Antimitochondrial antibody

Antimitochondrial antibodies (AMA) ndi zinthu (ma antibodies) omwe amapangidwa motsutsana ndi mitochondria. Mitochondria ndi gawo lofunikira lamaselo. Ndiwo gwero lamphamvu mkati mwa maselo. Izi zimathandiza kuti maselo azigwira ntchito moyenera.

Nkhaniyi ikufotokoza za kuyesa magazi komwe kumayeza kuchuluka kwa AMA m'magazi.

Muyenera kuyesa magazi. Nthawi zambiri amatengedwa kuchokera mumtsempha. Njirayi imatchedwa venipuncture.

Wothandizira zaumoyo wanu akhoza kukuwuzani kuti musadye kapena kumwa chilichonse kwa maola 6 musanayezedwe (nthawi zambiri usiku umodzi).

Pamene singano imayikidwa kuti ikoke magazi, anthu ena amamva kupweteka pang'ono. Ena amangomva kuti amangobaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupindika.

Mungafunike mayesowa ngati muli ndi zizindikiro za kuwonongeka kwa chiwindi. Mayesowa amagwiritsidwa ntchito kwambiri kuti azindikire biliary cholangitis, yemwe kale amatchedwa biliary cirrhosis (PBC).

Chiyesocho chingagwiritsidwenso ntchito posiyanitsa pakati pa matenda am'mimba okhudzana ndi matenda amchiberekero ndi mavuto a chiwindi chifukwa cha zifukwa zina monga kutsekeka, chiwindi cha chiwindi, kapena matenda ena osokoneza bongo.

Nthawi zambiri, kulibe ma antibodies omwe alipo.

Kuyesaku ndikofunikira pakuzindikira PBC. Pafupifupi anthu onse omwe ali ndi vutoli ayesedwa kuti ali ndi kachilomboka. Nthawi zambiri munthu wopanda vutoli amakhala ndi zotsatira zabwino. Komabe, anthu ena omwe ali ndi mayeso abwino a AMA ndipo palibe chizindikiro china cha matenda a chiwindi chomwe chitha kupita ku PBC pakapita nthawi.

Nthawi zambiri, zotsatira zosazolowereka zimapezekanso chifukwa cha mitundu ina ya matenda a chiwindi ndi matenda ena amthupi okha.

Zowopsa zokoka magazi ndizochepa koma zimatha kuphatikiza:

• Kutaya magazi kwambiri
• Kukomoka kapena kumva mopepuka
• Hematoma (magazi akuchuluka pansi pa khungu)
• Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)

• Kuyezetsa magazi

Otsatira U, Gershwin ME, Gish RG, et al. Maina osintha a PBC: Kuchokera ku 'cirrhosis' kupita ku 'cholangitis'. Clin Res Hepatol Gastroenterol. 2015; 39 (5): e57-e59. PMID: 26433440 www.ncbi.nlm.nih.gov/pubmed/26433440. (Adasankhidwa)

Chernecky CC, Berger BJ. A. Mu: Chernecky CC, Berger BJ, olemba, eds. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. St Louis, MO: Elsevier Saunders; 2013: 84-180.

Eaton JE, Lindor KD. Pulayimale biliary matenda enaake. Mu: Feldman M, Friedman LS, Brandt LJ, olemba. Sleisenger ndi Fordtran's Mimba ndi Matenda a Chiwindi: Pathophysiology / Diagnosis / Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016: chap 91.

Kakar S. Pulayimale biliary cholangitis. Mu: Saxena R, mkonzi. Yothandiza Hepatic Pathology: Njira Yodziwitsa. Wachiwiri ed. Philadelphia, PA: Elsevier; 2018: mutu 26.

Zhang J, Zhang W, Leung PS, ndi al. Kupitiliza kwa ma cell a B opatsirana ndi autoantigen mu primary biliary cirrhosis. Matenda a chiwindi. 2014; 60 (5): 1708-1716. PMID: 25043065 www.ncbi.nlm.nih.gov/pubmed/25043065. (Adasankhidwa)