Mayeso a mkodzo wa Cortisol

Kuyezetsa mkodzo wa cortisol kumayesa kuchuluka kwa cortisol mumkodzo. Cortisol ndi hormone ya glucocorticoid (steroid) yopangidwa ndi adrenal gland.

Cortisol amathanso kuyezedwa pogwiritsa ntchito kuyesa magazi kapena malovu.

Muyenera kuyesa mkodzo wa maola 24. Muyenera kusonkhanitsa mkodzo wanu kwa maola 24 muchidebe choperekedwa ndi labotale. Wothandizira zaumoyo wanu adzakuuzani momwe mungachitire izi. Tsatirani malangizo ndendende.

Chifukwa choti cortisol yopangidwa ndi adrenal gland imatha kusiyanasiyana, mayesowa angafunike kuchitika katatu kapena kupitilira apo kuti mumve bwino za kapangidwe kake ka cortisol.

Mutha kupemphedwa kuti musachite masewera olimbitsa thupi mwamphamvu tsiku lisanafike mayeso.

Muthanso kuuzidwa kuti musiye kumwa mankhwala omwe angakhudze mayeso, kuphatikiza:

• Mankhwala oletsa kulanda
• Estrogen
• Zopangidwa ndi anthu (zopanga) glucocorticoids, monga hydrocortisone, prednisone ndi prednisolone
• Androgens

Chiyesocho chimaphatikizapo kukodza kokha. Palibe kusapeza.

Kuyesaku kumachitika kuti muwone kuchuluka kwa cortisol yowonjezera kapena yotsika. Cortisol ndi hormone ya glucocorticoid (steroid) yotulutsidwa mu adrenal gland poyankha adrenocorticotropic hormone (ACTH). Imeneyi ndi timadzi timene timatulutsidwa mu ubongo wa pituitary. Cortisol imakhudza machitidwe amthupi osiyanasiyana. Imagwira nawo:

• Kukula kwa mafupa
• Kuthamanga kwa magazi
• Chitetezo cha mthupi
• Kagayidwe ka mafuta, chakudya, ndi mapuloteni
• Mchitidwe wamanjenje umagwira
• Kupsinjika

Matenda osiyanasiyana, monga Cushing syndrome ndi matenda a Addison, amatha kuyambitsa cortisol yochulukirapo kapena yochepa. Kuyeza msinkhu wa cortisol kumatha kuthandizira kuzindikira izi.

Mtundu wabwinobwino ndi 4 mpaka 40 mcg / maola 24 kapena 11 mpaka 110 nmol / tsiku.

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyana kapena amatha kuyesa mitundu yosiyanasiyana. Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Mulingo woposa wabwinobwino ungasonyeze:

• Cushing matenda, momwe chifuwa cha pituitary chimapanga ACTH yochulukirapo chifukwa chokula kwambiri kwa matenda am'mimbamo kapena chotupa m'matumbo
• Ectopic Cushing syndrome, momwe chotupa kunja kwa ma pituitary kapena adrenal glands chimapanga ACTH yochulukirapo
• Kukhumudwa kwakukulu
• Chotupa cha adrenal gland chomwe chimatulutsa cortisol wambiri
• Kupsinjika kwakukulu
• Matenda achilendo ambiri

Mlingo wotsika kuposa wamba ungasonyeze:

• Addison matenda omwe adrenal glands samatulutsa cortisol yokwanira
• Hypopituitarism momwe chiberekero cha pituitary sichimatanthauza kuti adrenal gland imatulutsa cortisol yokwanira
• Kuchepetsa kugwira ntchito kwa pituitary kapena adrenal ndi mankhwala a glucocorticoid kuphatikiza mapiritsi, mafuta apakhungu, eyedrops, inhalers, jakisoni wamagulu, chemotherapy

Palibe zowopsa pamayesowa.

24-hour free cortisol (UFC)

• Thirakiti lachikazi
• Njira yamkodzo wamwamuna

Chernecky CC, Berger BJ. Cortisol - mkodzo. Mu: Chernecky CC, Berger BJ, olemba., Eds. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. St Louis, MO: Elsevier Saunders; 2013: 389-390.

Stewart PM, Newell-Price JDC. Kachilombo kotchedwa adrenal cortex. Mu: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, olemba. Buku la Williams la Endocrinology. Wolemba 13. Philadelphia, PA: Elsevier; 2016: chap 15.