CSF oligoclonal banding

CSF oligoclonal banding ndiyeso yoyang'ana mapuloteni okhudzana ndi kutupa mu cerebrospinal fluid (CSF). CSF ndiye madzimadzi omveka bwino omwe amayenda m'malo ozungulira msana ndi ubongo.

Magulu a Oligoclonal ndi mapuloteni otchedwa ma immunoglobulins. Kukhalapo kwa mapuloteniwa kumawonetsa kutupa kwa mitsempha yayikulu. Kukhalapo kwa magulu a oligoclonal kungatanthauze kuti matenda a multiple sclerosis amapezeka.

Chitsanzo cha CSF chikufunika. Kubowola lumbar (mpopi wamtsempha) ndiyo njira yofala kwambiri yosonkhanitsira chitsanzochi.

Njira zina zosonkhanitsira CSF sizigwiritsidwa ntchito kawirikawiri, koma zitha kulimbikitsidwa nthawi zina. Zikuphatikizapo:

• Kutsekemera kwa zitsime
• Ventricular puncture
• Kuchotsa kwa CSF mu chubu chomwe chili kale mu CSF, monga kuda kapena kutulutsa kwamitsempha yamagetsi.

Chitsanzocho chitatengedwa, chimatumizidwa ku labu kukayezetsa.

Kuyesaku kumathandizira kuthandizira kupeza kwa multiple sclerosis (MS). Komabe, sizitsimikizira kuti ali ndi matendawa. Magulu a Oligoclonal mu CSF amathanso kuwonedwa m'matenda ena monga:

• Njira lupus erythematosus
• Matenda a kachirombo ka HIV
• Sitiroko

Nthawi zambiri, gulu limodzi kapena ayi liyenera kupezeka mu CSF.

Chidziwitso: Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pama laboratories osiyanasiyana. Lankhulani ndi wothandizira zaumoyo wanu za tanthauzo la zotsatira zanu zoyeserera.

Zitsanzo pamwambapa zikuwonetsa muyeso wamba wazotsatira zamayesowa. Ma labotale ena amagwiritsa ntchito miyeso yosiyana kapena amatha kuyesa mitundu yosiyanasiyana.

Pali zomangira ziwiri kapena zingapo zomwe zimapezeka mu CSF osati m'magazi. Izi zikhoza kukhala chizindikiro cha multiple sclerosis kapena kutupa kwina.

Cerebrospinal madzimadzi - immunofixation

• CSF oligoclonal banding - mndandanda
• Lumbar kuboola (tapampopi)

Deluca GC, Griggs RC. Njira kwa wodwala matenda amitsempha. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 368.

Karcher DS, McPherson RA. Cerebrospinal, synovial, madzi amtundu wa serous, ndi mitundu ina. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 29.