Kuyesa kwamapuloteni a Bence-Jones

Kuyesaku kumayeza kuchuluka kwa mapuloteni achilendo otchedwa Bence-Jones mapuloteni mumkodzo.

Muyenera kuyesa mkodzo woyera. Njira yoyera moyera imagwiritsidwa ntchito popewera majeremusi ochokera ku mbolo kapena kumaliseche kuti asalowe mkodzo. Kuti mutenge mkodzo wanu, wothandizira zaumoyo atha kukupatsirani chida chogwirira bwino chomwe chili ndi yankho loyeretsera komanso zopukutira. Tsatirani malangizo ndendende kuti zotsatira zake zikhale zolondola.

Chitsanzocho chimatumizidwa ku labu. Kumeneko, imodzi mwa njira zambiri imagwiritsidwa ntchito pozindikira mapuloteni a Bence-Jones. Njira imodzi, yotchedwa immunoelectrophoresis, ndiyo yolondola kwambiri.

Chiyesocho chimakodza kukodza kokha, ndipo palibe zovuta.

Mapuloteni a Bence-Jones ndi amodzi mwa ma antibodies omwe amatchedwa maunyolo opepuka. Mapuloteniwa samakhala mkodzo nthawi zambiri. Nthawi zina, thupi lanu likapanga ma antibodies ochulukirapo, mulingo wamaunyolo owunika umakweranso. Mapuloteni a Bence-Jones ndi ochepa mokwanira kuti angathe kusefedwa ndi impso. Mapuloteniwo amathira mumkodzo.

Wopereka wanu atha kuyitanitsa mayeso awa:

• Kuzindikira zomwe zimayambitsa mapuloteni mkodzo
• Ngati muli ndi mapuloteni ambiri mumkodzo wanu
• Ngati muli ndi zizindikilo za khansa yamagazi yotchedwa multiple myeloma

Zotsatira zabwinobwino zikutanthauza kuti palibe mapuloteni a Bence-Jones omwe amapezeka mumkodzo wanu.

Mapuloteni a Bence-Jones sapezeka kawirikawiri mumkodzo. Ngati zilipo, nthawi zambiri zimalumikizidwa ndi ma myeloma angapo.

Zotsatira zosazolowereka zitha kukhalanso chifukwa cha:

• Mapuloteni omanga modabwitsa m'matumba ndi ziwalo (amyloidosis)
• Khansa yamagazi yotchedwa lymphocytic leukemia
• Khansa ya khansa (lymphoma)
• Kumanga m'magazi a protein yotchedwa M-protein (monoclonal gammopathy yofunika osadziwika; MGUS)
• Aakulu aimpso kulephera

Palibe zowopsa pamayesowa.

Maunyolo owala a immunoglobulin - mkodzo; Mkodzo mapuloteni a Bence-Jones

• Njira yamikodzo yamwamuna

Chernecky CC, Berger BJ. Mapuloteni electrophoresis - mkodzo. Mu: Chernecky CC, Berger BJ, olemba., Eds. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. St Louis, MO: Elsevier Saunders; 2013: 920-922.

(Adasankhidwa) Riley RS, McPherson RA. Kuwunika koyambirira kwa mkodzo. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 28.

Rajkumar SV, Dispenzieri A. Multiple myeloma ndi zovuta zina. Mu: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, olemba. Chipatala cha Abeloff's Oncology. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier; 2020: chap 101.