Mayeso a Glucose-6-phosphate dehydrogenase

Glucose-6-phosphate dehydrogenase (G6PD) ndi protein yomwe imathandizira maselo ofiira kugwira ntchito bwino. Kuyesa kwa G6PD kumayang'ana kuchuluka (ntchito) kwa chinthuchi m'maselo ofiira amwazi.

Muyenera kuyesa magazi.

Palibe kukonzekera kwapadera komwe kumafunikira.

Pamene singano imayikidwa kuti ikoke magazi, anthu ena amamva kupweteka pang'ono. Ena amangomva kubaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupunduka kapena kuvulala pang'ono. Izi posachedwa zichoka.

Wothandizira zaumoyo wanu angakulimbikitseni kuyesaku ngati muli ndi zofooka za G6PD. Izi zikutanthauza kuti mulibe zochitika zokwanira za G6PD.

Ntchito zochepa kwambiri za G6PD zimabweretsa kuwonongedwa kwa maselo ofiira amwazi. Njirayi imatchedwa hemolysis. Izi zikachitika, zimatchedwa gawo la hemolytic.

Magawo a Hemolytic amatha kuyambitsidwa ndi matenda, zakudya zina (monga nyemba za fava), ndi mankhwala ena, kuphatikiza:

• Mankhwala omwe amagwiritsidwa ntchito pochepetsa malungo
• Nitrofurantoin
• Phenacetin
• Chiyambi
• Sulfonamides
• Odzetsa okodzetsa
• Tolbutamide
• Quinidine

Makhalidwe abwinobwino amasiyanasiyana ndikudalira labotale yomwe agwiritsa ntchito. Ma lab ena amagwiritsa ntchito miyeso yosiyanasiyana kapena amayesa mitundu yosiyanasiyana. Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Zotsatira zachilendo zimatanthauza kuti muli ndi vuto la G6PD. Izi zitha kupangitsa kuchepa kwa magazi m'thupi mwazinthu zina.

Pali chiopsezo chochepa chotenga magazi anu. Mitsempha ndi mitsempha imasiyana mosiyanasiyana kuchokera pa munthu wina kupita kwina komanso kuchokera mbali imodzi ya thupi kupita mbali inayo. Kupeza magazi kuchokera kwa anthu ena kumatha kukhala kovuta kuposa ena.

Zowopsa zina zomwe zimakoka magazi ndi zochepa, koma mwina ndi izi:

• Kutaya magazi kwambiri
• Kukomoka kapena kumva mopepuka
• Ma punctures angapo kuti mupeze mitsempha
• Hematoma (magazi omanga pansi pa khungu)
• Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)

Mayeso a RBC G6PD; Chithunzi cha G6PD

Chernecky CC, Berger BJ. Glucose-6-phosphate dehydrogenase (G6PD, G-6-PD), yowonjezera - magazi. Mu: Chernecky CC, Berger BJ, olemba., Eds. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. St Louis, MO: Elsevier Saunders; 2013: 594-595.

Gallagher PG. Hemolytic anemias: maselo ofiira am'magazi komanso zopindika zamagetsi. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: mutu152.