izi. Tsatirani malangizo ndendende.

Wothandizira adzakulangizani, ngati kuli kofunikira, kusiya mankhwala omwe angasokoneze mayeso. Izi zingaphatikizepo:

• Mapiritsi oletsa kubereka omwe ali ndi estrogen
• Maantibayotiki ena
• Glucocorticoids

Chiyesocho chimaphatikizapo kukodza kokha. Palibe kusapeza.

17-OHCS ndi chinthu chomwe chimapangidwa chiwindi ndi ziwalo zina zathupi zikawononga steroid hormone cortisol.

Kuyesaku kungathandize kudziwa ngati thupi limapanga cortisol yambiri. Kuyesaku kungagwiritsidwe ntchito kuzindikira matenda a Cushing. Ichi ndi vuto lomwe limachitika thupi likakhala ndi cortisol yokwanira.

Vuto la mkodzo ndi mkodzo creatinine nthawi zambiri zimachitika ndi mayeso a 17-OHCS nthawi yomweyo. Izi zimathandiza wothandizira kutanthauzira mayeso.

Kuyesaku sikuchitika kawirikawiri pano. Kuyezetsa kwaulere kwa mkodzo wa cortisol ndiyeso loyesera bwino la matenda a Cushing.

Makhalidwe abwino:

• Amuna: 3 mpaka 9 mg / maola 24 (8.3 mpaka 25 olmol / maola 24)
• Mkazi: 2 mpaka 8 mg / maola 24 (5.5 mpaka 22 olmol / maola 24)

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyanasiyana kapena amayesa mitundu yosiyanasiyana. Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Mulingo woposa 17-OHCS ukhoza kuwonetsa:

• Mtundu wa Cushing syndrome womwe umayambitsidwa ndi chotupa mu adrenal gland chomwe chimapanga cortisol
• Matenda okhumudwa
• Mankhwala a Hydrocortisone
• Kusowa zakudya m'thupi
• Kunenepa kwambiri
• Mimba
• Chifukwa cha mahomoni cha kuthamanga kwambiri kwa magazi
• Kupsinjika kwakuthupi kapena kwamaganizidwe
• Chotupa m'matumbo kapena pena paliponse m'thupi chomwe chimatulutsa timadzi totchedwa adrenocorticotropic hormone (ACTH)

Zomwe zili zochepa kuposa 17-OHCS zitha kuwonetsa:

• Matumbo a Adrenal sakupanga mahomoni okwanira
• Matenda a pituitary samatulutsa mahomoni okwanira
• Kusowa kwa michere ya cholowa
• Opaleshoni yapita yochotsa adrenal gland

Kukodza madzi opitilira 3 malita patsiku (polyuria) kumatha kupanga zotsatira za mayeso ngakhale kukwera kwa cortisol kumakhala kwachilendo.

Palibe zowopsa pamayesowa.

17-OH ma corticosteroids; 17-OHCS

Chernecky CC, Berger BJ. 17-hydroxycorticosteroids (17-OHCS) - mkodzo wamaola 24. Mu: Chernecky CC, Berger BJ, olemba., Eds. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. St Louis, MO: Elsevier Saunders; 2013: 659-660.

Juszczak A, Morris DG, Grossman AB, Nieman LK (Adasankhidwa) Matenda a Cushing. Mu: Jameson JL, De Groot LJ, de Kretser DM, et al, olemba. Endocrinology: Akuluakulu ndi Ana. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier Saunders; 2016: chap 13.