Kuyesedwa kwa mkodzo wa PBG

Porphobilinogen (PBG) ndi amodzi mwamitundu ingapo yama porphyrins omwe amapezeka mthupi lanu. Porphyrins amathandizira kupanga zinthu zambiri zofunika mthupi. Chimodzi mwa izi ndi hemoglobin, mapuloteni m'maselo ofiira amwazi omwe amanyamula mpweya wamagazi. Porphyrins nthawi zambiri amasiya thupi lanu kudzera mumkodzo kapena chimbudzi. Ngati izi sizichitika, ma porphyrins monga PBG amatha kukhala mthupi lanu.

Nkhaniyi ikufotokoza mayeso kuti muyese kuchuluka kwa PBG mumayeso amkodzo.

Mukapereka mkodzo, umayesedwa mu labu. Izi zimatchedwa zitsanzo za mkodzo mwachisawawa.

Ngati kuli kofunikira, wothandizira zaumoyo wanu akhoza kukupemphani kuti mutenge mkodzo wanu kunyumba kwa maola 24. Izi zimatchedwa sampuli yamaora 24. Wothandizira anu adzakuuzani momwe mungachitire izi. Tsatirani malangizo ndendende.

Wothandizira anu akhoza kukuwuzani kuti musiye kumwa mankhwala omwe angakhudze zotsatira zanu. Onetsetsani kuti mukuwuza omwe akukuthandizani za mankhwala onse omwe mumamwa. Izi zikuphatikiza:

• Maantibayotiki ndi mankhwala odana ndi fungal
• Mankhwala osokoneza bongo
• Mapiritsi oletsa kubereka
• Mankhwala a shuga
• Mankhwala opweteka
• Mankhwala ogona

Osasiya kumwa mankhwala osalankhula ndi omwe akukuthandizani.

Kuyesaku kumakhudza kukodza kwanthawi zonse, ndipo palibe zovuta.

Mayesowa atha kuchitidwa ngati omwe amakupatsirani akuganiza kuti porphyria kapena vuto lina lomwe limakhudzana ndi vuto la PBG.

Pazitsanzo za mkodzo mwachisawawa, zotsatira zoyipa zoyesedwa zimawoneka ngati zachilendo.

Kuyesaku kukachitika pamayeso a mkodzo wamaola 24, mtengo wake umakhala wochepera mamiligalamu 4 maola 24 (ma micromoles 18 pa maola 24).

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyana kapena amatha kuyesa mitundu yosiyanasiyana. Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Kuchuluka kwa PBG mumkodzo kumatha kukhala chifukwa cha:

• Chiwindi
• Kupha poizoni
• Khansa ya chiwindi
• Porphyria (mitundu ingapo)

Palibe zowopsa pamayesowa.

Kuyesa kwa Porphobilinogen; Porphyria - mkodzo; PBG

• Njira yamikodzo yamwamuna

Wodzaza SJ, Wiley JS. Heme biosynthesis ndi zovuta zake: porphyrias ndi sideroblastic anemias. Mu: Hoffman R, Benz EJ, Silberstein LE, et al, olemba. Hematology: Mfundo Zoyambira ndi Zochita. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 38.

(Adasankhidwa) Riley RS, McPherson RA. Kuwunika koyambirira kwa mkodzo. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 28.